Synthesis, DNA cleavage and cytotoxicity of some novel cyclic peptide-2,6-dimethoxyhydroquinone-3-mercaptoacetic acid conjugates containing D-amino acids

Anti-Cancer Drug Design

Volumn 13, Issue 5, 1998, Pages 501-518

  Chen, Sen Liang ^a   Shun Wong, Ricky Ngok ^b   Lo, Vivian ^a   Chang, Suzi ^a   Chiang, Chi Der ^c   Sheh, Leung ^a  

^a TUNGHAI UNIVERSITY   (Taiwan)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

^c NONE

Author keywords

DNA cleavage studies; Enantiomeric and diastereomeric cyclic tripeptide cytotoxic agent conjugates; ESR studies; In vitro antitumor studies

Indexed keywords

ASCORBIC ACID; DNA; HYDROQUINONE DERIVATIVE; HYDROXYL RADICAL; PLASMID DNA; THIOGLYCOLIC ACID;

AGAR GEL ELECTROPHORESIS; ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DNA SUPERCOILING; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; LUNG CARCINOMA; METHODOLOGY; PRIORITY JOURNAL; STEREOISOMERISM;

AMINO ACIDS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; CHEMISTRY, PHYSICAL; DNA, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYDROQUINONES; MOLECULAR WEIGHT; PEPTIDES, CYCLIC; SPIN TRAPPING; STEREOISOMERISM; THIOGLYCOLATES; TUMOR CELLS, CULTURED;

EID: 7344266887     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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