Apparent interaction of dimethyl sulfoxide with cisplatin released from polymer delivery devices injected subcutaneously in dogs

Journal of Drug Targeting

Volumn 5, Issue 5, 1998, Pages 391-396

  Dernell, W S ^a   Straw, R C ^a,c   Withrow, S J ^a   Powers, B E ^a   Fujita, S M ^b   Yewey, G S ^b,d   Joseph, K F ^b   Dunn, R L ^b   Whitman, S L ^b   Southard, G L ^b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b QLT Inc   (United States)

^c West Chermiside Veterinary Clinic   (Australia)

^d Imutec Corporation   (Canada)

Author keywords

Canine; Cisplatin; Dimethyl sulfoxide; Osteosarcoma; Polymer

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DIMETHYL SULFOXIDE; POLYLACTIDE; POLYMER; SOLVENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DOG; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; TISSUE CULTURE;

EID: 7344257236     PISSN: 1061186X     EISSN: None     Source Type: Journal    
DOI: 10.3109/10611869808997866     Document Type: Article

References (8)

1. Dunn R.L., Yewey G.L., Fujita S.M., Josephs K.F., Whitman S.L., Southard G.L., Dernell W.S., Straw R.C., Withrow S.J. and Powers B.E. (1996) Sustained release of cisplatin in dogs from an injectable implant delivery system. J. Bioact. Comp. Polym., 11, 286-300.
2. Kerrison S., John S. and Sadler P.J. (1977) Solvolysis of cis-[Pt(NH3)2C12] in dimethyl sulfoxide and reactions of glycine with [PtCl3(Me2SO)] as probed by platinum-195 nuclear magnetic resonance shifts and platinum-195-nitrogen-15 coupling constants. J. Chem. Soc. Chem. Commun., 23, 861-863.
3. Jones M.M., Basinger M.A., Field L. and Holscher M.A. (1991) Coadministration of dimethyl sulfoxide reduces cisplatin nephrotoxicity. Anticancer Res., 11, 1939-1942.
4. Meek D.W., Straub D.K. and Drago R.S. (1960) Transition metal ion complexes of dimethyl sulfoxide. Molec. Biophys., 82, 6013-6016.
5. O'Brien M.G., Withrow S.J. and Straw R.C. (1993) Recent advances in the treatment of canine appendicular osteosarcoma. Comp. Cont. Ed. Pract. Vet., 15, 939-46.
6. Spodnick G.J., Berg J., Rand W.M., Schelling S.H., Couto G., Harvey H.J., Henderson R.A., MacEwen G., Mauldin N., McCaw D.L., Moore A.S., Morrison W., Norris A.M., O'Bradovich J., O'Keefe D.A., Page R., Ruslander D., Klausner J., Straw R., Thompson J.P. and Withrow S.J. (1992) Prognosis for dogs with appendicular osteosarcoma treated with amputation alone: 162 cases (1978-1988). J. Am. Vet. Med. Assoc., 200, 995-999.
7. Straw R.C., Withrow S.J., Douple E.B., Brekke J.H., Cooper M.H., Schwarz P.D., Greco D.S. and Powers B.E. (1994) The effects of cis-diamminedichloroplatinum II released from D,L-polylactic acid implanted adjacent to cortical allografts in dogs. J. Ortho. Res., 12, 871-877.
8. Withrow S.J., Straw R.C., Brekke J.H., Powers B.E., Cooper M.F., Ogilvie G.K., Lafferty M.H., Jameson V.J., O'Brien M.G., Douple E.B. and Dernell W.S. (1995) Slow release adjuvant cisplatin for treatment of metastatic canine osteosarcoma. Eur. J. Exp Musculoskel. Res., 4, 105-110.