Treatment of hemophagocytic lymphohistiocytosis, HLH, with bone marrow transplantation;Behandlung der hamophagozytischen lymphohistiozytose, HLH, mit knochenmarktransplantation

Klinische Padiatrie

Volumn 210, Issue 4, 1998, Pages 180-184

  Dürken, Matthias ^a   Schneider, Elisabeth M ^b   Blütters Sawatzki, Renate ^c   Stollmann Gibbels, Brigitte ^d   Neßler, Gernot ^e   Bretz, Robert ^f   Körholz, Dieter ^g   Probst, Eva Neumaier ^a   Holsten Griffin, Hilke ^a   Harps, Egmont ^a   Zander, Axel R ^a   Janka, Gritta E ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF ULM   (Germany)

^c UNIVERSITY HOSPITAL GIESSEN   (Germany)

^d Universitats Kinderklinik   (Switzerland)

^e Kinderklinik Karlsruhe ^*

^f Krankenanstalten Trier

^g UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

Bone marrow transplantation; Diagnostic criteria; Graft versus host disease; Hemophagocytic lymphohistiocytosis; Morbus farquhar; Unrelated donor

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; ETOPOSIDE; IMMUNOSUPPRESSIVE AGENT;

ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; BLINDNESS; CLINICAL ARTICLE; CYTOPENIA; FEVER; FOLLOW UP; GRAFT VERSUS HOST REACTION; HEMOPHAGOCYTIC SYNDROME; HEPATOSPLENOMEGALY; HISTIOCYTOSIS; HUMAN; HYPERTRIGLYCERIDEMIA; HYPOFIBRINOGENEMIA; IMMUNOSUPPRESSIVE TREATMENT; PHAGOCYTOSIS; QUADRIPLEGIA; SEIZURE; TREATMENT OUTCOME; BONE MARROW; BONE MARROW TRANSPLANTATION; CHILD; INFANT; PATHOLOGY; PRESCHOOL CHILD;

BONE MARROW; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; FOLLOW-UP STUDIES; GRAFT VS HOST DISEASE; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; INFANT; TREATMENT OUTCOME;

EID: 7344247125     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1043876     Document Type: Article

References (23)

1. Ambruso, D. R., T. Hays, W. J. Zwartjes, D. G. Tubergen, B. E. Favara: Successful treatment of lymphohistiocytic reticulosis with phagocytosis with epipodophyllotoxin VP 16-213. Cancer 45 (1980) 2516-2520
2. Aricò, M., G. Janka, A. Fischer, J.-I. Henter, S. Blanche, G. Elinder, M. Martinetti, M. P. Rusca for the FHL Study Group of the Histiocyte Society: Hemophagocytic lymphohistiocytosis. Report of 122 children from the international registry. Leukemia 10 (1996) 197-203
3. Baker, K. S., C. A. DeLaat, M. Steinbuch, T. G. Gross, R. S. Shapiro, B. Loechelt, R. Harris, A. H. Filipovich: Successful correction of hemophagocytic lymphohistiocytosis with related or unrelated bone marrow transplantation. Blood 89 (1997) 3857-3863
4. Bearman, S. I., F. R. Appelbaum, C. D. Buckner, F. Petersen, L. D. Fisher, R. A. Clift, E. D. Thomas: Regimen-related toxicity in patients undergoing bone marrow transplantation. J. Clin. Oncol. 6 (1988) 1562-1568
5. Beelen, D. W., E. Haralambie, H. Brandt, G. Linzenmeier, K. D. Müller, K. Quabeck, H. G. Sayer, U. Graeven, H. K. Mahmoud, U. W. Schaefer: Evidence that sustained growth suppression of intestinal anaerobic bacteria reduces the risk of acute graft-versus-host disease after sibling marrow transplantation. Blood 80 (1992) 2668-2676
6. Bolme, P., J.-J. Henter, J. Winiarski, G. Elinder, P. Ljungman, G. Lönnerholm, O. Ringdén: Allogeneic bone marrow transplantation for hemophagocytic lymphohistiocytosis in Sweden. Bone Marrow Transplant. 15 (1995) 331-335
7. Brown, R. E., W. P. Bowman, C. A. D'Cruz, T. E. Pick, J. E. Champion: Endoperoxidation, hyperprostaglandinemia, and hyperlipidemia in a case of erythrophagocytic lymphohistiocytosis. Reversal with VP-16 and indomethacin. Cancer 60 (1987) 2388-2393
8. Eife, R. G. E. Janka, B. H. Belohradsky, H. Holtmann: Natural killer cell function and interferon production in familial hemophagocytic lymphohistiocytosis. Pediatr. Hematol. Oncol. 6 (1989) 265-272
9. Farquhar, J. W., A. F. Claireaux: Familial hemophagocytic reticulosis. Arch. Dis. Child. 27 (1952) 519-525
10. Fischer, A., N. Cerf-Bensussun, S. Blanche, F. Le Deist, C. Bremard-Oury, G. Leverger, G. Schaison, A. Durandy, C. Griscelli: Allogeneic bone marrow transplantation for erythrophagocytic lymphohistiocytosis. J. Pediatr. 108 (1986) 267-270
11. Fischer, A., J. L. Virelizier, F. Arenzana-Seisdedos, N. Ferez, C. Nezelof, C. Griscelli: Treatment of four patients with erytrophagocytic lymphohistiocytosis by a combination of epipodophyllotoxin, steroids, intrathecal methotrexate, and cranial irradiation. Pediatrics 76 (1985) 263-268
12. Gencik, A., E. Signer, H. J. Müller: Genetic analysis of familial erythrophagocytic lymphohistiocytosis. Eur. J. Pediatrics 142 (1994) 248-252
13. Glucksberg, H., R. Storb, A. Fefer, C. Buckner, P. Neiman, R. Clift, K. Lerner, K. Thomas: Clinical manifestations of graft-versus-host disease in human recipients of marrow from HL-A-matched donors. Transplantation 18 (1974) 295-304
14. Haddad, E., M. L. Sulis, N. Jabado, S. Blanche, A. Fischer, M. Tardieu: Frequency and severity of central nervous system lesions in hemophagocytic lymphohistiocytosis. Blood 89 (1997) 794-800
15. Henter, J., G. Elinder, A. Ost, the FHL studv group of the Histiocyte Society: Diagnostic guidelines for hemphagocytic lymphohistiocytosis. Sem. Oncol. 18 (1991) 29-33
16. Henter, J.-I., G. Linder, O. Söder, M. Hansson, B. Andersson, U. Andersson: Hypercytokinema in familial hemophagocytic lymphohistiocytosis. Blood 78 (1991) 2918-2922
17. Jabado, N., E. R. de Graeff-Meeder, M. Cavazzana-Calvo, E. Haddad, F. Le Deist, M. Benkerrou, R. Dufourcq, S. Caillat, S. Blanche, A. Fischer: Treatment of familial hemophagocytic lymphohistiocytosis with bone marrow transplantation from HLA genetically nonidentical donors. Blood 90 (1997) 4743-4748
18. Janka, G. E: Familial hemophagocytic lymphohistiocytosis. Eur. J. Pediatr. 140 (1983) 221-230
19. McDonald, G. B., M. S. Hinds, L. D. Fisher, H. G. Schoch, J. L. Wolford, M. Banaji, B. J. Hardin, H. M. Shulman, R. A. Clift: Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: A cohort study of 355 patients. Ann. Intern. Med. 118 (1993) 255-267
20. Perez, N., J.-L. Virelizier, F. Arenzana-Seisdedos, A. Fischer, C. Griscelli: Impaired natural killer cell activity in lymphohistiocytosis syndrome. J. Pediatr. 104 (1984) 569-573
21. Poynton Ch., S. Jackson, C. Fegan, R. A. Barnes, J. A. Whittaker: Use of IgM enriched intravenous immunoglobulin (Pentaglohin) in bone marrow transplantation. Bone Marrow Transplant. 9 (1992) 451-457
22. Schneider, E. M., G. Pawelec, L. R. Shi, P. Wernet: A novel type of human T cell clones with highly potent natural killer-like cytotoxicity divorced from large granular lymphocyte morphology. J. Immunology 133 (1984) 173-179
23. Stéphan, J. L., J. Donadieu, F. Ledeist, S. Blanche, C. Griscelli, A. Fischer: Treatment of familial hemophagocytic lymphohistiocytosis with antithymocyte globulins, steroids, and cyclosporin A. Blood 82 (1993) 2319-2323