A randomized trial of solvent/detergent and standard fresh frozen plasma in the treatment of the coagulopathy seen during orthotopic liver transplantation

Vox Sanguinis

Volumn 74, Issue SUPPL. 1, 1998, Pages 225-229

  Freeman, Jonathan W ^a   Williamson, L M ^a,e   Llewelyn, C ^a   Fisher, N ^a   Allain, J P ^b   Bellamy, M ^d   Baglin, T P ^e   Klinc, J ^c   Ala, F A ^e   Smith, N ^e   Neuberger, J ^a   Wreghitt, T ^f  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d Leeds

^e NHS BLOOD AND TRANSPLANT   (United Kingdom)

^f Public Laboratory   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPLASMIN; BLOOD CLOTTING FACTOR 8; DETERGENT; FRESH FROZEN PLASMA; SOLVENT;

BLOOD CLOTTING; BLOOD CLOTTING DISORDER; BLOOD COMPONENT THERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FOLLOW UP; HUMAN; LIVER TRANSPLANTATION; MULTICENTER STUDY; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK; SEROCONVERSION; TIME; VIRUS INACTIVATION; VIRUS TRANSMISSION;

EID: 7344246551     PISSN: 00429007     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (11)

1. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ. The risk of transfusion-transmitted viral infections. N Engl J Med 1996;334:1685-90.
2. Horowitz B, Bonomo R, Prince AM, Chin SN, Brotman B, Schulman BW: Solvent/detergent- treated plasma: A virus-inactivated substitute for fresh frozen plasma. Blood 1992;79:826-31.
3. Pehta JC. Clinical studies with solvent/detergent- treated products. Trans Med Rev 1996;X:303-11.
4. Hellstern P, Sache H, Schwinn H, Oberfrank K. Manufacture and in vitro characterization of a solvent-detergent-treated human plasma. Vox Sang 1992;63:178-85.
5. Piquet Y, Janvier G, Selosse P, Doutremepvich C, Journeau J, Nicolle G, Platel D, Vezou G: Virus inactivation of fresh frozen plasma by a solvent detergent procedure: Biological results. Vox Sang 1992;63:251-56.
6. Harrison CN, Lawrie AS, Iqbal A, Hunter A, Machin SJ: Plasma exchange with solvent/detergent plasma of resistant thrombotic thrombocytopenic purpra. Brit J Haem 1996;94:756-58.
7. British Committee for Standards in Haematology, Working Party of the Blood Transfusion Task Force (Convenor: M Contreras). Guidelines for the use of fresh frozen plasma. Transfusion medicine 1992;2:57-63.
8. Guidelines for the Blood Transfusion Service. 2nd edition, HMSO, 1994.
9. Prowse C, Follett E, Prince A (eds). Hepatitis A virus Transmission by blood products. Vox Sang 1994:67 (suppl 1)
10. Prowse C, Ludlam CA, Yap PL. Human parvoviruse B19 and blood products. Vox Sang 1997;72:1-10
11. Solheim BG, Svennevig JL, Rollag H. Viral safety of solvent/detergent treated plasma (Octaplas). Infusionstherapie und transfusionsmedizin 1997;24:209 (A339)