Structural analysis of the CD5 antigen expression, disulphide bond analysis and physical characterisation of CD5 scavenger receptor superfamily domain 1

European Journal of Biochemistry

Volumn 257, Issue 1, 1998, Pages 131-141

  Mcalister, Mark S B ^a   Brown, Marion H ^b   Willis, Antony C ^c   Rudd, Pauline M ^c   Harvey, David J ^c   Aplin, Robin ^d   Shotton, David M ^e   Dwek, Raymond A ^c   Barclay, A Neil ^b   Driscoll, Paul C ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

CD5; Disulphide bonds; Glycosylation; NMR spectroscopy; Scavenger receptor cysteine rich

Indexed keywords

CD5 ANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; CHO CELL; DISULFIDE BOND; ELECTRON MICROSCOPY; MOLECULAR INTERACTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RECEPTOR AFFINITY; STRUCTURE ANALYSIS; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD5; CARBOHYDRATES; CHO CELLS; CIRCULAR DICHROISM; CRICETINAE; DISULFIDES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON; PICHIA; RATS; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS B;

ANIMALIA; CHIMAERA; CRICETINAE; CRICETULUS GRISEUS; PICHIA PASTORIS;

EID: 7344220970     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2570131.x     Document Type: Article

References (57)

1. Barclay, A. N., Brown, M. H., Law, S. K. A., McKnight, A. J., Tomlinson, M. G. & van der Merwe, P. A. (1997) The Leukocyte antigen factsbook, 2nd edn, Academic Press, London.
2. Tarakhovsky, A., Kanner, S. B., Hombach, J., Ledbetter, J. A., Muller, W., Killeen, N. & Rajewsky, K. (1995) A role for CD5 in TCR-mediated signal-transduction and thymocyte selection, Science 269, 535-537.
3. Bikah, G., Carey, J., Ciallella, J. R., Tarakhovsky, A. & Bondada, S. (1996) CD5-mediated negative regulation of antigen receptor-mediated growth signals in B-1 B-cells, Science 274, 1906-1909.
4. Freeman, M., Ashkenas, J., Rees, D. J. G., Kingsley, D. M., Copeland, N. G., Jenkins, N. A. & Krieger, M. (1990) An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type-I and type-II murine macrophage scavenger receptors, Proc. Natl Acad. Sci. USA 87, 8810-8814.
5. Aruffo, A., Melnick, M. B., Linsley, P. S. & Seed, B. (1991) The lymphocyte glycoprotein CD6 contains a repeated domain structure characteristic of a new family of cell surface and secreted proteins, J. Exp. Med. 174, 949-952.
6. Aruffo, A., Bowen, M. A., Patel, D. D., Haynes, B. F., Starling, G. C., Gebe, J. A. & Bajorath, J. (1997) CD6-ligand interactions: a paradigm for SRCR domain function? Immunol. Today 18, 498-504.
7. Gebe, J. A., Keiner, P. A., Ring, H. Z., Li, X., Francke, U. & Aruffo, A. (1997) Molecular cloning, mapping to human chromosome 1 q21-q23, and cell binding characteristics of SP-alpha, a new member of the scavenger receptor cysteine-rich (SRCR) family of proteins. J. Biol. Chem. 272, 6151-6158.
8. Krieger, M. & Herz, J. (1994) Structures of multiligand lipoprotein receptors - macrophage scavenger receptors and LDL receptor-related protein (LPR), Annu. Rev. Biochem. 63, 601-637.
9. Elomaa, O., Kangas, M., Sahlberg, C., Tuukkanen, J., Sormunen, R., Liakka, A., Thesleff, I., Kraal, G. & Tryggvason, K. (1995) Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed on a subset of macrophages, Cell 80, 603-609.
10. Law, S. K. A., Micklem, K. J., Shaw, J. M., Zhang, X.-P., Dong, Y., Willis, A. C. & Mason, D. Y. (1993) A new macrophage differentiation antigen which is a new member of the scavenger receptor superfamily, Eur. J. Immunol. 23, 2320-2325.
11. Wijngaard, P. L. J., Metzelaar, M. J., MacHugh, N. D., Morrison, W. I. & Clevers, H. C. (1992) Molecular characterisation of the WC1 antigen expressed specifically on bovine CD4-CD8-γδ T lymphocytes, J. Immunol. 149, 3273-3277.
12. Resnick, D., Pearson, A. & Krieger, M. (1994) The SRCR superfamily: a family reminiscent of the Ig superfamily, Trends Biochem. Sci. 19, 5-8.
13. Bowen, M. A., Patel, D. D., Li, X., Modrell, B., Malacko, A. R., Wang, W. C., Marquardt, H., Neubauer, M., Pesando, J. M., Franke, U., Haynes, B. F. & Aruffo, A. (1995) Identification and characterisation of a 100-kD ligand for CD6 on human thymic epithelial cells, J. Exp. Med. 181, 2213-2220.
14. Whitney, G. S., Starling, G. C., Bowen, M. A., Modrell, B., Siadak, A. W. & Aruffo, A. (1995) The membrane-proximal scavenger receptor cysteine-rich domain of CD6 contains the activated leukocyte cell adhesion molecule binding site, J. Biol. Chem. 270, 18 187-18 190.
15. Bodian, D. L., Skonier, J. E., Bowen, M. A., Neubauer, M., Sidak, A. W., Aruffo, A. & Bajorath, J. (1997) Identification of residues in CD6 which are critical for ligand binding, Biochemistry 36, 2637-2641.
16. Beyers, A. D., Spruyt, L. L. & Williams, A. J. (1992) Molecular associations between the T-lymphocyte antigen receptor complex and the surface antigens CD2, CD4, or CD8 and CD5, Proc. Natl Acad. Sci. USA 89, 2945-2949.
17. Brown, M. H. & Barclay, A. N. (1994) Expression of immunoglobulin and scavenger receptor superfamily domains as chimaeric proteins with domains 3 and 4 of CD4 for ligand analysis, Protein Eng. 7, 515-521.
18. Jones, N. H., Clabby, M. L., Dialynas, D. P., Huang, H.-J. S., Herzenberg, L. A. & Strominger, J. L. (1986) Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu1, Nature 323, 346-349.
19. Cockett, M. I., Bebbington, C. R. & Yaranton, G. T. (1990) High-level expression of tissue inhibitors of metalloproteinases in Chinese hamster ovary cells using glutamine synthetatase gene amplification, Bio-technology (NY) 8, 662-667.
20. Vermeer, L. A., Deboer, N. K., Bucci, C., Bos, N. A., Kroese, F. G. M. & Alberti, S. (1994) MRC OX19 recognises the rat CD5 surface glycoprotein, but does not provide evidence for a population of CD5(bright) B-cells, Eur. J. Immunol. 24, 585-592.
21. Davis, S. J., Ward, H. A., Puklavec, M. J., Willis, A. C., Williams, A. F. & Barclay, A. N. (1990) High level expression in Chinese hamster ovary cells of soluble forms of CD4 lymphocyte glycoprotein including glycosylation variants, J. Biol. Chem. 265, 10 410-10 418.
22. Scorer, C. A., Clare, J. J., McCombie, W. R., Romanos, M. A. & Sreekrishna, K. (1994) Rapid selection using G418 of high copy number transformants of Pichia pastoris for high-level foreign gene-expression, Bio-technology (NY) 12, 181-184.
23. Hennessey, J. P. & Johnson, W. C. (1981) Subunit interactions of transcarboxylase as studied by circular-dichroism, Biochemistry 20, 1085-1094.
24. Driscoll, P. C., Clore, G. M., Beress, L. & Gronenborn, A. M. (1989) A proton nuclear magnetic-resonance study of the antihypertensive and antiviral protein BDS-1 from sea-anemone Anemonia sulcata - sequential and stereospecific resonance assignment and secondary structure, Biochemistry 28, 2178-2187.
25. Waltho, J. P. & Cavanagh, J. (1993) Practical aspects of recording multidimensional NMR-spectra in water with flat base-lines, J. Magn. Reson. 103, 338-348.
26. Brown, S. C., Weber, P. L. & Mueller, L. (1988) Towards complete assignment of H-1-NMR spectra in proteins, J. Magn. Reson. 77, 166-169.
27. Marion, D., Ikura, M. & Bax, A. (1989) Improved solvent suppression in one-dimensional and two-dimensional NMR-spectra by deconvolution of time-domain data, J. Magn. Reson. 84, 425-430.
28. Shotton, D. M., Burke, B. E. & Branton, D. (1979) The molecular structure of human erythrocyte spectrin. Biophysical and electron microscopic studies, J. Mol. Biol. 131, 303-329.
29. Woollett, G. R., Williams, A. F. & Shotton, D. M. (1985) Visualization by low-angle shadowing of the leukocyte-common antigen - a major cell-surface glycoprotein of lymphocytes, EMBO J. 4, 2827-2830.
30. Ashford, D., Dwek, R. A., Welply, J. K., Amataykul, S., Homans, S. W., Lis, H., Taylor, G. N., Sharon, N. & Rademacher, T. W. (1987) The β1-2-D-xylose and α1-3-D-fucose substituted N-linked oligosaccharides from Erythrina crystagalli lectin. Isolation, characterization and comparison with other legume lectins, Eur. J. Biochem 166, 311-320.
31. Guile, G. R., Wong, S. Y. C. & Dwek, R. A. (1994) Analytical and preparative separation of anionic oligosaccharides by weak anion exchange high performance liquid chromatography on an inert polymer column, Anal. Biochem. 222, 231-235.
32. Bordoli, R. S., Howes, K., Vickers, R. G., Bateman, R. H. & Harvey, D. J. (1994) Matrix-assisted laser-desorption mass-spectroscopy on a magnetic-sector instrument fitted with an array detector, Rapid Commun. Mass Spectrom. 8, 585-589.
33. Guisez, Y., Tison, B., Vandekerckhove, J., Demolder, J., Bauw, G., Haegeman, G., Fiers, W. & Contreras, R. (1991) Production and purification of recombinant human interleukin-6 secreted by the yeast S. cerevisiae, Eur. J. Biochem. 198, 217-222.
34. Grinna, L. S. & Tschopp, J. F. (1989) Size distribution and general functional features of N-linked oligosaccharides from the methylotrophic yeast, Pichia pastoris, Yeast 5, 107-115.
35. Thim, L., Hansen, M. T., Norris, K., Hoegh, I., Boel, E., Forstrom, J., Ammerer, G. & Fiil, N. (1986) Secretion and processing of insulin precursors in yeast, Proc. Natl Acad. Sci. USA 83, 6766-6770.
36. McAlister, M. S. B., Davis, B., Pfuhl, M. & Driscoll, P. C. (1998) Towards the structure of an SRCR domain from human CD5: Engineering a glycoprotein for superior characteristics in NMR experiments, Protein Eng., in the press.
37. Guile, G. G., Rudd, P. M., Wing, D. R., Prime, S. B. & Dwek, R. A. (1996) Method for separating oligosaccharide mixtures and analysing sugarprints, Anal. Biochem. 240, 210-226.
38. Edge, C. J., Rademacher, T. W., Wormald, M., Parekh, R. B., Butters, T. D., Wing, D. R. & Dwek, R. A. (1992) Fast sequencing of oligosaccharides: the reagent array analysis method, Proc. Natl Acad. Sci. USA 89, 6338-6342.
39. Cregg, J. M., Vedick, T. S. & Raschke, W. C. (1993) Recent advances in expression of foreign genes in Pichia pastoris, Biotechnology (NY) 11, 905-910
40. Romanos, M. A. (1995) Advances in the use of Pichia pastoris for high-level gene expression, Curr. Opin. Biotechnol. 6, 527-533.
41. White, C. E., Hunter, M. J., Meininger, D. P., White, L. R. & Komives, E. A. (1995) Large-scale expression, purification and characterisation of small fragments of thrombomodulin: the roles of the sixth domain and of methioine 388, Protein Eng. 8, 1177-1187.
42. Fiedler, K. & Simons, K. (1995) The role of N-glycans in the secretory pathway, Cell 81, 309-312.
43. Gahmberg, C. G. & Tolvanen, M. (1996) Why mammalian cell-surface proteins are glycoproteins, Trends Biochem. Sci. 21, 308-311.
44. Bisello, A., Greenberg, Z., Behar, V., Rosenblatt, M., Suva, L. J. C. & Horev, M. (1996) Role of glycosylation in expression and function of the human parathyroid hormone-related protein receptor, Biochemistry 35, 15 890-15 895.
45. Holmgren, A. & Branden, C.-I. (1989) Crystal-structure of chaperone protein papD reveals an immunolglobulin fold, Nature 342, 248-251.
46. Williams, A. F. (1987) A year in the life of the immunoglobulin superfamily, Immunol. Today 8, 298-303.
47. Jones, D. T., Taylor, W. R. & Thornton, J. M. (1992) A new approach to protein fold recognition, Nature 358, 86-89.
48. Resnick, D., Chatterton, J. E., Schwartz, K., Slayter, H. & Krieger, M. (1996) Structures of class A macrophage scavenger receptors, J. Biol. Chem. 271, 26 924-26 930.
49. Elomaa, O., Sankala, M., Pikkarainen, T., Bergmann, U., Tuuttila, A., Raatikainen-Ahkas, A., Sariola, H. & Tryggvason, K. (1998) Structure of the Human Macrophage MARCO Receptor and Characterisation of its Bacteria-binding Region, J. Biol. Chem. 273, 4530-4538.
50. Laroche, Y., Storme, V., de Meutter, J., Messens, J. & Lauwereys, M. (1994) High-level secretion and very efficient isotopic labelling of tick anticoagulant peptide (TAP) expressed in the methylotrophic yeast, Pichia pastoris, Bio-technology (NY) 12, 1119-1124.
51. Brady, R. L., Dodson, E. J., Dodson, G. G., Lange, G., Davis, S. J., Williams, A. F. & Barclay, A. N. (1993) Crystal structure of domain-3 and domain-4 of rat CD4: relation to the N-terminal domains, Science 260, 979-983.
52. Chang, C. Y. Y., Sastry, K. N., Gillies, S. D., Ezekowitz, R. A. B. & Sheriff, S. (1994) Crystallization and preliminary X-ray analysis of a trimeric form of human mannose binding protein, J. Mol. Biol. 241, 125-127.
53. Johnston, G. I., Kurosky, A. & McEver, R. P. (1989) Structural and biosynthetic-studies of the granule membrane-protein GMP-140, from humun-platlets and endothelial cells, J. Mol. Chem. 264, 1816-1823.
54. Cyster, J. C., Shotton, D. M. & Williams, A. F. (1991) The dimensions of the T-lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation, EMBO J. 10, 893-902.
55. Leahy, D. J., Axel, R. & Hendrickson, W. A. (1992) Crystal structure of a soluble form of the human T-cell coreceptor CD8 at 2.6 A resolution, Cell 68, 1145-1162.
56. Kuwano, M., Seguchi, T. & Ono, M. (1991) Glycosylation mutations of serine/threonine-linked oligosaccharides in low-density-lipoprotein receptor - indispensible roles of O-glycosylation, J. Cell Science 98, 131-134.
57. Rudd, P. M., Wormald, M. R., Harvey, D. J., Devashayem, M., McAlister, M. S. B., Brown, M. H., Davis, S. J., Barclay, A. N. & Dwek, R. A. (1998) Oligosaccharide processing in the Lyr6, scavenger receptor and immunoglobulin superfamilies - implications for roles for glycosylation on cell surface molecules, Glycobiology, in the press.