Quantitative study on polymorphic form in solution crystallization of clopidogrel hydrogen sulfate

Industrial and Engineering Chemistry Research

Volumn 48, Issue 24, 2009, Pages 11133-11139

  Kim, Hye Jin ^a   Kim, Kwang Joo ^a  

^a Hanbat National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; CONCENTRATION OF; HYDROGEN SULFATE; LIQUID CONCENTRATION; MEASURING TECHNIQUE; MULTIVARIATE DATA ANALYSIS; POLYMORPH TRANSFORMATION; POLYMORPHIC COMPOSITION; POLYMORPHIC FORMS; PROCESS CONDITION; QUANTITATIVE STUDY; SOLUTE CONCENTRATIONS; SOLUTION CRYSTALLIZATION; TRANSFORMATION PROCESS;

CONCENTRATION (PROCESS); CRYSTALLIZATION; MULTIVARIANT ANALYSIS; POLYMORPHISM; ULTRASONIC MEASUREMENT; ULTRASONICS;

ULTRASONIC TESTING;

EID: 73349141979     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie900715w     Document Type: Article

References (22)

1. Haleblian, J.; McCrone, W. Pharmaceutical applications of polymorphism. J. Pharm. Sci. 1969, 58, 911-929.
2. Laird, T. Special feature section: Polymorphism and crystallization. Org. Process Res. Dev. 2000, 4, 370-371.
3. Otsuka, M.; Ofusa, T.; Matsuda, Y. Effect of environmental humidity on the transformation pathway of carbamazepine polymorphic modifications during grinding. Colloids Surf., B 1999, 13, 263-273.
4. Zhang, G. Z.; Gu, C.; Zell, M. T.; Burkhardt, R. T.; Munson, E. J.; Grant, D. W. Crystallization and transitions of sulfamerazine polymorphs. J. Pharm. Sci. 2002, 91, 1089-1100.
5. Ostwald, W. Studien ueber die Bildung und Umwandlung fester Koerper. Z. Phys. Chem. 1897, 22, 289-330.
6. Tishmack, P. A. Solid-state nuclear magnetic resonance spectroscopy -pharmaceutical applications. J. Pharm. Sci. 2003, 92, 441-474.
7. Robert, T. B.; Sperger, D. M.; Isbester, P. K.; Munson, E. J. Solidstate NMR spectroscopy in pharmaceutical research and analysis. Trends Anal. Chem. 2006, 25, 977-984.
8. Ikeda, Y.; Hirayama, T.; Terada, K. Application of thermally stimulated current measurement to the polymorphic characterization of drug substances. Thermochim. Acta 2005, 31, 195-199.
9. Gamberini, M. C.; Baraldi, C.; Tinti, A.; Rustichelli, C.; Ferioli, V.; Gamberini, G. Solid state characterization of chloramphenicol palmitate: Raman spectroscopy applied to pharmaceutical polymorphs. J. Mol. Struct. 2006, 785, 216-224.
10. Blanco, M.; Villar, A. Development and validation of a method form the polymorphic analysis of pharmaceutical preparations using near infrared spectroscopy. J. Pharm. Sci. 2003, 92, 823-830.
11. Kim, H. J.; Kim, K. J. In-situ monitoring of polymorph transformation of clopidogrel hydrogen sulfate using measurement of ultrasonic velocity. J. Pharm. Sci. 2008, 97, 4473-4484.
12. Sayan, P.; Ulrich, J. The effect of particle size and suspension density on the measurement of ultrasonic velocity in aqueous solutions. Chem. Eng. Process. 2002, 41, 281-287.
13. Omar, W.; Ulrich, J. Application of ultrasonics in the on-line determination of supersaturation. Cryst. Res. Technol. 1999, 34, 379-389.
14. Titiz-Sargut, S.; Ulrich, J. Application of protected ultrasound sensor for determination of the width of the metastable zone width. Chem. Eng. Process. 2003, 42, 841-846.
15. Veverka, M.; Vodny, S.; Veverkova, E.; Hajicek, J.; Stepankova, H. Method for manufacturing crystalline form I of clopidogrel hydrogen sulphate. U.S. Patent 525,341, 2006.
16. Bousquet, A.; Castro, B.; Saint-Germain, J. Polymorphic form of clopidogrel hydrogen sulphate. U.S. Patent 64,291,910, 2002.
17. Kim, H. J.; Kim, K. J. Crystallization of Clopidogrel in Solvent, Report of Hanbat National University Korea, 2007.
18. McClements, D. J. Ultrasonic characterization of emulsions and suspensions. Adv. Colloid Interface Sci. 1991, 37, 33-72.
19. McClements, D. J. Ultrasonic NDT of foods and drinks. In International Advances in Nondestructive Testing; McGonnagle, W. J., Ed.; Gordon & Breach Science: Switzerland, 1994; Vol. 17, pp 63-95.
20. McClements, D. J.; Povey, M. J. W. Ultrasonic analysis of edible fats and oils. Ultrasonics 1992, 30, 383-388.
21. Wang, F.; Wachter, J. A.; Antosz, F. J.; Berglund, K. A. An investigation of solvent-mediated polymorphic transformation of progesterone using in situ Raman spectroscopy. Org. Process Res. Dev. 2000, 44, 391-395.
22. Starbuck, C.; Spartalis, W.; Wang, J.; Fernandez, P.; Lindemann, C. M.; Zhou, G. X.; Ge, Z. Process optimization of a complex pharmaceutical polymorphic system via in situ Raman spectroscopy. Cryst. Growth Des. 2002, 2, 515-522.