Multivariate statistical mapping of spectroscopic imaging data

Magnetic Resonance in Medicine

Volumn 63, Issue 1, 2010, Pages 20-24

  Young, Karl ^a,c   Govind, Varan ^b   Sharma, Khema ^b   Studholme, Colin ^a,c   Maudsley, Andrew A ^b   Schuff, Norbert ^a,c  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amytrophic lateral sclerosis; Brain metabolism; Multivariate analysis; Simulation; Spectroscopic imaging

Indexed keywords

BIOMOLECULES; MAGNETIC RESONANCE; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETISM; MAPPING; METABOLISM; METABOLITES; MULTIVARIANT ANALYSIS; NEURONS; SPECTROSCOPIC ANALYSIS;

AMYTROPHIC LATERAL SCLEROSIS; BRAIN METABOLISM; MULTI VARIATE ANALYSIS; SIMULATION; SPECTROSCOPIC IMAGING;

BRAIN MAPPING;

CHOLINE; N ACETYLASPARTIC ACID;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN DISEASE; BRAIN MAPPING; BRAIN METABOLISM; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; MALE; METABOLIC DISORDER; METABOLITE; MOTONEURON; MULTIVARIATE ANALYSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; SIMULATION; UNIVARIATE ANALYSIS; VALIDATION STUDY;

EID: 73349140794     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.22190     Document Type: Article

References (25)

1. Maudsley AA, Darkazanli A, Alger JR, Hall LO, Schuff N, Studholme C, Yu Y, Ebel A, Frew A, Goldgof D, Gu Y, Pagare R, Rousseau F, Sivasankaran K, Soher BJ, Weber P, Young K, Zhu X. Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. NMR Biomed 2006;19:492-503.
2. Thompson PM, Miller MI, Poldrack RA, Nichols TE, Taylor JE, Worsley KJ, Ratnanather JT. Special issue on mathematics in brain imaging. NeuroImage 2009;45:S1-S2.
3. Worsley KJ, Taylor JE, Tomaiuolo F, Lerch J. Unified univariate and multivariate random field theory. NeuroImage 2004;23(suppl 1): S189-S195.
4. Thompson PM, Toga AW. Detection, visualization and animation of abnormal anatomic structure with a deformable probabilistic brain atlas based on random vector field transformations. Med Image Anal 1997;1997:271-294.
5. Avants B, Duda JT, Kim J, Zhang H, Pluta J, Gee JC, Whyte J. Multivariate analysis of structural and diffusion imaging in traumatic brain injury. Acad Radiol 2008;15:1360-1375.
6. Luts J, Laudadio T, Idema AJ, Simonetti AW, Heerschap A, Vandermeulen, Suykens JA, Van Huffel S. Nosologic imaging of the brain: segmentation and classification using MRI and MRSI. NMR Biomed 2009;22:374-390.
7. Marjanska M, Curran GL, Wengenack TM, Henry PG, Bliss RL, Poduslo JF, Jack CR Jr, Ugurbil K, Garwood M. Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy. Proc Natl Acad Sci U|S|A 2005;102:11906-11910.
8. 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment. BMC Neurosci 2009;10:33.
9. Devos A, Simonetti AW, van der Graaf M, Lukas L, Suykens JA, Vanhamme L, Buydens LM, Heerschap A, Van Huffel S. The use of multivariate MR imaging intensities versus metabolic data from MR spectroscopic imaging for brain tumour classification. J Magn Reson 2005;173:218-228.
10. Masters CL, Cappai R, Barnham KJ, Villemagne VL. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J Neurochem 2006;97:1700-1725.
11. Neusch C, Bähr M, Schneider-Gold C. Glia cells in amyotrophic lateral sclerosis: new clues to understanding an old disease? Muscle Nerve 2007;35:712-724.
12. Kaiser LG, Young K, Meyerhoff J, Mueller SG, Matson GB. A detailed analysis of localized J-difference GABA editing: theoretical and experimental study at 4 T. NMR Biomed 2008;21:22-32.
13. Terpstra M, Marjanska M, Henry PG, Tkác I, Gruetter R. Detection of an antioxidant profile in the human brain in vivo via double editing with MEGA-PRESS. Magn Reson Med 2006;56:1192-1199.
14. Haupt CI, Kiefer AP, Maudsley AA. In-plane motion correction for MR spectroscopic imaging. Magn Reson Med 1998;39:749-753.
15. Collins DL, Zijdenbos AP, Kollokian V, Sled JG, Kabani NJ, Holmes CJ, Evans A. Design and construction of a realistic digital brain phantom. IEEE Trans Med Imaging 1998;17:463-468.
16. Ihaka R, Gentleman R. R: a language for data analysis and graphics. J Comput Graphical Stat 1996;5:299-314.
17. Marchini JL, Lafaye de Micheaux P. AnalyzeFMRI: functions for analysis of fMRI datasets stored in the ANALYZE or NIFTI format. R package version. 2008;1.1-1.10.
18. Strimmer K. fdrtool: a versatile R package for estimating local and tail area-based false discovery rates. Bioinformatics 2008;24:1461-1462.
19. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc 1995;57:289-300.
20. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using false discovery rate. Neuroimage 2002;15:870-878.
21. Maudsley AA, Domenig C, Govind V, Darkazanli A, Studholme C, Arheart K, Bloomer C. Mapping of brain metabolite distributions by volumetric proton MR spectroscopic imaging (MRSI). Magn Reson Med 2009;61:548-559.
22. Chard DT, McLean MA, Parker GJ, MacManus DG, Miller DH. Reproducibility of in vivo metabolite quantification with proton magnetic resonance spectroscopic imaging. J Magn Reson Imaging 2002;15: 219-225.
23. Schuff N, Rooney WD, Miller R, Gelinas DF, Amend DL, Maudsley AA, Weiner MW. Reanalysis of multislice (1)H MRSI in amyotrophic lateral sclerosis. Magn Reson Imaging 2001;45:513-516.
24. Block W, Karitzky J, Träber F, Pohl C, Keller E, Mundegar RR, Lamerichs R, Rink H, Ries F, Schild HH, Jerusalem F. Proton magnetic resonance spectroscopy of the primary motor cortex in patients with motor neuron disease: subgroup analysis and follow-up measurements. Arch Neurol 1998;55:931-936.
25. Sarac H, Zagar M, Vranjes D, Henigsberg N, Bilić E, Pavlisa G. Magnetic resonance imaging and magnetic resonance spectroscopy in a patient with amyotrophic lateral sclerosis and frontotemporal dementia. Coll Antropol 2008;32(suppl 1):205-210.