A curve-fitting approach to estimate the arterial plasma input function for the assessment of glucose metabolic rate and response to treatment

Journal of Nuclear Medicine

Volumn 50, Issue 12, 2009, Pages 1933-1939

  Vriens, Dennis ^a   De Geus Oei, Lioe Fee ^a   Oyen, Wim J G ^a   Visser, Eric P ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

18F FDG; Body fluid compartments; Chemotherapy; Input function; Least squares analysis; Pharmacokinetics; Positron emission tomography; Theoretical models; Therapy monitoring; Tissue distribution

Indexed keywords

ANTINEOPLASTIC AGENT; FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT;

ADULT; AGED; AREA UNDER THE CURVE; ARTERIAL PLASMA TIME ACTIVITY CONCENTRATION CURVE; ARTICLE; BLOOD SAMPLING; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SCINTISCANNING; COLORECTAL CANCER; CONTROLLED STUDY; CURVE FITTING; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG MONITORING; FEMALE; GLUCOSE METABOLISM; GOLD STANDARD; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; MULTIPLE CYCLE TREATMENT; PARAMETER; PLASMA CONCENTRATION-TIME CURVE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TREATMENT RESPONSE; ARTERY; BIOLOGICAL MODEL; BLOOD; GLUCOSE BLOOD LEVEL; METABOLISM; METHODOLOGY; MIDDLE AGED; NEOPLASM; REFERENCE VALUE; REPRODUCIBILITY; SCINTISCANNING; STANDARD; TREATMENT OUTCOME;

ADULT; AGED; ARTERIES; BLOOD GLUCOSE; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; TREATMENT OUTCOME;

EID: 73349137626     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.065243     Document Type: Article

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