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Volumn 15, Issue 10, 2009, Pages 3049-3059

Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGES; DOSIMETRY; FLOWCHARTING; FLUORESCENCE; GENE THERAPY; GENE TRANSFER; PROTEINS; STEM CELLS;

EID: 73349130817     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2009.0045     Document Type: Article
Times cited : (44)

References (39)
  • 1
    • 65349131822 scopus 로고    scopus 로고
    • Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation
    • Rooney, G.E., Howard, L., O'Brien, T., Windebank, A.J., and Barry, F.P. Elevation of cAMP in mesenchymal stem cells transiently upregulates neural markers rather than inducing neural differentiation. Stem Cells Dev 18, 387, 2008.
    • (2008) Stem Cells Dev , vol.18 , pp. 387
    • Rooney, G.E.1    Howard, L.2    O'Brien, T.3    Windebank, A.J.4    Barry, F.P.5
  • 2
    • 0037775809 scopus 로고    scopus 로고
    • Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity
    • Vallieres, L., and Sawchenko, P.E. Bone marrow-derived cells that populate the adult mouse brain preserve their hematopoietic identity. J Neurosci 23, 5197, 2003.
    • (2003) J Neurosci , vol.23 , pp. 5197
    • Vallieres, L.1    Sawchenko, P.E.2
  • 3
    • 2442666643 scopus 로고    scopus 로고
    • Adult bone marrow stromal cells in the em-bryonic brain: Engraftment, migration, differentiation, and long-term survival
    • Munoz-Elias, G., Marcus, A.J., Coyne, T.M., Woodbury, D., and Black, I.B. Adult bone marrow stromal cells in the em-bryonic brain: engraftment, migration, differentiation, and long-term survival. J Neurosci 24, 4585, 2004.
    • (2004) J Neurosci , vol.24 , pp. 4585
    • Munoz-Elias, G.1    Marcus, A.J.2    Coyne, T.M.3    Woodbury, D.4    Black, I.B.5
  • 4
    • 3042801100 scopus 로고    scopus 로고
    • Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype
    • Neuhuber, B., Gallo, G., Howard, L., Kostura, L., Mackay, A., and Fischer, I. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J Neurosci Res 77, 192, 2004.
    • (2004) J Neurosci Res , vol.77 , pp. 192
    • Neuhuber, B.1    Gallo, G.2    Howard, L.3    Kostura, L.4    MacKay, A.5    Fischer, I.6
  • 5
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differenti-ate into neurons
    • Woodbury, D., Schwarz, E.J., Prockop, D.J., and Black, I.B. Adult rat and human bone marrow stromal cells differenti-ate into neurons. J Neurosci Res 61, 364, 2000.
    • (2000) J Neurosci Res , vol.61 , pp. 364
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3    Black, I.B.4
  • 7
    • 33746862992 scopus 로고    scopus 로고
    • Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice
    • Zhang, J., Li, Y., Lu, M., Cui, Y., Chen, J., Noffsinger, L., Elias, S.B., and Chopp, M. Bone marrow stromal cells reduce axonal loss in experimental autoimmune encephalomyelitis mice. J Neurosci Res 84, 587, 2006.
    • (2006) J Neurosci Res , vol.84 , pp. 587
    • Zhang, J.1    Li, Y.2    Lu, M.3    Cui, Y.4    Chen, J.5    Noffsinger, L.6    Elias, S.B.7    Chopp, M.8
  • 8
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells ex-hibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao, L.R., Duan, W.M., Reyes, M., Keene, C.D., Verfaillie, C.M., and Low, W.C. Human bone marrow stem cells ex-hibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol174, 11, 2002.
    • (2002) Exp Neurol , vol.174 , pp. 11
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3    Keene, C.D.4    Verfaillie, C.M.5    Low, W.C.6
  • 10
    • 0037406029 scopus 로고    scopus 로고
    • Bone marrow stromal cells enhance differentiation of cocultured neuro-sphere cells and promote regeneration of injured spinal cord
    • Wu, S., Suzuki, Y., Ejiri, Y., Noda, T., Bai, H., Kitada, M., Kataoka, K., Ohta, M., Chou, H., and Ide, C. Bone marrow stromal cells enhance differentiation of cocultured neuro-sphere cells and promote regeneration of injured spinal cord. J Neurosci Res 72, 343, 2003.
    • (2003) J Neurosci Res , vol.72 , pp. 343
    • Wu, S.1    Suzuki, Y.2    Ejiri, Y.3    Noda, T.4    Bai, H.5    Kitada, M.6    Kataoka, K.7    Ohta, M.8    Chou, H.9    Ide, C.10
  • 11
    • 21244477905 scopus 로고    scopus 로고
    • Protective effects of bone marrow stromal cell transplantation in injured rodent brain: Synthe-sis of neurotrophic factors
    • Chen, Q., Long, Y., Yuan, X., Zou, L., Sun, J., Chen, S., Perez-Polo, J.R., and Yang, K. Protective effects of bone marrow stromal cell transplantation in injured rodent brain: synthe-sis of neurotrophic factors. J Neurosci Res 80, 611, 2005.
    • (2005) J Neurosci Res , vol.80 , pp. 611
    • Chen, Q.1    Long, Y.2    Yuan, X.3    Zou, L.4    Sun, J.5    Chen, S.6    Perez-Polo, J.R.7    Yang, K.8
  • 12
    • 33750550464 scopus 로고    scopus 로고
    • Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia
    • Coyne, T.M., Marcus, A.J., Woodbury, D., and Black, I.B. Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia. Stem Cells 24, 2483, 2006.
    • (2006) Stem Cells , vol.24 , pp. 2483
    • Coyne, T.M.1    Marcus, A.J.2    Woodbury, D.3    Black, I.B.4
  • 14
    • 15844386796 scopus 로고    scopus 로고
    • Upre-gulated gene expression of local brain-derived neurotrophic factor and nerve growth factor after intracisternal adminis-tration of marrow stromal cells in rats with traumatic brain injury
    • Hu, D.Z., Zhou, L.F., Zhu, J., Mao, Y., and Wu, X.H. Upre-gulated gene expression of local brain-derived neurotrophic factor and nerve growth factor after intracisternal adminis-tration of marrow stromal cells in rats with traumatic brain injury. Chin J Traumatol 8, 23, 2005.
    • (2005) Chin J Traumatol , vol.8 , pp. 23
    • Hu, D.Z.1    Zhou, L.F.2    Zhu, J.3    Mao, Y.4    Wu, X.H.5
  • 15
  • 17
    • 0033974706 scopus 로고    scopus 로고
    • Intracerebral transplantation of bone marrow with BDNF after MCAo in rat
    • Chen, J., Li, Y., and Chopp, M. Intracerebral transplantation of bone marrow with BDNF after MCAo in rat. Neuro-pharmacology 39, 711, 2000.
    • (2000) Neuro-pharmacology , vol.39 , pp. 711
    • Chen, J.1    Li, Y.2    Chopp, M.3
  • 18
    • 33846187092 scopus 로고    scopus 로고
    • Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats
    • Urdzikova, L., Jendelova, P., Glogarova, K., Burian, M., Hajek, M., and Sykova, E. Transplantation of bone marrow stem cells as well as mobilization by granulocyte-colony stimulating factor promotes recovery after spinal cord injury in rats. J Neurotrauma 23, 1379, 2006.
    • (2006) J Neurotrauma , vol.23 , pp. 1379
    • Urdzikova, L.1    Jendelova, P.2    Glogarova, K.3    Burian, M.4    Hajek, M.5    Sykova, E.6
  • 19
    • 33750456195 scopus 로고    scopus 로고
    • Combining motor training with transplantation of rat bone marrow stromal cells does not improve repair or recovery in rats with thoracic contusion injuries
    • Yoshihara, H., Shumsky, J.S., Neuhuber, B., Otsuka, T., Fi-scher, I., and Murray, M. Combining motor training with transplantation of rat bone marrow stromal cells does not improve repair or recovery in rats with thoracic contusion injuries. Brain Res 1119, 65, 2006.
    • (2006) Brain Res , vol.1119 , pp. 65
    • Yoshihara, H.1    Shumsky, J.S.2    Neuhuber, B.3    Otsuka, T.4    Fi-Scher, I.5    Murray, M.6
  • 20
    • 5044220530 scopus 로고    scopus 로고
    • Bone marrow transplants provide tissue protection and direc-tional guidance for axons after contusive spinal cord injury in rats
    • Ankeny, D.P., McTigue, D.M., and Jakeman, L.B. Bone marrow transplants provide tissue protection and direc-tional guidance for axons after contusive spinal cord injury in rats. Exp Neurol190, 17, 2004.
    • (2004) Exp Neurol , vol.190 , pp. 17
    • Ankeny, D.P.1    McTigue, D.M.2    Jakeman, L.B.3
  • 21
    • 21244470714 scopus 로고    scopus 로고
    • Immunogenicity of adult mesenchymal stem cells: Lessons from the fetal allograft
    • Barry, F.P., Murphy, J.M., English, K., and Mahon, B.P. Immunogenicity of adult mesenchymal stem cells: lessons from the fetal allograft. Stem Cells Dev 14, 252, 2005.
    • (2005) Stem Cells Dev , vol.14 , pp. 252
    • Barry, F.P.1    Murphy, J.M.2    English, K.3    Mahon, B.P.4
  • 22
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal, S., and Pittenger, M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105, 1815, 2005.
    • (2005) Blood , vol.105 , pp. 1815
    • Aggarwal, S.1    Pittenger, M.F.2
  • 28
    • 0032145723 scopus 로고    scopus 로고
    • Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro
    • Heuckeroth, R.O., Lampe, P.A., Johnson, E.M., and Mil-brandt, J. Neurturin and GDNF promote proliferation and survival of enteric neuron and glial progenitors in vitro. Dev Biol 200, 116, 1998.
    • (1998) Dev Biol , vol.200 , pp. 116
    • Heuckeroth, R.O.1    Lampe, P.A.2    Johnson, E.M.3    Mil-Brandt, J.4
  • 30
    • 0344375091 scopus 로고    scopus 로고
    • Jr. Experimental modeling of spinal cord injury: Characterization of a force-defined injury device
    • Scheff, S.W., Rabchevsky, A.G., Fugaccia, I., Main, J.A., and Lumpp, J.E., Jr. Experimental modeling of spinal cord injury: characterization of a force-defined injury device. J Neuro-trauma 20, 179, 2003.
    • (2003) J Neuro-trauma , vol.20 , pp. 179
    • Scheff, S.W.1    Rabchevsky, A.G.2    Fugaccia, I.3    Main, J.A.4    Lumpp, J.E.5
  • 31
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso, D.M., Beattie, M.S., and Bresnahan, J.C. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 12, 1, 1995.
    • (1995) J Neurotrauma , vol.12 , pp. 1
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 32
    • 0025995529 scopus 로고
    • Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle
    • Mayhew, T.M., and Olsen, D.R. Magnetic resonance imaging (MRI) and model-free estimates of brain volume determined using the Cavalieri principle. J. Anat 178, 133, 1991.
    • (1991) J. Anat , vol.178 , pp. 133
    • Mayhew, T.M.1    Olsen, D.R.2
  • 33
    • 0034983395 scopus 로고    scopus 로고
    • Differences in neuro-trophic factor gene expression profiles between neonate and adult rat spinal cord after injury
    • Nakamura, M., and Bregman, B.S. Differences in neuro-trophic factor gene expression profiles between neonate and adult rat spinal cord after injury. Exp Neurol169, 407, 2001.
    • (2001) Exp Neurol , vol.169 , pp. 407
    • Nakamura, M.1    Bregman, B.S.2
  • 34
    • 11844273931 scopus 로고    scopus 로고
    • BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury
    • Lu, P., Jones, L.L., and Tuszynski, M.H. BDNF-expressing marrow stromal cells support extensive axonal growth at sites of spinal cord injury. Exp Neurol191, 344, 2005.
    • (2005) Exp Neurol , vol.191 , pp. 344
    • Lu, P.1    Jones, L.L.2    Tuszynski, M.H.3
  • 35
    • 0033232045 scopus 로고    scopus 로고
    • Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appro-priate manner that correlates with expression of L1
    • Weidner, N., Blesch, A., Grill, R.J., and Tuszynski, M.H. Nerve growth factor-hypersecreting Schwann cell grafts augment and guide spinal cord axonal growth and remyelinate central nervous system axons in a phenotypically appro-priate manner that correlates with expression of L1. J Comp Neurol 413, 495, 1999.
    • (1999) J Comp Neurol , vol.413 , pp. 495
    • Weidner, N.1    Blesch, A.2    Grill, R.J.3    Tuszynski, M.H.4
  • 36
    • 0028218083 scopus 로고
    • Fibroblasts genetically modi-fied to produce nerve growth factor induce robust neuritic growth after grafting to the spinal cord
    • Tuszynski, M.H., Peterson, D.A., Ray, J., Baird, A., Na-kahara, Y., and Gage, F.H. Fibroblasts genetically modi-fied to produce nerve growth factor induce robust neuritic growth after grafting to the spinal cord. Exp Neurol126,1, 1994.
    • (1994) Exp Neurol126 , vol.1
    • Tuszynski, M.H.1    Peterson, D.A.2    Ray, J.3    Baird, A.4    Na-Kahara, Y.5    Gage, F.H.6
  • 38
    • 0242497104 scopus 로고    scopus 로고
    • Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and in-duces remyelination
    • Blesch, A., and Tuszynski, M.H. Cellular GDNF delivery promotes growth of motor and dorsal column sensory axons after partial and complete spinal cord transections and in-duces remyelination. J Comp Neuro 1467, 403, 2003.
    • (2003) J Comp Neuro , vol.1467 , pp. 403
    • Blesch, A.1    Tuszynski, M.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.