Does a nanomolecule of carboplatin injected periocularly help in attaining higher intravitreal concentrations?

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 12, 2009, Pages 5896-5900

  Shome, Debraj ^a,b   Poddar, Neha ^c   Sharma, Vinay ^c   Sheorey, Uday ^c   Maru, Girish B ^a   Ingle, Arvind ^a   Sarin, Rajiv ^a   Banavali, Shripad ^a   Dikshit, Rajesh ^a   Jain, Vandana ^d   Honavar, Santosh ^e   Bellare, Jayesh ^c  

^a TATA MEMORIAL HOSPITAL   (India)

^b APOLLO HOSPITAL   (India)

^c INDIAN INSTITUTE OF TECHNOLOGY BOMBAY   (India)

^d ADITYA JYOT EYE HOSPITAL PVT LTD   (India)

^e L V PRASAD EYE INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; CARBOPLATIN; NANOPARTICLE; DRUG CARRIER; NANOCAPSULE;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DOSAGE FORM COMPARISON; DRUG TISSUE LEVEL; DRUG TRANSPORT; ELECTRON MICROSCOPY; INFRARED SPECTROSCOPY; LIGHT SCATTERING; NONHUMAN; PARTICLE SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; VITREOUS BODY; ANIMAL; BIOAVAILABILITY; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INJECTION; METABOLISM; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; TRANSMISSION ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANIMALS; BIOLOGICAL AVAILABILITY; CARBOPLATIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CARRIERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; INJECTIONS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOCAPSULES; RATS; RATS, SPRAGUE-DAWLEY; SERUM ALBUMIN, BOVINE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE DISTRIBUTION; VITREOUS BODY;

EID: 73349128114     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-3914     Document Type: Article

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