-
2
-
-
33747598945
-
Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase
-
Austin, et al. (2006) Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase. Nat Chem Biol 2:494-502.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 494-502
-
-
Austin1
-
3
-
-
33947662068
-
Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids
-
Gokhale, et al. (2007) Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids. Nat Prod Rep 24:267-277.
-
(2007)
Nat Prod Rep
, vol.24
, pp. 267-277
-
-
Gokhale1
-
4
-
-
0042975166
-
Natural products-A simple model to explain chemical diversity
-
Firn RD, Jones CG (2003) Natural products-A simple model to explain chemical diversity. Nat Prod Rep 20:382-391.
-
(2003)
Nat Prod Rep
, vol.20
, pp. 382-391
-
-
Firn, R.D.1
Jones, C.G.2
-
5
-
-
0034887171
-
Polyketide biosynthesis: A millennium review
-
Staunton J, Weissman K (2001) Polyketide biosynthesis: A millennium review. Nat Prod Rep 18:380-416.
-
(2001)
Nat Prod Rep
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.2
-
6
-
-
0041412707
-
The structure of docking domains in modular polyketide synthases
-
Broadhurst, et al. (2003) The structure of docking domains in modular polyketide synthases. Chem Biol 10:723-731.
-
(2003)
Chem Biol
, vol.10
, pp. 723-731
-
-
Broadhurst1
-
7
-
-
60749090908
-
Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains
-
Buchholz, et al. (2009) Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. Am Chem Soc Chem Biol 4:41-52.
-
(2009)
Am Chem Soc Chem Biol
, vol.4
, pp. 41-52
-
-
Buchholz1
-
8
-
-
0033574768
-
Dissecting and exploiting intermodular communication in polyketide synthases
-
Gokhale R, Tsuji S, Cane D, Khosla C (1999) Dissecting and exploiting intermodular communication in polyketide synthases. Science 284:482-485.
-
(1999)
Science
, vol.284
, pp. 482-485
-
-
Gokhale, R.1
Tsuji, S.2
Cane, D.3
Khosla, C.4
-
9
-
-
34848923372
-
The origins of specificity in polyketide synthase protein interactions
-
Thattai M, Burak Y, Shraiman B (2007) The origins of specificity in polyketide synthase protein interactions. PLoS Comput Biol 3:e186.
-
(2007)
PLoS Comput Biol
, vol.3
-
-
Thattai, M.1
Burak, Y.2
Shraiman, B.3
-
10
-
-
0035957047
-
Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules
-
Tsuji SY, Cane DE, Khosla C (2001) Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules. Biochemistry 40:2326-2331.
-
(2001)
Biochemistry
, vol.40
, pp. 2326-2331
-
-
Tsuji, S.Y.1
Cane, D.E.2
Khosla, C.3
-
11
-
-
22144436255
-
Theoretical considerations and computational analysis of the complexity in polyketide synthesis pathways
-
Gonzalez-Lergier J, Broadbelt LJ, Hatzimanikatis V (2005) Theoretical considerations and computational analysis of the complexity in polyketide synthesis pathways. J Am Chem Soc 127:9930-9938.
-
(2005)
J Am Chem Soc
, vol.127
, pp. 9930-9938
-
-
Gonzalez-Lergier, J.1
Broadbelt, L.J.2
Hatzimanikatis, V.3
-
12
-
-
29944438701
-
Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster
-
Menzella, et al. (2006) Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster. J Ind Microbiol Biotechnol 33:22-28.
-
(2006)
J Ind Microbiol Biotechnol
, vol.33
, pp. 22-28
-
-
Menzella1
-
13
-
-
34250704344
-
Combinatorial biosynthesis for drug development
-
Menzella H, Reeves C (2007) Combinatorial biosynthesis for drug development. Curr Opin Microbiol 10:238-245.
-
(2007)
Curr Opin Microbiol
, vol.10
, pp. 238-245
-
-
Menzella, H.1
Reeves, C.2
-
14
-
-
34247279292
-
Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes
-
Minowa Y, Araki M, Kanehisa M (2007) Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes. J Mol Biol 368:1500-1517.
-
(2007)
J Mol Biol
, vol.368
, pp. 1500-1517
-
-
Minowa, Y.1
Araki, M.2
Kanehisa, M.3
-
16
-
-
0035058359
-
Evolution of prokaryotic gene order: Genome rearrangements in closely related species
-
Suyama M, Bork P (2001) Evolution of prokaryotic gene order: Genome rearrangements in closely related species. Trends Genet 17:10-13.
-
(2001)
Trends Genet
, vol.17
, pp. 10-13
-
-
Suyama, M.1
Bork, P.2
-
17
-
-
0010414313
-
-
Tamames J (2001) Evolution of gene order conservation in prokaryotes. Genome Biology 10.1186/gb-2001-2-6-research0020.
-
Tamames J (2001) Evolution of gene order conservation in prokaryotes. Genome Biology 10.1186/gb-2001-2-6-research0020.
-
-
-
-
19
-
-
0029847554
-
Selfish operons: Horizontal transfer may drive the evolution of gene clusters
-
Lawrence JG, Roth JR (1996) Selfish operons: Horizontal transfer may drive the evolution of gene clusters. Genetics 143:1843-1860.
-
(1996)
Genetics
, vol.143
, pp. 1843-1860
-
-
Lawrence, J.G.1
Roth, J.R.2
-
20
-
-
33750428183
-
Natural biocombinatorics in the polyketide synthase genes of the actinobacterium Streptomyces avermitilis
-
Jenke-Kodama H, Börner T, Dittmann E, Leadly P (2006) Natural biocombinatorics in the polyketide synthase genes of the actinobacterium Streptomyces avermitilis. PLoS Comput Biol 2:e132.
-
(2006)
PLoS Comput Biol
, vol.2
-
-
Jenke-Kodama, H.1
Börner, T.2
Dittmann, E.3
Leadly, P.4
-
21
-
-
0036731845
-
Molecular evolution of aromatic polyketides and comparative sequence analysis of polyketide ketosynthase and 16S ribosomal DNA genes from various streptomyces species
-
Metsa-Ketela, et al. (2002) Molecular evolution of aromatic polyketides and comparative sequence analysis of polyketide ketosynthase and 16S ribosomal DNA genes from various streptomyces species. Appl Environ Microbiol 68:4472-4479.
-
(2002)
Appl Environ Microbiol
, vol.68
, pp. 4472-4479
-
-
Metsa-Ketela1
-
22
-
-
61349112079
-
From fitness landscapes to seascapes: Non-equilibrium dynamics of selection and adaptation
-
Mustonen V, Lassig M (2009) From fitness landscapes to seascapes: Non-equilibrium dynamics of selection and adaptation. Trends Genet 25:111-119.
-
(2009)
Trends Genet
, vol.25
, pp. 111-119
-
-
Mustonen, V.1
Lassig, M.2
-
23
-
-
0002027029
-
A new evolutionary law
-
Van Valen L (1973) A new evolutionary law. Evol Theory 1:1-30.
-
(1973)
Evol Theory
, vol.1
, pp. 1-30
-
-
Van Valen, L.1
-
24
-
-
0031127243
-
Deleterious mutations, variable epistatic interactions, and the evolution of recombination
-
Otto SP, Feldman MW (1997) Deleterious mutations, variable epistatic interactions, and the evolution of recombination. Theor Popul Biol 51:134-147.
-
(1997)
Theor Popul Biol
, vol.51
, pp. 134-147
-
-
Otto, S.P.1
Feldman, M.W.2
-
25
-
-
0030457013
-
Population genetic perspectives on the evolution of recombination
-
Feldman MW, Otto SP, Christiansen FB (1996) Population genetic perspectives on the evolution of recombination. Annu Rev Genet 30:261-295.
-
(1996)
Annu Rev Genet
, vol.30
, pp. 261-295
-
-
Feldman, M.W.1
Otto, S.P.2
Christiansen, F.B.3
-
27
-
-
66149145312
-
Competition between recombination and epistasis can cause a transition from allele to genotype selection
-
Neher R, Shraiman BI (2009) Competition between recombination and epistasis can cause a transition from allele to genotype selection. Proc Natl Acad Sci USA 106:6866-6871.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 6866-6871
-
-
Neher, R.1
Shraiman, B.I.2
-
28
-
-
67249086022
-
-
Simon-Loriere, et al. (2009) Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus. PLoS Pathog 5:e1000418.
-
Simon-Loriere, et al. (2009) Molecular mechanisms of recombination restriction in the envelope gene of the human immunodeficiency virus. PLoS Pathog 5:e1000418.
-
-
-
-
30
-
-
0017864518
-
Molecular genetics of bacteriophage P22
-
Susskind M, Botstein D (1978) Molecular genetics of bacteriophage P22. Microbiol Rev 42:385.
-
(1978)
Microbiol Rev
, vol.42
, pp. 385
-
-
Susskind, M.1
Botstein, D.2
-
31
-
-
0019231684
-
A theory of modular evolution for bacteriophages
-
Botstein D (1980) A theory of modular evolution for bacteriophages. Ann NY Acad Sci 354:484-491.
-
(1980)
Ann NY Acad Sci
, vol.354
, pp. 484-491
-
-
Botstein, D.1
-
33
-
-
0030777211
-
Highly variable mutation rates in commensal and pathogenic Escherichia coli
-
Matic, et al. (1997) Highly variable mutation rates in commensal and pathogenic Escherichia coli. Science 277:1833-1834.
-
(1997)
Science
, vol.277
, pp. 1833-1834
-
-
Matic1
-
34
-
-
17844407663
-
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example
-
McAlpine, et al. (2005) Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example. J Nat Prod 68:493-496.
-
(2005)
J Nat Prod
, vol.68
, pp. 493-496
-
-
McAlpine1
-
35
-
-
0034716946
-
Genomic sequences of bacteriophages HK97 and HK022: Pervasive genetic mosaicism in the lambdoid bacteriophages
-
Juhala, et al. (2000) Genomic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages. J Mol Biol 299:27-51.
-
(2000)
J Mol Biol
, vol.299
, pp. 27-51
-
-
Juhala1
-
36
-
-
42449155111
-
The evolution of gene collectives: How natural selection drives chemical innovation
-
Fischbach M, Walsh C, Clardy J (2008) The evolution of gene collectives: How natural selection drives chemical innovation. Proc Natl Acad Sci USA 105:4601-4608.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4601-4608
-
-
Fischbach, M.1
Walsh, C.2
Clardy, J.3
|