Prospective study of methotrexate treatment for rheumatoid arthritis treated legitimately according to the government recommended 8 mg/week dose

Modern Rheumatology

Volumn 19, Issue 6, 2009, Pages 637-642

  Hashiramoto, Akira ^a   Shiozawa, Kazuko ^b   Tanaka, Yasushi ^b   Yamane, Takashi ^b   Murata, Miki ^b   Tanaka, Chihiro ^a,b   Terashima, Yasuhiro ^b   Koyama, Kozo ^b   Nakagawa, Natsuko ^b   Abe, Shuji ^b   Yoshihara, Rhosuke ^b   Saegusa, Yasuhiro ^c   Tsumiyama, Ken ^d   Komai, Koichiro ^d   Sakai, Yoshitada ^a   Shiozawa, Shunichi ^a  

^a KOBE UNIVERSITY HOSPITAL   (Japan)

^b Konan Kakogawa Hospital   (Japan)

^c Konan Hospital   (Japan)

^d KOBE UNIVERSITY   (Japan)

Author keywords

ACR core set; DAS 28; EULAR response; Methotrexate; Rheumatoid arthritis

Indexed keywords

C REACTIVE PROTEIN; METHOTREXATE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL TRIAL; DISEASE SEVERITY; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG FEVER; DRUG MEGADOSE; DRUG SAFETY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; INTERSTITIAL PNEUMONIA; JAPANESE; LEUKOPENIA; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECOMMENDED DRUG DOSE; RESPIRATORY TRACT DISEASE; RHEUMATOID ARTHRITIS; TREATMENT DURATION; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; METHOTREXATE; MIDDLE AGED; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 73349122297     PISSN: 14397595     EISSN: 14397609     Source Type: Journal    
DOI: 10.1007/s10165-009-0205-x     Document Type: Article

References (22)

1. NJ Olsen CM Stein 2004 New drugs for rheumatoid arthritis N Engl J Med 350 2167 2179 10.1056/NEJMra032906 1:CAS:528:DC%2BD2cXktF2isL4%3D 15152062 (Pubitemid 38637997)
2. JM Kremer 2001 Rational use of new and existing disease modifying agents in rheumatoid arthritis Ann Intern Med 138 695 706
3. RT Hoffmeister 1983 Methotrexate therapy in rheumatoid arthritis: 15-year experience Am J Med 75 69 73 10.1016/0002-9343(83)90477-1 1:STN:280: DyaL2c7gtFGhsw%3D%3D 6660241
4. ME Weinblatt JS Coblyn DA Fox PA Fraser DE Holdsworth DN Glass, et al. 1985 Efficacy of low-dose methotrexate in rheumatoid arthritis N Engl J Med 312 818 822 1:STN:280:DyaL2M7jslOmtw%3D%3D 3883172
5. JM Kremer JK Lee 1986 The safety and efficacy of the use of methotrexate in long-term therapy for rheumatoid arthritis Arthritis Rheum 29 822 831 10.1002/art.1780290702 1:STN:280:DyaL283psF2htg%3D%3D 3741499
6. JM Kremer 1997 Safety, efficacy, and mortality in a long-term cohort of patients with rheumatoid arthritis taking methotrexate: followup after a mean of 13.3 years Arthritis Rheum 40 984 985 10.1002/art.1780400533 1:STN:280:DyaK2s3psl2gtg%3D%3D 9153566
7. ME Weinblatt AL Maier PA Fraser JS Colyn 1998 Longterm prospective study of methotrexate in rheumatoid arthritis: conclusions after 132 months of therapy J Rheumatol 25 238 242 1:CAS:528:DyaK1cXhtVGgu7w%3D 9489813
8. H Yamanaka E Inoue E Tanaka A Nakajima A Taniguchi C Terai, et al. 2007 Influence of methotrexate dose on its efficacy and safety in rheumatoid arthritis patients: evidence based on the variety of prescribing approaches among practicing Japanese rheumatologists in a single institute-based large observational cohort (IORRA) Mod Rheumatol 17 98 105 10.1007/s10165-006-0546-7 1:CAS:528:DC%2BD2sXktlSmsb8%3D 17437163 (Pubitemid 46614352)
9. H Yamanaka E Inoue G Singh E Tanaka A Nakajima A Taniguchi, et al. 2007 Improvement of disease activity of rheumatoid arthritis patients from 2000 to 2006 in a large observational cohort study IORRA in Japan Mod Rheumatol 17 283 289 10.1007/s10165-007-0587-6 17694260 (Pubitemid 47263818)
10. FC Arnett SM Edworthy DA Bloch DJ McShane JF Fries NS Cooper, et al. 1988 The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 315 324 10.1002/art.1780310302 1:STN:280:DyaL1c7pt1Ohsg%3D%3D 3358796
11. G Baron P Ravaud A Samson B Giraudeau 2008 Missing data in randomized controlled trials of rheumatoid arthritis with radiographic outcomes; a simulation study Arthritis Rheum 59 25 31 10.1002/art.23253 18163406 (Pubitemid 351171875)
12. DAS-score NL. Home of the DAS. Available at: http://www.das-score.nl/.
13. E Inoue H Yamanaka M Hara T Tomatsu N Kamatani 2007 Comparison of Disease Activity Score (DAS)28-erythrocyte sedimentation rate and DAS28-C-reactive protein threshold values Ann Rheum dis 66 407 409 10.1136/ard.2006.054205 1:CAS:528:DC%2BD2sXjvFSht7o%3D 16926186 (Pubitemid 46579645)
14. D van der Heijde 2000 How to read radiographs according to the Sharp/van der Heijde method J Rheumatol 27 261 263 10648051
15. MF Bakker JW Jacobs SM Verstappen JW Bijlsma 2007 Tight control in the treatment of rheumatoid arthritis: efficacy and feasibility Ann Rheum Dis 66 Suppl 3 56 60
16. ET Molenaar AE Voskuyl HJ Dinant PD Bezemer M Boers BA Dijkmans 2004 Progression of radiologic damage in patients with rheumatoid arthritis in clinical remission Arthritis Rheum 50 36 42 10.1002/art.11481 14730597 (Pubitemid 38084285)
17. D van der Heijde L Klareskog R Landewé GA Bruyn A Cantagrel P Durez, et al. 2007 Disease remission and sustained halting of radiographic progression with combination etanercept and methotrexate in patients with rheumatoid arthritis Arthritis Rheum 56 3928 3939 10.1002/art.23141 18050208 (Pubitemid 350262318)
18. J Swierkot J Szechiński 2006 Methotrexate in rheumatoid arthritis Pharmacol Rep 58 473 492 1:CAS:528:DC%2BD28XhtlarsbnN 16963793
19. CM Lambert S Sandhu A Lochhead NP Hurst E McRorie V Dhillon 2004 Dose escalation of parenteral methotrexate in active rheumatoid arthritis that has been unresponsive to conventional doses of methotrexate: a randomized, controlled trial Arthritis Rheum 50 364 371 10.1002/art.20167 1:CAS:528:DC%2BD2cXhvFeitb4%3D 14872477 (Pubitemid 38198819)
20. AE van Ede RF Laan HJ Blom RA De Abreu LB van de Putte 1998 Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity Semin Arthritis Rheum 27 277 292 10.1016/S0049-0172(98)80049-8 9572710 (Pubitemid 28176234)
21. S Inokuma T Sato A Sagawa T Matsuda T Takemura T Ohtsuka, et al. 2008 Proposals for leflunomide use to avoid lung injury in patients with rheumatoid arthritis Mod Rheumatol 18 442 446 10.1007/s10165-008-0088-2 1:CAS:528:DC%2BD1cXht1anu7rJ 18551351
22. AS Russell 2008 Quality-of-life assessment in rheumatoid arthritis Pharmacoeconomics 26 831 846 10.2165/00019053-200826100-00004 1:CAS:528:DC%2BD1cXhsVWltrzF 18793031