Pediatric celiac disease

Current Opinion in Pediatrics

Volumn 21, Issue 5, 2009, Pages 655-660

  Zawahir, Shamila ^a   Safta, Anca ^a   Fasano, Alessio ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Autoimmunity; Celiac disease; Gluten free diet

Indexed keywords

ALGORITHM; CELIAC DISEASE; CHILDHOOD DISEASE; DIAGNOSTIC PROCEDURE; DUODENUM BIOPSY; EARLY INTERVENTION; ENDOSCOPY; GLUTEN FREE DIET; HIGH RISK INFANT; HUMAN; PATHOGENESIS; PATIENT COMPLIANCE; PRIORITY JOURNAL; REVIEW;

ADOLESCENT; AGE FACTORS; CELIAC DISEASE; CHILD; DIET, GLUTEN-FREE; ENDOSCOPY; HUMANS; PATIENT COMPLIANCE;

EID: 73349120889     PISSN: 10408703     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOP.0b013e32832f5b9d     Document Type: Review

References (34)

1. Guandalini S. Historical perspective of celiac disease. In: Fasano A, Troncone R, Branski D, editors. Frontiers in celiac disease. vol 12. Basel, Karger; 2008. pp. 1-11.
2. Catassi C, Yachha S. The global village of celiac disease. In: Fasano A, Troncone R, Branski D, editors. Frontiers in celiac disease. vol 12. Basel, Karger; 2008. pp. 23-31.
3. Nistico L, Fagnani C, Coto I, et al. Concordance, disease progression, and heritability of celiac disease in Italian twins. Gut 2006; 55:803-808.
4. Wouters J, Weijerman M, van Furth M, et al. Prospective human leukocyte antigen, endomysium immunoglobulin A antibodies, and transglutaminase antibody testing for celiac disease in children with Down syndrome. J Pediatr 2009; 154:239-242.
5. Korponay-Szabo IR, Dahlbom I, Laurila K, et al. Elevation of IgG antibodies against tissue transglutaminase as a diagnostic tool for coeliac disease in selective IgA deficiency. Gut 2003; 52:1567-1571.
6. Gianfrani C, Troncone R, La Cava A. Autoimmunity and celiac disease. Mini Rev Med Chem 2008; 8:129-134. A review of the autoimmune disorders associated with celiac disease, the pathogenesis of celiac disease as well as a discussion of future therapeutic options.
7. Leeds J, Hopper A, Sanders D. Coeliac disease. Br Med Bull 2008; 88:157-170.
8. Cassinotti A, Birindelli S, CLerici M, et al. HLA and autoimmune digestive disease: a clinical oriented review for gastroenterologists. Am J Gastroenterol 2009; 104:195-217. This is an in-depth review of the HLA genetics involved in celiac disease including their clinical implications.
9. Catassi C, Fasano A. Celiac disease. Curr Opin Gastroenterol 2008; 24: 687-691. This article is an in-depth discussion of the current role of genetics in the pathogenesis of celiac disease as well as novel therapeutic options.
10. Garrote JA, Gomez-Gonzalez E, Bernardo D, et al. Celiac disease pathogenesis: the pro-inflammatory cytokine network. J Pediatr Gastroenterol Nutr 2008; 47:S27-S32. This article comprehensively discusses the involvement of the innate immune system in the pathogenesis of celiac disease outlining the involvement of various cytokines and their interactions.
11. Branski D, Fasano A, Troncone R. Latest developments in the pathogenesis and treatment of celiac disease. J Pediatrics 2006; 149:295-300.
12. Lebenthal E, Shteyer E, Branski D. The changing clinical presentation of celiac disease. In: Fasano A, Troncone R, Branski D, editors. Frontiers in celiac disease. vol 12. Basel, Karger; 2008. pp. 18-22. This study illustrates the changing spectrum in the presentation of celiac disease highlighting the many extra-intestinal and nonspecific findings.
13. Kurppa K, Koskinen O, Collin P, et al. Changing phenotype of celiac disease after long-standing gluten exposure. J Pediatr Gastroenterol Nutr 2008; 47:500-503.
14. Grossman G. Neurological complications of celiac disease: what is the evidence? Pract Neurol 2008; 8:77-89. An in-depth review of the evidence supporting associations of neurological symptoms with celiac disease.
15. Campanella J, Biagi F, Bianchi P, et al. Clinical response to gluten withdrawal is not an indicator of coeliac disease. Scand J Gastroenterol 2008; 43:1311-1314. This study describes the response of disorders other than celiac disease to withdrawal of gluten from the diet, thereby lending support to the practice of not modifying the diet until histological diagnosis is made.
16. Volta U, Granito A, Fiorini E, et al. Usefulness of antibodies to deamidated gliadin peptides in Celiac disease dagnosis and follow-up. Dig Dis Sci 2008; 53:1582-1588. This study demonstrated the higher sensitivity for celiac disease than AGA antibodies. Also it showed that persistence of positive values was associated with persistent mucosal damage.
17. Caicedo R, Hill I. Current guideline for the diagnosis and treatment of celiac disease. In: Fasano A, Troncone R, Branski D, editors. Frontiers in celiac disease. vol 12. Basel, Karger; 2008. pp. 107-113. The study systematically goes through the evidence behind the current recommendations for screening, diagnosis, and management of celiac disease.
18. Lagerqvist C, Dahlbom I, Hansson T, et al. Antigliadin immunoglobulin A best in finding celiac disease in children younger than 18 months of age. J Pediatr Gastroenterol Nutr 2008; 47:428-435. This study shows that transglutaminase and endomysial antibodies are not reliable screening tools in children under the age of 18 months. It demonstrates that AGA antibodies may be successfully used in this population.
19. Green P, Lee S. Endoscopy in celiac disease. Curr Opin Gastroenterol 2005; 21:589-594.
20. Dickey W. Endoscopic markers for celiac disease. Nat Clin Pract Gastroenterol Hepatol 2006; 3:546-551.
21. Pais W, Duerkson D, Pettigrew N, Bernstein C. How many duodenal biopsy specimens are required to make a diagnosis of celiac disease? Gastrointest Endosc 2008; 67:1082-1087. This study gives evidence that in order to increase the confidence of providing histological evidence of celiac disease, four duodenal biopsies should be taken.
22. Bonamico M, Thanasi E, Mariani P, et al. Duodenal bulb biopsies in celiac disease: a multicenter study. J Pediatr Gastroenterol Nutr 2008; 47:618-622. This multicenter study demonstrated the patchy nature of the disease highlighting that diagnostic findings are always found in the bulb. This study supports the practice of multiple biopsies from multiple sites including the bulb of the duodenum.
23. Memeo L, Jhang J, Hibshoosh H, et al. Duodenal intraepithelial lymphocytosis with normal villous architecture: common occurrence in H. pylori gastritis. Mod Pathol 2005; 18:1134-1144.
24. Walker M, Talley N, Prabhakar M, et al. Duodenal mastocytosis, eosinophilia and intraepithelial lymphocytosis as possible disease markers in the irritable bowel syndrome and functional dyspepsia. Aliment Pharmacol Ther 2009; 29:765-773.
25. Vande Voort J, Murray J, Lahr B, et al. Lymphocytic duodenosis and the spectrum of celiac disease. Am J Gastroenterol 2009; 104:142-148.
26. Kurppa K, Collin P, Viljamaa M, et al. Diagnosing mild enteropathy celiac disease: a randomized, controlled clinical study. Gastroenterology 2009; 136:816-823. This study showed that in patients with positive endomysial antibodies and lowlevel mucosal damage, benefit was obtained from the GFD.
27. Ersoy O, Akin E, Ugras S, et al. Capsule endoscopy findings in celiac disease. Dig Dis Sci 2009; 54:825-829. This study shows that visual findings may be apparent in celiac disease using VCE, but it provides no diagnostic contribution to celiac disease in contrast to conventional endoscopy.
28. Sachdev M, Ismail M. Capsule endoscopy: a review. South Med J 2008; 101:407-414.
29. Cohen M. Barnard J. The National Institutes of Health consensus conference report. In: Fasano A, Troncone R, Branski D, editors. Frontiers in celiac disease. vol 12. Basel, Karger; 2008. pp. 133-138. This is a concise summary of the recommendations of the NIH regarding the approach to diagnosis and management of celiac disease as well as recommendations for the education of healthcare providers and standardizing care.
30. Troncone R, Auricchio R, Granata V. Issues related to gluten-free diet in celiac disease. Curr Opin Clin Nutr Metab Care 2008; 11:329-333. A review of the management of the GFD as well as threshold allowances in a GFD. It also addresses the role of diet modification in silent and latent celiac diseases.
31. Fabiani E, Taccari L, Ratsch I, et al. Compliance with gluten-free diet in adolescents with screening-detected celiac disease: a 5 year follow-up. J Pediatrics 2000; 136:841-843.
32. Catassi C, Fabiani E, Iacono G, et al. A prospective, double-blinded, placebocontrolled trial to establish a safe gluten threshold for patients with celiac disease. Am J Clin Nutr 2007; 85:160-166.
33. Yachha S, Srivastava A, Mohindra S, et al. Effect of a gluten-free diet on growth and small-bowel histology in children with celiac disease in India. J Gastroenterol Hepatol 2007; 22:1300-1305.
34. Agostini C, Decsi T, Fewtrell M, et al. Complementary feeding: a commentary by ESPGHAN committee on nutrition. J Pediatr Gastroenterol Nutr 2008; 46:99-110. This study addresses the existing evidence behind recommendations for gluten introduction into the diet of infants. It also discusses the relationship between breastfeeding and risk for celiac disease.