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Volumn 73, Issue 24, 2009, Pages 2052-2053

APOE ε4 and bapineuzumab: Infusing pharmacogenomics into Alzheimer disease therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; BAPINEUZUMAB; IMMUNOGLOBULIN G; PLACEBO; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; MONOCLONAL ANTIBODY;

EID: 73349117170     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181c6784a     Document Type: Editorial
Times cited : (19)

References (10)
  • 1
    • 0007691164 scopus 로고
    • Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease
    • Poirier J, Delisle MC, Quirion R, et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer disease. Proc Natl Acad Sci USA 1995;92:12260-12264.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 12260-12264
    • Poirier, J.1    Delisle, M.C.2    Quirion, R.3
  • 2
    • 0029665096 scopus 로고    scopus 로고
    • Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease
    • Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN. Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease. Am J Pathol 1996;148: 2083-2095.
    • (1996) Am J Pathol , vol.148 , pp. 2083-2095
    • Premkumar, D.R.1    Cohen, D.L.2    Hedera, P.3    Friedland, R.P.4    Kalaria, R.N.5
  • 3
    • 0033536163 scopus 로고    scopus 로고
    • Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
    • Schenk D, Barbour R, Dunn W, et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 1999;400:173-177.
    • (1999) Nature , vol.400 , pp. 173-177
    • Schenk, D.1    Barbour, R.2    Dunn, W.3
  • 4
    • 10744230547 scopus 로고    scopus 로고
    • Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization
    • Orgogozo JM, Gilman S, Dartigues JF, et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 2003;61:46-54.
    • (2003) Neurology , vol.61 , pp. 46-54
    • Orgogozo, J.M.1    Gilman, S.2    Dartigues, J.F.3
  • 5
    • 73349091534 scopus 로고    scopus 로고
    • A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
    • Salloway S, Sperling R, Gilman S, et al. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 2009;73:2061-2070.
    • (2009) Neurology , vol.73 , pp. 2061-2070
    • Salloway, S.1    Sperling, R.2    Gilman, S.3
  • 6
    • 36248941497 scopus 로고    scopus 로고
    • Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice
    • Petrushina I, Ghochikyan A, Mktrichyan M, et al. Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Abeta species in amyloid precursor protein transgenic mice. J Neurosci 2007;27:12721-12731.
    • (2007) J Neurosci , vol.27 , pp. 12721-12731
    • Petrushina, I.1    Ghochikyan, A.2    Mktrichyan, M.3
  • 8
    • 33745266146 scopus 로고    scopus 로고
    • Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
    • Risner ME, Saunders AM, Altman JF, et al. Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease. Pharmacogenomics J 2006;6:246-254.
    • (2006) Pharmacogenomics J , vol.6 , pp. 246-254
    • Risner, M.E.1    Saunders, A.M.2    Altman, J.F.3
  • 9
    • 1242338801 scopus 로고    scopus 로고
    • Effects of beta-hydroxybutyrate on cognition in memory-impaired adults
    • Reger MA, Henderson ST, Hale C, et al. Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiol Aging 2004;3:311-314.
    • (2004) Neurobiol Aging , vol.3 , pp. 311-314
    • Reger, M.A.1    Henderson, S.T.2    Hale, C.3
  • 10
    • 65249158083 scopus 로고    scopus 로고
    • Understanding the association of apolipoprotein E4 with Alzheimer disease: Clues from its structure
    • Zhong N, Weisgraber KH. Understanding the association of apolipoprotein E4 with Alzheimer disease: clues from its structure. J Biol Chem 2009;284:6027-6031.
    • (2009) J Biol Chem , vol.284 , pp. 6027-6031
    • Zhong, N.1    Weisgraber, K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.