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Volumn 18, Issue 6, 2009, Pages 489-494

Lymphocyte markers and prediction of long-term renal allograft acceptance

Author keywords

Immune monitoring; Rejection; Tolerance; Transplantation

Indexed keywords

BIOLOGICAL MARKER; CALCINEURIN INHIBITOR; IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; STEROID; T LYMPHOCYTE RECEPTOR; VIRUS ANTIGEN;

EID: 73349107808     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e3283318f82     Document Type: Review
Times cited : (12)

References (58)
  • 3
    • 32844458509 scopus 로고    scopus 로고
    • + lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients
    • + lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients. J Am Soc Nephrol 2006; 17:294-304.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 294-304
    • Baeten, D.1    Louis, S.2    Braud, C.3
  • 4
    • 33646820310 scopus 로고    scopus 로고
    • Perforin, Granzyme B, and fas ligand for molecular diagnosis of acute renal-allograft rejection: Analyses on serial biopsies suggest methodological issues
    • Graziotto R, Del Prete D, Rigotti P, et al. Perforin, Granzyme B, and fas ligand for molecular diagnosis of acute renal-allograft rejection: analyses on serial biopsies suggest methodological issues. Transplantation 2006; 81:1125-1132.
    • (2006) Transplantation , vol.81 , pp. 1125-1132
    • Graziotto, R.1    Del Prete, D.2    Rigotti, P.3
  • 6
    • 65249177814 scopus 로고    scopus 로고
    • Predominant Th 1 and cytotoxic phenotype in biopsies from renal transplant recipients with transplant glomerulopathy
    • This study demonstrates the role of T-cell mediated inflammatory/ cytotoxic processes in the pathogenesis of transplant glomerulopathy.
    • Homs S, Mansour H, Desvaux D, et al. Predominant Th 1 and cytotoxic phenotype in biopsies from renal transplant recipients with transplant glomerulopathy. Am J Transplant 2009; 9:1230-1236. This study demonstrates the role of T-cell mediated inflammatory/cytotoxic processes in the pathogenesis of transplant glomerulopathy.
    • (2009) Am J Transplant , vol.9 , pp. 1230-1236
    • Homs, S.1    Mansour, H.2    Desvaux, D.3
  • 8
    • 56249146391 scopus 로고    scopus 로고
    • Intragraft levels of Foxp3 mRNA predict progression in renal transplants with borderline change
    • This study suggests that Foxp3 mRNA exression is a useful predictive marker of borderline histologic changes in renal transplant patients.
    • Mansour H, Homs S, Desvaux D, et al. Intragraft levels of Foxp3 mRNA predict progression in renal transplants with borderline change. J Am Soc Nephrol 2008; 19:2277-2281. This study suggests that Foxp3 mRNA exression is a useful predictive marker of borderline histologic changes in renal transplant patients.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 2277-2281
    • Mansour, H.1    Homs, S.2    Desvaux, D.3
  • 10
    • 59649110032 scopus 로고    scopus 로고
    • A novel role of CD4 Th 17 cells in mediating cardiac allograft rejection and vasculopathy
    • Yuan X, Paez-Cortez J, Schmitt-Knosalla I, et al. A novel role of CD4 Th 17 cells in mediating cardiac allograft rejection and vasculopathy. J Exp Med 2008; 205:3133-3144. This is the first study demonstrating the role of TH 17 in the development of allograft rejection in the absence of Th1 -mediated alloimmunity.
    • (2008) J Exp Med , vol.205 , pp. 3133-3144
    • Yuan, X.1    Paez-Cortez, J.2    Schmitt-Knosalla, I.3
  • 11
    • 56149107712 scopus 로고    scopus 로고
    • CD8- Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deflcient mice
    • Burrell BE, Csencsits K, Lu G, et al. CD8- Th17 mediate costimulation blockade-resistant allograft rejection in T-bet-deflcient mice. J Immunol 2008; 181:3906-3914.
    • (2008) J Immunol , vol.181 , pp. 3906-3914
    • Burrell, B.E.1    Csencsits, K.2    Lu, G.3
  • 15
    • 33748857907 scopus 로고    scopus 로고
    • Sequential gene expression profiling in lung transplant recipients with chronic rejection
    • DOI 10.1378/chest.130.3.847
    • Lu BS, Yu AD, Zhu X, et al. Sequential gene expression profiling in lung transplant recipients with chronic rejection. Chest 2006; 130:847-854. (Pubitemid 44423619)
    • (2006) Chest , vol.130 , Issue.3 , pp. 847-854
    • Lu, B.S.1    Yu, A.D.2    Zhu, X.3    Garrity Jr., E.R.4    Vigneswaran, W.T.5    Bhorade, S.M.6
  • 18
    • 48749084927 scopus 로고    scopus 로고
    • Using transcriptional profiling to develop a diagnostic test of operational tolerance in liver transplant recipients
    • Martínez-Llordella M, Lozano JJ, Puig-Pey I, et al. Using transcriptional profiling to develop a diagnostic test of operational tolerance In liver transplant recipients. J Clin Invest 2008; 118:2845-2857. The data of the study demonstrate transcriptional profiling of peripheral blood that can be employed to identify liver transplant recipients appropriate for the discontinuation of immunosuppressive therapy.
    • (2008) J Clin Invest , vol.118 , pp. 2845-2857
    • Martínez-Llordella, M.1    Lozano, J.J.2    Puig-Pey, I.3
  • 19
    • 33644610514 scopus 로고    scopus 로고
    • Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling
    • Deng MC, Eisen HJ, Mehra MR, et al. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am J Transplant 2006; 6:150-160.
    • (2006) Am J Transplant , vol.6 , pp. 150-160
    • Deng, M.C.1    Eisen, H.J.2    Mehra, M.R.3
  • 20
    • 40649093305 scopus 로고    scopus 로고
    • Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection
    • Mehra MR, Kobashigawa JA, Deng MC, et al. Clinical implications and longitudinal alteration of peripheral blood transcriptional signals indicative of future cardiac allograft rejection. J Heart Lung Transplant 2008; 27:297-301.
    • (2008) J Heart Lung Transplant , vol.27 , pp. 297-301
    • Mehra, M.R.1    Kobashigawa, J.A.2    Deng, M.C.3
  • 21
    • 74549220832 scopus 로고    scopus 로고
    • This study applied a previously established transcriptional profile using 11 distinct genes for prediction of cardiac allograft rejection weeks to months prior to the actual event. The authors were able to separate patients early after transplantation into low-risk, intermediate-risk or high-risk categories for future rejection.
    • This study applied a previously established transcriptional profile using 11 distinct genes for prediction of cardiac allograft rejection weeks to months prior to the actual event. The authors were able to separate patients early after transplantation into low-risk, intermediate-risk or high-risk categories for future rejection.
  • 22
    • 41849131031 scopus 로고    scopus 로고
    • Immunosuppressive drug-free operational immune tolerance in human kidney transplant recipients. Part I. Blood gene expression statistical analysis
    • Braud C, Baeten D, Giral M, et al. Immunosuppressive drug-free operational immune tolerance In human kidney transplant recipients. Part I. Blood gene expression statistical analysis. J Cell Biochem 2008; 103:1681-1692.
    • (2008) J Cell Biochem , vol.103 , pp. 1681-1692
    • Braud, C.1    Baeten, D.2    Giral, M.3
  • 23
    • 74549203968 scopus 로고    scopus 로고
    • This study demonstrates a unique peripheral blood mononuclear cell gene signature associated with human operational tolerance In kidney transplant patients using the expression pattern of 343 genes.
    • This study demonstrates a unique peripheral blood mononuclear cell gene signature associated with human operational tolerance In kidney transplant patients using the expression pattern of 343 genes.
  • 24
    • 34249052267 scopus 로고    scopus 로고
    • Posttransplant monitoring of pediatric lung transplant recipients
    • DOI 10.1097/MOP.0b013e3280991205, PII 0000848020070600000015
    • Visner GA, Goldfarb SB. Posttransplant monitoring of pediatric lung transplant recipients. Curr Opin Pediatr 2007; 19:321-326. (Pubitemid 46788120)
    • (2007) Current Opinion in Pediatrics , vol.19 , Issue.3 , pp. 321-326
    • Visner, G.A.1    Goldfarb, S.B.2
  • 26
    • 34548385742 scopus 로고    scopus 로고
    • Immunodiagnostics: Evaluation of functional T-cell immunocompetence in whole blood independent of circulating cell numbers
    • DOI 10.1080/15476910701385638, PII 781829779
    • Kowalski RJ, Zeevi A, Mannon RB, et al. Immunodiagnostics: evaluation of functional T-cell immnocompetence in whole blood independent of circulating cell numbers. J immunotoxlcol 2007; 4:225-232. (Pubitemid 47360098)
    • (2007) Journal of Immunotoxicology , vol.4 , Issue.3 , pp. 225-232
    • Kowalski, R.J.1    Zeevi, A.2    Mannon, R.B.3    Britz, J.A.4    Carruth, L.M.5
  • 27
    • 34250328218 scopus 로고    scopus 로고
    • Preceeding the rejection: In search for a comprehensive post-transplant immune monitoring platform
    • DOI 10.1016/j.trim.2007.03.005, PII S0966327407000755
    • Israeli M, Yussim A, Mor E, et al. Preceeding the rejection: in search for a comprehensive posttransplant immune monitoring platform. Transpl Immunol 2007; 18:7-12. (Pubitemid 46920968)
    • (2007) Transplant Immunology , vol.18 , Issue.1 , pp. 7-12
    • Israeli, M.1    Yussim, A.2    Mor, E.3    Sredni, B.4    Klein, T.5
  • 28
    • 0033566737 scopus 로고    scopus 로고
    • Pretransplant frequency of donor-specific, IFN-γ-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes
    • Heeger PS, Greenspan NS, Kuhlenschmidt S, et al. Pretransplant frequency of donor-specific, IFN-g-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol 1999; 163:2267-2275. (Pubitemid 29382237)
    • (1999) Journal of Immunology , vol.163 , Issue.4 , pp. 2267-2275
    • Heeger, P.S.1    Greenspan, N.S.2    Kuhlenschmidt, S.3    Dejelo, C.4    Hricik, D.E.5    Schulak, J.A.6    Tary-Lehmann, M.7
  • 31
    • 33751422386 scopus 로고    scopus 로고
    • Modified ELISPOT technique - Highly significant inverse correlation of post-Tx donor-reactive IFNγ-producing cell frequencies with 6 and 12months graft function in kidney transplant recipients
    • DOI 10.1016/j.trim.2006.09.026, PII S0966327406001341
    • Näther BJ, Nickel P, Bold G, et al. Modified ELISPOT technique: highly significant inverse correlation of post-Tx donor-reactive IFN-γ-producing cell frequencies with 6 and 12 months graft function in kidney transplant recipients. Transpl Immunol 2006; 16:232-237. (Pubitemid 44816482)
    • (2006) Transplant Immunology , vol.16 , Issue.3-4 , pp. 232-237
    • Nather, B.J.1    Nickel, P.2    Bold, G.3    Presber, F.4    Schonemann, C.5    Pratschke, J.6    Volk, H.-D.7    Reinke, P.8
  • 32
    • 10644278692 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12 months in renal-transplant recipients
    • DOI 10.1097/01.TP.0000144057.31799.6A
    • Nickel P, Presber F, Bold G, et al. Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-produclng cells identifies T-cell presensituation and correlates with graft function at 6 and 12 months in renaltransplant recipients. Transplantation 2004; 78:1640-1646. (Pubitemid 39648437)
    • (2004) Transplantation , vol.78 , Issue.11 , pp. 1640-1646
    • Nickel, P.1    Presber, F.2    Bold, G.3    Biti, D.4    Schonemann, C.5    Tullius, S.G.6    Volk, H.-D.7    Reinke, P.8
  • 33
    • 48149108073 scopus 로고    scopus 로고
    • Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients
    • Bestard O, Nickel P, Cruzado JM, et al. Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients. J Am Soc Nephrol 2008; 19:1419-1429.
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1419-1429
    • Bestard, O.1    Nickel, P.2    Cruzado, J.M.3
  • 34
    • 74549132938 scopus 로고    scopus 로고
    • This study demonstrates for the first time that circulating donor-specific alloreactive T cells primed by direct and indirect allorecognition pathways are detectable long after transplantation and are associated with graft injury.
    • This study demonstrates for the first time that circulating donor-specific alloreactive T cells primed by direct and indirect allorecognition pathways are detectable long after transplantation and are associated with graft injury.
  • 36
    • 37049010274 scopus 로고    scopus 로고
    • Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients
    • Kim SH, Oh EJ, Kim MJ, et al. Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients. Transplant Proc 2007; 39:3057-3060.
    • (2007) Transplant Proc , vol.39 , pp. 3057-3060
    • Kim, S.H.1    Oh, E.J.2    Kim, M.J.3
  • 37
    • 41149157985 scopus 로고    scopus 로고
    • Pretransplant donor-specific and nonspecific immune parameters associated with early acute rejection
    • The data of the study showed that HLA class I mismatches, total HLA mismatches, pretransplant HLA-donor specific antibodies as well as higher pretransplant iATP levels were associated with biopsy-proven acute rejection
    • Reinsmoen NL, Cornett KMM, Kloehn R, et al. Pretransplant donor-specific and nonspecific immune parameters associated with early acute rejection. Transplantation 2008; 85:462-470. The data of the study showed that HLA class I mismatches, total HLA mismatches, pretransplant HLA-donor specific antibodies as well as higher pretransplant iATP levels were associated with biopsy-proven acute rejection.
    • (2008) Transplantation , vol.85 , pp. 462-470
    • Reinsmoen, N.L.1    Cornett, K.M.M.2    Kloehn, R.3
  • 38
    • 33645455798 scopus 로고    scopus 로고
    • Identification of dialysis patients with panel-reactive memory T cells before kidney transplantation using an allogeneic cell bank
    • Andree H, Nickel P, Nasiadko C, et al. Identification of dialysis patients with panel-reactive memory T cells before kidney transplantation using an allogeneic cell bank. J Am Soc Nephrol 2006; 17:573-580.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 573-580
    • Andree, H.1    Nickel, P.2    Nasiadko, C.3
  • 39
    • 33645456450 scopus 로고    scopus 로고
    • Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates
    • Poggio ED, Clemente M, Hricik DE, et al. Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates. J Am Soc Nephrol 2006; 17:564-572.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 564-572
    • Poggio, E.D.1    Clemente, M.2    Hricik, D.E.3
  • 40
    • 23044487610 scopus 로고    scopus 로고
    • The direct and indirect allogeneic presentation pathway during acute rejection after human cardiac transplantation
    • Van Besouw NM, Zuijderwujk JM, Vaessen LM, et al. The direct and indirect allogeneic presentation pathway during acute rejection after human cardiac transplantation. Clin Exp Immunol 2005; 141:534-540.
    • (2005) Clin Exp Immunol , vol.141 , pp. 534-540
    • Van Besouw, N.M.1    Zuijderwujk, J.M.2    Vaessen, L.M.3
  • 41
    • 0035893012 scopus 로고    scopus 로고
    • Loss of direct and maintenance of indirect alloresponses in renal allograft recipients: Implications for the pathogenesis of chronic allograft nephropathy
    • Baker RJ, Hernandez-Fuentes MP, Brookes PA, et al. Loss of direct and maintenance of indirect alloresponses in renal allograft recipients: implications for the pathogenesis of chronic allograft nephropathy. J Immunol 2001; 167:7199-7206.
    • (2001) J Immunol , vol.167 , pp. 7199-7206
    • Baker, R.J.1    Hernandez-Fuentes, M.P.2    Brookes, P.A.3
  • 42
    • 58849141233 scopus 로고    scopus 로고
    • An assessment of herpesvirus coinfections in patients with CMV disease: Correlation with clinical and virologie outcomes
    • Humar A, Asberg A, Kumar D, et al. An assessment of herpesvirus coinfections in patients with CMV disease: correlation with clinical and virologie outcomes. Am J Transplant 2009; 9:374-381.
    • (2009) Am J Transplant , vol.9 , pp. 374-381
    • Humar, A.1    Asberg, A.2    Kumar, D.3
  • 43
    • 0035959321 scopus 로고    scopus 로고
    • Association between Epstein-Barr virus infection and late acute transplant rejection in long-term transplant patients
    • Babel N, Schwarzmann F, Prang N, et al. Association between Epstein-Barr virus infection and late acute transplant rejection in long-term transplant patients. Transplantation 2001; 72:736-739. (Pubitemid 32802763)
    • (2001) Transplantation , vol.72 , Issue.4 , pp. 736-739
    • Babel, N.1    Schwarzmann, F.2    Prang, N.3    Jaeger, M.4    Wolf, H.5    Kern, F.6    Volk, H.D.7    Reinke, P.8
  • 44
    • 65549088504 scopus 로고    scopus 로고
    • Prospective monitoring of Epstein-Barr virus DNA in adult renal transplant recipients during the early posttransplant period: Role of mycophenolate mofetil
    • Holmes MV, Caplin B, Atkinson C, et al. Prospective monitoring of Epstein-Barr virus DNA in adult renal transplant recipients during the early posttransplant period: role of mycophenolate mofetil. Transplantation 2009; 87:852-856.
    • (2009) Transplantation , vol.87 , pp. 852-856
    • Holmes, M.V.1    Caplin, B.2    Atkinson, C.3
  • 45
    • 67651021382 scopus 로고    scopus 로고
    • Sustained BK viruria as an early marker for the development of BKV-associated nephropathy: Analysis of 4128 urine and serum samples
    • Babel N, Fendt J, Karaivanov S, et al. Sustained BK viruri a as an early marker for the development of BKV-associated nephropathy: analysis of 4128 urine and serum samples. Transplantation 2009; 88:89-95.
    • (2009) Transplantation , vol.88 , pp. 89-95
    • Babel, N.1    Fendt, J.2    Karaivanov, S.3
  • 47
    • 77954173564 scopus 로고    scopus 로고
    • CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: A pilot study
    • [Epub ahead of print]
    • Sund F, Lidehäll AK, Claesson K, et al. CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study. Clin Transplant 2009 [Epub ahead of print]
    • (2009) Clin Transplant
    • Sund, F.1    Lidehäll, A.K.2    Claesson, K.3
  • 49
    • 59649125190 scopus 로고    scopus 로고
    • High levels of CMV-IE-1 -specific memory T cells are associated with less alloimmunity and improved renal allograft function
    • Nickel P, Bold G, Presber F, et al. High levels of CMV-IE-1 -specific memory T cells are associated with less alloimmunity and improved renal allograft function. Transpl Immunol 2009; 20:238-242.
    • (2009) Transpl Immunol , vol.20 , pp. 238-242
    • Nickel, P.1    Bold, G.2    Presber, F.3
  • 50
    • 56749130944 scopus 로고    scopus 로고
    • Monitoring of Epstein-Barr virus load and killer T cells in pediatric renal transplant recipients
    • Sato T, Fujieda M, Maeda A, et al. Monitoring of Epstein-Barr virus load and killer T cells In pediatric renal transplant recipients. Clin Nephrol 2008; 70:393-403.
    • (2008) Clin Nephrol , vol.70 , pp. 393-403
    • Sato, T.1    Fujieda, M.2    Maeda, A.3
  • 52
    • 33847199387 scopus 로고    scopus 로고
    • Quantitative analysis of EBV-specific CD4/CD8 T cell numbers, absolute CD4/CD8 T cell numbers and EBV load in solid organ transplant recipients with PLTD
    • DOI 10.1016/j.trim.2006.10.006, PII S0966327406001444
    • Sebelin-Wulf K, Nguyen TD, Oertel S, et al. Quantitative analysis of EBV-specific CD4/CD8 T cell numbers, absolute CD4/CD8 T cell numbers and EBV load in solid organ transplant recipients with PLTD. Transpl Immunol 2007; 17:203-210. (Pubitemid 46304228)
    • (2007) Transplant Immunology , vol.17 , Issue.3 , pp. 203-210
    • Sebelin-Wulf, K.1    Nguyen, T.D.2    Oertel, S.3    Papp-Vary, M.4    Trappe, R.U.5    Schulzki, A.6    Pezzutto, A.7    Riess, H.8    Subklewe, M.9
  • 57
    • 33644929967 scopus 로고    scopus 로고
    • HLA type-independent method to monitor polyoma BK virus-specific CD4 and CD8 T-cell immunity
    • Hammer MH, Brestrich G, Andree H, et al. HLA type-independent method to monitor polyoma BK virus-specific CD4 and CD8 T-cell immunity. Am J Transplant 2006; 6:625-631.
    • (2006) Am J Transplant , vol.6 , pp. 625-631
    • Hammer, M.H.1    Brestrich, G.2    Andree, H.3
  • 58
    • 42549130945 scopus 로고    scopus 로고
    • Does reduction in immunosuppression in viremic patients prevent BK virus nephropathy in de novo renal transplant recipients? A prospective study
    • DOI 10.1097/TP.0b013e31816a33d4, PII 0000789020080427000008
    • Aimeras C, Foulongne V, Garrigue V, et al. Does reduction in immunosuppression in viremic patients prevent BK virus nephropathy in de novo renal transplant recipients? A prospective study. Transplantation 2008; 85:1099-1104. (Pubitemid 351590186)
    • (2008) Transplantation , vol.85 , Issue.8 , pp. 1099-1104
    • Almeras, C.1    Foulongne, V.2    Garrigue, V.3    Szwarc, I.4    Vetromile, F.5    Segondy, M.6    Mourad, G.7


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