Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research: Trade-off between sensitivity and specificity with change of test cut-offs

Journal of Clinical Pathology

Volumn 62, Issue 11, 2009, Pages 1051-

  Bharti, Bhavneet ^a   Bharti, Sahul ^b  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

^b Khuda Ali Sher ^*  (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

DIAGNOSTIC TEST; LETTER; MEDICAL PRACTICE; MEDICAL RESEARCH; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY;

BIOLOGICAL MARKERS; DIAGNOSTIC TECHNIQUES AND PROCEDURES; HUMANS; PROGNOSIS; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 73349101530     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2009.069591     Document Type: Letter

References (3)

1. Søreide K. Receiver-operating characteristic curve analysis in diagnostic, prognostic and predictive biomarker research. J Clin Pathol 2009;62:1-5.
2. Leeflang MMG, Moons KGM, Reitsma JB, et al. Bias in sensitivity and specificity caused by data-driven selection of optimal cutoff values: mechanisms, magnitude, and solutions. Clin Chem 2008;54:729-37.
3. Guyatt G, Sackett D, Haynes B. Evaluation of diagnostic tests. In: Haynes RB, Sackett D, Guyatt GH, et al, eds. Clinical epidemiology: how to do clinical practice research. Lippincott Williams & Wilkins, 2006:273-322.