Pathological and microbiological studies of Japanese hare (Lepus brachyurus angustidens) naturally infected with Francisella tularensis subsp. holarctica

Journal of Veterinary Medical Science

Volumn 71, Issue 12, 2009, Pages 1629-1635

  Park, Chun Ho ^a   Nakanishi, Ataru ^a   Hatai, Hitoshi ^a   Kojima, Daisuke ^a   Oyamada, Toshifumi ^a   Sato, Hisaaki ^a   Kudo, Noboru ^a   Shindo, Junji ^a   Fujita, Osamu ^b   Hotta, Akitoyo ^b   Inoue, Satoshi ^b   Tanabayashi, Kiyoshi ^b  

^a KITASATO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Histopathology; Japanese hare (Lepus brachyurus angustidens); Tularemia (yato byo)

Indexed keywords

BACTERIUM ANTIBODY;

ANIMAL; ANIMAL DISEASE; ARTICLE; CASE REPORT; FRANCISELLA TULARENSIS; HARE; INSECT BITE; JAPAN; LIVER; MALE; MICROBIOLOGY; PATHOLOGY; SKIN; TICK; TULAREMIA;

ANIMALS; ANTIBODIES, BACTERIAL; FRANCISELLA TULARENSIS; HARES; INSECT BITES AND STINGS; JAPAN; LIVER; MALE; SKIN; TICKS; TULAREMIA;

BACTERIA (MICROORGANISMS); FRANCISELLA TULARENSIS; FRANCISELLA TULARENSIS SUBSP. HOLARCTICA; IXODIDA; LEPUS BRACHYURUS; LEPUS BRACHYURUS ANGUSTIDENS; MONIA;

EID: 73349095414     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.001629     Document Type: Article

References (31)

1. Baldwin, C. J., Panciera, R. J., Morton, R. J., Cowell, A. K. and Waurzyniak, B. J. 1991. Acute tularemia in three domestic cats. J. Am. Vet. Med. Assoc. 199: 1602-1605.
2. Broekhuijsen, M., Larsson, P., Johansson, A., Byström, M., Eriksson, U., Larsson, E., Prior, R. G., Sjöstedt, A., Titball, R. W. and Forsman, M. 2003. Genome-wide DNA microarray analysis of Francisella tularensis strains demonstrates extensive genetic conservation within the species but identifies regions that are unique to the highly virulent F. tularensis subsp. tularensis. J. Clin. Microbiol. 41: 2924-2931.
3. Clemens, D. L. and Horwitz, M. A. 2007. Uptake and intracellular fate of Francisella tularensis in human macrophages. Ann. New York Acad. Sci. 1105: 160-186.
4. DeBey, B. M., Andrews, G. A., Chard-Bergstrom, C. and Cox, L. 2002. Immunohistochemical demonstration of Francisella tularensis in lesions of cats with tularemia. J. Vet. Diagn. Invest. 14: 162-164.
5. Eliasson, H., Lindbäck, J., Nuorti, J. P., Arneborn, M., Giesecke, J. and Tegnell, A. 2002. The 2000 tularemia out-break: a case-control study of risk factors in disease-endemic and emergent areas, Sweden. Emerg. Infect. Dis. 8: 956-960.
6. Ellis, J., Oyston, P. C., Green, M. and Titball, R. W. 2002. Tularemia. Clin. Microbiol. Rev. 15: 631-646.
7. Evans, M. E. 1985. Francisella tularensis. Infect. Control 6: 381-383.
8. Forsman, M., Sandström, G. and Sjöstedt, A. 1994. Analysis of 16S ribosomal DNA sequences of Francisella strains and utilization for determination of the phylogeny of the genus and for identification of strains by PCR. Int. J. Syst. Bacteriol. 44: 38-46.
9. Fujita, O., Tatsumi, M., Tanabayashi, K. and Yamada, A. 2006. Development of a real-time PCR assay for detection and quantification of Francisella tularensis. Jpn J. Infect. Dis. 59: 46-51.
10. Fujita, O., Uda, A., Hotta, A., Okutani, A., Inoue, S., Tanabayashi, K. and Yamada, A. 2008. Genetic diversity of Francisella tularensis subspecies holarctica strains isolated in Japan. Microbiol. Immunol. 52: 270-276.
11. Fulop, M., Leslie, D. and Titball, R. 1996. A rapid, highly sensitive method for the detection of Francisella tularensis in clinical samples using the polymerase chain reaction. Am. J. Trop. Med. Hyg. 54: 364-366.
12. Gerasimov, V. N., Dolotov, V. I., Stepanov, A. V. and Urakov, N. N. 1997. Morphology, ultrastructure and populational features of bacteria Francisella. Vestn. Ross. Akad. Med. Nauk. 6: 24-30.
13. Goethert, H. K., Shani, I. and Telford, S. R. 3rd. 2004. Genotypic diversity of Francisella tularensis infecting Dermacentor variabilis ticks on Martha's Vineyard, Massachusetts. J. Clin. Microbiol. 42: 4968-4973.
14. Gurner, J., Greer, P. W., Bartlett, J., Chu, M. C., Shieh, W. and Zaki, S. R. 1999. Immunohistochemical detection of Francisella tularensis in formalin-fixed paraffin-embedded tissue. Appl. Immunohistochem. Mol. Morphol. 7: 122-126.
15. Gustafson, B. W. and DeBowes, L. J. 1996. Tularemia in a dog. J. Am. Anim. Hosp. Assoc. 32: 339-341.
16. Hotta, A., Uda, A., Fujita, O., Tanabayashi, K. and Yamada, A. 2007. Preparation of monoclonal antibodies for detection and identification of Francisella tularensis. Clin. Vaccine Immunol. 14: 81-84.
17. Johansson, A., Farlow, J., Larsson, P., Dukerich, M., Chambers, E., Byström, M., Fox, J., Chu, M., Forsman, M., Sjöstedt, A. and Keim, P. 2004. Worldwide genetic relationships among Francisella tularensis isolates determined by multiple-locus variable-number tandem repeat analysis. J. Bacteriol. 186: 5808-5818.
18. Kemenes, F. 1976. Die epizootologie der hasen tularämie in Ungarn. pp. 285-289. In: Proceedings 2: Internationales Arbeitskolloquium über "Naturherds von Infektionskrankheiten in Zentraleuropa", Graz, Austria (in German).
19. Kugeler, K. J., Gurfield, N., Creek, J. G., Mahoney, K. S., Versage J. L. and Petersen, J. M. 2005. Discrimination between Francisella tularensis and Francisella-like endosymbionts when screening ticks by PCR. Appl. Environ. Microbiol. 71: 7594-7597.
20. Mörner, T. and Addison, E. 2001. Tularemia. pp. 303-312. In: Infectious Diseases of Wild Mammals, 3rd ed. (Williams, E. S. and Barker, I. K. eds.), Iowa State University Press, Ames.
21. Mörner, T., Sandström, G., Mattsson, R. and Nilsson, P. O. 1988. Infections with Francisella tularensis biovar palaearctica in hares (Lepus timidus, Lepus europaeus) from Sweden. J. Wild Dis. 24: 422-433.
22. Ohara, S. I. 1954. Studies on yato-byo (Ohara's disease, tularemia in Japan), Report I. Jpn J. Exp. Med. 24: 69-79.
23. Ohara, Y., Sato, T. and Homma, M. 1998. Arthropod-borne tularemia in Japan: clinical analysis of 1,374 cases observed between 1924 and 1996. J. Med. Entomol. 35: 471-473.
24. Ohara, Y., Sato, T. and Homma, M. 1996. Epidemiological analysis of tularemia in Japan (yato-byo). FEMS Immunol. Med. Microbiol. 13: 185-189.
25. Olsufjev, N. G. and Meshcheryakova, I. S. 1982. Infraspecific taxonomy of tularemia agent Francisella tularensis McCoy et Chapin. J. Hyg. Epidemiol. Microbiol. Immunol. 26: 291-299.
26. Petersen, J. M. and Schriefer, M. E. 2005. Tularemia: emergence/ re-emergence. Vet. Res. 36: 455-467.
27. Sandström, G., Sjöstedt, A., Forsman, M., Pavlovich, N. V. and Mishankin, B. N. 1992. Characterization and classification of strains of Francisella tularensis isolated in the central Asian focus of the Soviet Union and in Japan. J. Clin. Microbiol. 30: 172-175.
28. Sjöstedt, A., Eriksson, U., Berglund, L. and Tarnvik, A. 1997. Detection of Francisella tularensis in ulcers of patients with tularemia by PCR. J. Clin. Microbiol. 35: 1045-1048.
29. Sterba, F. and Krul, J. 1985. Pathologisch-morphologische untersuchungen zur differentialdiagnose von brucellose, tularämie und psudotuberkulose beim hasen (Lepus europaeus L.). pp. 763-771. In: XVIIth Congress of the International Union of Game Biologists, Brussels, Belgium (in German).
30. Versage, J. L., Severin, D. D., Chu, M. C. and Petersen, J. M. 2003. Development of a multitarget real-time TaqMan PCR assay for enhanced detection of Francisella tularensis in complex specimens. J. Clin. Microbiol. 41: 5492-5499.
31. Zeidner, N. S., Carter, L. G., Monteneiri, J. A., Petersen, J. M., Schriefer, M., Gage, K. L., Hall, G. and Chu, M. C. 2004. An outbreak of Francisella tularensis in captive prairie dogs: an immunohistochemical analysis. J. Vet. Diagn. Invest. 16: 150-152.