Impaired development of somatotropes, lactotropes and thyrotropes in growth-retarded (grt) mice

Journal of Toxicologic Pathology

Volumn 22, Issue 3, 2009, Pages 187-194

  Kobayashi, Kenichi ^a,b   Yamamoto, Kazutoshi ^c   Kikuyama, Sakae ^c   Machida, Takeo ^a   Kobayashi, Tetsuya ^a  

^a SAITAMA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF OCCUPATIONAL SAFETY AND HEALTH   (Japan)

^c WASEDA UNIVERSITY   (Japan)

Author keywords

Anterior pituitary; grt mouse; Lactotrope; Somatotrope; Thyrotrope

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL MATURATION; CONTROLLED STUDY; DEVELOPMENTAL BIOLOGY; EXPERIMENTAL MOUSE; GROWTH HORMONE SECRETING CELL; GROWTH RETARDATION; HORMONE BLOOD LEVEL; HORMONE RELEASE; HYPOPHYSIS; IMMUNOREACTIVITY; MALE; MOUSE; NEUROENDOCRINE SYSTEM; NONHUMAN; PROLACTIN SECRETING CELL; TSH SECRETING CELL;

EID: 73349088708     PISSN: 09149198     EISSN: None     Source Type: Journal    
DOI: 10.1293/tox.22.187     Document Type: Article

References (42)

1. Ojeda SR. The anterior pituitary and hypothalamus. In: Textbook of Endocrine Physiology, 5th ed. JE Griffin and SR Ojeda (eds.). Oxford University Press, New York. 120-146. 2004.
2. Snell GD. Dwarf, a new Mendelian recessive character of the house mouse. Proc Nat Acad Sci USA. 15: 733-734. 1929.
3. Shaible R and Gowen JW. A new dwarf mouse. Genetics. 16: 896. 1961.
4. Ingraham HA, Albert VR, Chen RP, Crenshaw 3d EB, Elsholtz HP, He X, Kapiloff MS, Mangalam HJ, Swanson LW, Treacy MN, and Rosenfeld MG. A family of POU-domain and Pit-1 tissue-specific transcription factors in pituitary and neuroendocrine development. Annu Rev Physiol. 52: 773-791. 1990.
5. Karin M, Theill L, Castrillo J-L, McCormic A, and Brady H. Tissue-specific expression of the growth hormone gene and its control by growth hormone factor-1. Rec Prog Horm Res. 46: 43-58. 1990.
6. Beamer WG, Eicher EM, Maltais LJ, and Southard JL. Inherited primary hypothyroidism in mice. Science. 212: 61-63. 1981.
7. Koto M, Sato T, Okamoto M, and Adachi J. rdw rats, a new hereditary dwarf model in the rat. Jikken Dobutsu. 37: 21-30 (in Japanese). 1988.
8. Stein SA, Oates EL, Hall CR, Grumbles RM, Fernandez LM, Taylor NA, Puett D, and Jin S. Identification of a point mutation in the thyrotropin receptor of the hyt/hyt hypothyroid mouse. Mol Endocrinol. 8: 129-138. 1994.
9. Gu WX, Du GG, Kopp P, Rentoumis A, Albanese C, Kohn LD, Madison LD, and Jameson JL. The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding. Endocrinology. 136: 3146-3153. 1995.
10. Noguchi T, Kudo M, Sugisaki T, and Satoh I. An immunocytochemical and electron microscopic study of the hyt mouse anterior pituitary gland. J Endocrinol. 109: 163-168. 1986.
11. Stein SA, Shanklin DR, Krulich L, Roth MG, Chubb CM, and Adams PM. Evaluation and characterization of the hyt/hyt hypothyroid mouse. II. Abnormalities of TSH and the thyroid gland. Neuroendocrinology. 49: 509-519. 1989.
12. 4) in hereditary dwarf rats (rdw/rdw). Jikken Dobutsu. 42: 211-216. 1993.
13. Furudate S, Ono M, Shibayama K, Ohyama Y, Kuwada M, Kimura T, and Kameya T. Rescue from dwarfism by thyroid function compensation in rdw rats. Exp Anim. 54: 455-460. 2005.
14. Umezu M, Kagabu S, Jiang J, and Sato E. Evaluation and characterization of congenital hypothyroidism in rdw dwarf rats. Lab Anim Sci. 48: 496-501. 1998.
15. Sakai Y, Yamashina S, and Furudate S. Missing secretory granules, dilated endoplasmic reticulum, and nuclear dislocation in the thyroid gland of rdw rats with hereditary dwarfism. Anat Rec. 259: 60-66. 2000.
16. Yoshida T, Yamanaka K, Atsumi S, Tsumura H, Sasaki R, Tomita K, Ishikawa E, Ozawa H, Watanabe K, and Totsuka T. A novel hypothyroid 'growth-retarded' mouse derived from Snell's dwarf mouse. J Endocrinol. 142: 435-446. 1994.
17. Tomita K, Yoshida T, Morita J, Atsumi S, and Totsuka T. In vivo responsiveness of thyroid glands to TSH in normal and novel 'growth-retarded' mice: transient elevation in normal mice and impairment in 'growth-retarded' mice. J Endocrinol. 144: 209-214. 1995.
18. Sasaki N, Hosoda Y, Nagata A, Ding M, Cheng JM, Miyamoto T, Okano S, Asano A, Miyoshi I, and Agui T. A mutation in Tpst2 encoding tyrosylprotein sulfotransferase causes dwarfism associated with hypothyroidism. Mol Endocrinol. 21: 1713-1721. 2007.
19. Kobayashi K, Yamamoto H, Kobayashi T, and Machida T. Responses of the thyroid gland to TSH and other thyroid stimulators in the growth-retarded (grt) mouse. Zoolog Sci. 18: 955-961. 2001.
20. Kobayashi K, Kubota H, and Saegusa J. Testicular development in growth-retarded mice. Exp Anim. 56: 393-397. 2007.
21. Kobayashi K, Kubota H, and Saegusa J. Ovarian and uterine development in growth-retarded mice. Exp Anim. 57: 253. 2008.
22. Hosoda Y, Sasaki N, and Agui T. Female infertility in grt mice is caused by thyroid hormone deficiency, not by insufficient TPST2 activity in the reproductive organs. J Vet Med Sci. 70: 1043-1049. 2008.
23. Yamamoto K, and Kikuyama S. Radioimmunoassay of prolactin in plasma of bullfrog tadpoles. Endocrinol Jpn. 29: 159-167. 1982.
24. Ozawa H. Changing ultrastructure of thyrotrophs in the rat anterior pituitary after thyroidectomy as studied by immunoelectron microscopy and enzyme cytochemistry. Cell Tissue Res. 263: 405-412. 1991.
25. Childs GV, Taub K, Jones KE, and Chin WW. Triiodothyronine receptor beta-2 messenger ribonucleic acid expression by somatotropes and thyrotropes: effect of propylthiouracil-induced hypothyroidism in rats. Endocrinology. 129: 2767-2773. 1991.
26. Yamanouchi H, Kitauchi S, and Shiino M. Changes in prolactin secretion in postnatal rats and effect of neonatal thyroidectomy. Mol Cell Endocrinol. 134: 101-107. 1997.
27. Kirby JD, Jetton AE, Cooke PS, Hess RA, Bunick D, Ackland JF, Turek FW, and Schwartz NB. Developmental hormonal profiles accompanying the neonatal hypothyroidism-induced increase in adult testicular size and sperm production in the rat. Endocrinology. 131: 559-565. 1992.
28. Li S, Crenshaw III EB, Rawson EJ, Simmons DM, Swanson LW, and Rosenfeld MG. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature. 347: 528-533. 1990.
29. Bartke A. Histology of the anterior hypophysis, thyroid, gonads of two types of dwarf mice. Anat Rec. 149: 225-235. 1964.
30. Wilson DB, and Wyatt DP. Immunocytochemical effects of thyroxine stimulation on the adenohypophysis of dwarf (dw) mutant mice. Cell Tissue Res. 274: 579-585. 1993.
31. Sinha YN, Salocks CB, and Vanderlaan WP. Pituitary and serum concentrations of prolactin and GH in Snell dwarf mice. Proc Soc Exp Biol Med. 150: 207-210. 1975.
32. Sonntag WE, Steger RW, Forman LJ, and Meites J. Decreased pulsatile release of growth hormone in old male rats. Endocrinology. 107: 1875-1989. 1980.
33. Bartke A, Hafiez AA, Bex FJ, and Dalterio S. Hormonal interactions in regulation of androgen secretion. Biol Reprod. 18: 44-54. 1978.
34. Steger RW, Chandrashekar V, Zhao W, Bartke A, and Horseman ND. Neuroendocrine and reproductive functions in male mice with targeted disruption of the prolactin gene. Endocrinology. 139: 3691-3695. 1998.
35. Griffin JE. The Thyroid. In: Textbook of Endocrine Physiology, 5th ed. Griffin JE and Ojeda SR. Oxford University Press, New York. 294-318. 2004.
36. De Gennaro V, Colonna V, Bertora G, Coco CB, Bifano M, Cocchi D, Maggi A, and Muller EE. Hypothalamic pituitary somatotropic function in prepubertal hypothyroid rats: Effect of growth hormone replacement therapy. Proc Soc Exp Biol Med. 196: 432-437. 1991.
37. Lloyd RV, Jin L, Song JY, Terry LC, Horvath E, and Kovacs K. Effects of propylthiouracil on growth hormone and prolactin messenger ribonucleic acids in the rat pituitary. Lab Invest. 62: 347-354. 1990.
38. Rodriguez-Garcia M, Jolin T, Santos A, and Perez-Castillo A. Effect of prenatal hypothyroidism on the developmental regulation of rat pituitary growth hormone and thyrotropin genes. Endocrinology. 136: 4339-4350. 1995.
39. Behringer RR, Mathews LS, Palmiter RD, and Brinster RL. Dwarf mice produced by genetic ablation of growth hormone-expressing cells. Genes Dev. 2: 453-461. 1988.
40. Borrelli E, Heyman RA, Arias C, Sawchenko PE, and Evans RM. Transgenic mice with inducible dwarfism. Nature. 339: 538-541. 1989.
41. Stahl JH, Kendall SK, Brinkmeier ML, Greco TL, Watkins-Chow DE, Campos-Barros A, Lloyd RV, and Camper SA. Thyroid hormone is essential for pituitary somatotropes and lactotropes. Endocrinology. 140: 1884-1892. 1999.
42. Hibasami H, Yoshida T, Totsuka T, Atsumi S, and Nakashima K. Expression of high activity of ornithine decarboxylase and occurrence of unusual chromophobic cells in anterior pituitary gland of a novel growth-retarded strain of mice, grm/grm. Biochim Biophys Acta. 1226: 110-114. 1994.