Efficient adenovirus-mediated gene transfer to gastric tissue by oral administration

Journal of Gene Medicine

Volumn 11, Issue 12, 2009, Pages 1087-1094

  Liu, Xiao Fei ^a   Shi, Yun ^a   Zhang, Jin Yu ^a   Zhuang, Yuan ^a   Jia, Ke Ran ^a   Mao, Xu Hu ^a   Guo, Ying ^a   Liu, Tao ^a   Liu, Zhen ^a   Wu, Chao ^a   Zhang, Wei Jun ^a   Zhou, Wei Ying ^a   Guo, Gang ^a   Zou, Quan Ming ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Gastric epithelial cell; Gene therapy; Gene transfer; Oral administration; Recombinant adenovirus; Stomach

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; RED FLUORESCENT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GASTROINTESTINAL TRACT; GENE EXPRESSION; GENE TRANSFER; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM; STOMACH JUICE; STOMACH MUCOSA; STOMACH PH; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT;

ADENOVIRIDAE; ADMINISTRATION, ORAL; ANIMALS; BETA-GALACTOSIDASE; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTROINTESTINAL TRACT; GENE THERAPY; GENE TRANSFER TECHNIQUES; INTERLEUKIN-17; INTERLEUKIN-6; KIDNEY; LAC OPERON; LUMINESCENT PROTEINS; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STOMACH NEOPLASMS; TRANSGENES;

ADENOVIRIDAE; MUS;

EID: 73249150087     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1397     Document Type: Article

References (18)

1. Tang DC, Zhang J, Toro H, et al. Adenovirus as a carrier for the development of influenza virus-free avian influenza vaccines. Expert Rev Vaccines 2009; 8: 469-481.
2. Breyer B, Jiang W, Cheng H, et al. Adenoviral vector-mediated gene transfer for human gene therapy. Curr Gene Ther 2001; 1: 149-162.
3. Nadeau I, Kamen A. Production of adenovirus vector for gene therapy. Biotechnol Adv 2003; 20: 475-489.
4. Imperiale MJ, Kochanek S. Adenovirus vectors: biology, design, and production. Curr Top Microbiol Immunol 2004; 273: 335-357.
5. Tatsis N, Ertl HC. Adenoviruses as vaccine vectors. Mol Ther 2004; 10: 616-629.
6. Vorburger SA, Hunt KK. Adenoviral gene therapy. Oncologist 2002; 7: 46-59.
7. Saeki T, Mhashilkar A, Chada S, Branch C, Roth JA, Ramesh R. Tumor-suppressive effects by adenovirus-mediated mda-7 gene transfer in non-small cell lung cancer cell in vitro. Gene Ther 2000; 7: 2051-2057.
8. Haviv YS, Blackwell JL, Kanerva A, et al. Adenoviral gene therapy for renal cancer requires retargeting to alternative cellular receptors. Cancer Res 2002; 62: 4273-4281.
9. Guidotti JE, Mignon A, Haase G, et al. Adenoviral gene therapy of the Tay-Sachs disease in hexosaminidase A-deficient knockout mice. Hum Mol Genet 1999; 8: 831-838.
10. Tucker SN, Tingley DW, Scallan CD. Oral adenoviral-based vaccines: historical perspective and future opportunity. Expert Rev Vaccines 2008; 7: 25-31.
11. Luo J, Deng ZL, Luo X, et al. A protocol for rapid generation of recombinant adenoviruses using the AdEasy system. Nat Protoc 2007; 2: 1236-1247.
12. Garhart CA, Redline RW, Nedrud JG, Czinn SJ. Clearance of Helicobacter pylori infection and resolution of postimmunization gastritis in a kinetic study of prophylactically immunized mice. Infect Immun 2002; 70: 3529-3538.
13. Lagrange M, Boulade-Ladame C, Orfanoudakis G, Deryckere F. Modification of adenovirus type 5 tropism for a preferential transduction of human papillomavirus-positive cancer cells. Arch Virol 2008; 153: 1921-25.
14. Mizuguchi H, Hayakawa T. Targeted adenovirus vectors. Hum Gene Ther 2004; 15: 1034-1044.
15. Huard J, Lochmuller H, Acsadi G, Jani A, Massie B, Karpati G. The route of administration is a major determinant of the transduction efficiency of rat tissues by adenoviral recombinants. Gene Ther 1995; 2: 107-115.
16. Cichon G, Schmidt HH, Benhidjeb T, et al. Intravenous administration of recombinant adenoviruses causes thrombocytopenia, anemia and erythroblastosis in rabbits. J Gene Med 1999; 1: 360-371.
17. Matsukura N, Hoshino A, Igarashi T, et al. In situ gene transfer and suicide gene therapy of gastric cancer induced by N-ethyl- N′-nitro-N-nitrosoguanidine in dogs. Jpn J Cancer Res 1999; 90: 1039-1049.
18. Favier AL, Burmeister WP, Chroboczek J. Unique physicochemical properties of human enteric Ad41 responsible for its survival and replication in the gastrointestinal tract. Virology 2004; 322: 93-104.