Cerebral and systemic hemodynamic effects of intravenous bolus administration of propofol in neonates

Neonatology

Volumn 98, Issue 1, 2010, Pages 57-63

  Vanderhaegen, Joke ^a   Naulaers, Gunnar ^a   Van Huffel, Sabine ^b   Vanhole, Christine ^a   Allegaert, Karel ^a  

^a UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^b Katholieke Universiteit Leuven   (Belgium)

Author keywords

Cerebral tissue oxygenation index; Fractional tissue oxygen extraction; Near infrared spectroscopy; Preterm neonates; Propofol

Indexed keywords

FENTANYL; MIDAZOLAM; OXYGEN; PARACETAMOL; PROPOFOL; TRAMADOL; INTRAVENOUS ANESTHETIC AGENT;

ARTERIAL OXYGEN SATURATION; ARTICLE; BOLUS INJECTION; BRAIN TISSUE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; ELECTIVE SURGERY; FEMALE; FRACTIONAL TISSUE OXYGEN EXTRACTION; GROUPS BY AGE; HEART DISEASE; HEART RATE; HEMODYNAMIC PARAMETERS; HUMAN; INFRARED SPECTROSCOPY; MALE; MEAN ARTERIAL PRESSURE; NEWBORN; NEWBORN CARE; OXYGEN CONSUMPTION; PEDIATRIC ANESTHESIA; PREMATURITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; TISSUE OXYGENATION; TISSUE OXYGENATION INDEX; TUBE REMOVAL; BLOOD; BLOOD PRESSURE; BRAIN; CARDIOVASCULAR SYSTEM; CHEST TUBE; CIRCULATION; DEVICE REMOVAL; DRUG EFFECTS; HEMODYNAMICS; INFANT; VASCULARIZATION;

ANESTHETICS, INTRAVENOUS; BLOOD CIRCULATION; BLOOD PRESSURE; BRAIN; CARDIOVASCULAR SYSTEM; CHEST TUBES; DEVICE REMOVAL; FEMALE; HEART RATE; HEMODYNAMICS; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE; MALE; OXYGEN; OXYGEN CONSUMPTION; PROPOFOL; PROSPECTIVE STUDIES;

EID: 73249147885     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000271224     Document Type: Article

References (31)

1. Allegaert K, de Hoon J, Verbesselt R, Naulaers G, Murat I: Maturational pharmacokinetics of single intravenous bolus of propofol. Paediatr Anaesth 2007; 17: 1028-1034.
2. Allegaert K, Peeters MY, Verbesselt R, Tibboel D, Naulaers G, de Hoon JN, et al: Interindividual variability in propofol pharmacokinetics in preterm and term neonates. Br J Anaesth 2007; 99: 864-870.
3. Papoff P, Mancuso M, Caresta E, Moretti C: Effectiveness and safety of propofol in newborn infants. Pediatrics 2008; 121: 448-449.
4. Ghanta S, Abdel-Latif ME, Lui K, Ravindranathan H, Awad J, Oei J: Propofol compared with the morphine, atropine, and suxamethonium regimen as induction agents for neonatal endotracheal intubation: a randomized, controlled trial. Pediatrics 2007; 119:e1248-e1255. (Pubitemid 46871241)
5. Veyckemans F: Propofol for intubation of the newborn? Paediatr Anaesth 2001; 11:630-631.
6. Naulaers G, Delanghe G, Allegaert K, Debeer A, Cossey V, Vanhole C, et al: Ibuprofen and cerebral oxygenation and circulation. Arch Dis Child Fetal Neonatal Ed 2005; 90: F75-F76.
7. Allegaert K, Naulaers G, Debeer A, Breysem L, Ferens I, Vanhole C, et al: The use of methohexital during chest tube removal in neonates. Paediatr Anaesth 2004; 14: 308-312.
8. Allegaert K, Tibboel D, Naulaers G, Tison D, De Jonge A, van Dijk M, et al: Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed. Eur J Clin Pharmacol 2003; 59: 87-90.
9. Naulaers G, Meyns B, Miserez M, Leunens V, Van Huffel S, Casaer P, et al : Use of tissue oxygenation index and fractional tissue oxygen extraction as non-invasive parameters for cerebral oxygenation. A validation study in piglets. Neonatology 2007; 92: 120-126.
10. Fairfield JE, Dritsas A, Beale RJ: Haemodynamic effects of propofol: induction with 2.5 mg kg -1 . Br J Anaesth 1991; 67: 618-620.
11. Graham MR, Thiessen DB, Mutch WA: Left ventricular systolic and diastolic function is unaltered during propofol infusion in newborn swine. Anesth Analg 1998; 86: 717-723.
12. Maneglia R, Cousin MT: A comparison between propofol and ketamine for anaesthesia in the elderly. Haemodynamic effects during induction and maintenance. Anaesthesia 1988; 43(suppl):109-111.
13. Wodey E, Chonow L, Beneux X, Azzis O, Bansard JY, Ecoffey C: Haemodynamic effects of propofol vs thiopental in infants: an echocardiographic study. Br J Anaesth 1999; 82: 516-520.
14. Hung YC, Huang CJ, Kuok CH, Chen CC, Hsu YW: The effect of hemodynamic changes induced by propofol induction on cerebral oxygenation in young and elderly patients. J Clin Anesth 2005; 17: 353-357.
15. Hertzog JH, Campbell JK, Dalton HJ, Hauser GJ: Propofol anesthesia for invasive procedures in ambulatory and hospitalized children: experience in the pediatric intensive care unit. Pediatrics 1999; 103:E30.
16. Lovell AT, Owen-Reece H, Elwell CE, Smith M, Goldstone JC: Continuous measurement of cerebral oxygenation by near infrared spectroscopy during induction of anesthesia. Anesth Analg 1999; 88: 554-558.
17. Short SM, Aun CS: Haemodynamic effects of propofol in children. Anaesthesia 1991; 46: 783-785.
18. Tsuji M, Saul JP, du PA, Eichenwald E, Sobh J, Crocker R, et al: Cerebral intravascular oxygenation correlates with mean arterial pressure in critically ill premature infants. Pediatrics 2000; 106: 625-632.
19. 2 reactivity of brain vessels in the human. Anaesthesist 1987; 36: 60-65.
20. Vandesteene A, Trempont V, Engelman E, Deloof T, Focroul M, Schoutens A, et al: Effect of propofol on cerebral blood flow and metabolism in man. Anaesthesia 1988; 43(suppl):42-43.
21. Ramani R, Todd MM, Warner DS: A doseresponse study of the influence of propofol on cerebral blood flow, metabolism and the electroencephalogram in the rabbit. J Neurosurg Anesthesiol 1992; 4: 110-119.
22. Hara M, Kai Y, Ikemoto Y: Propofol activates GABAA receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat. Anesthesiology 1993; 79: 781-788.
23. Orser BA, Bertlik M, Wang LY, Macdonald JF: Inhibition by propofol (2,6 di-isopropylphenol) of the N-methyl- D -aspartate subtype of glutamate receptor in cultured hippocampal neurones. Br J Pharmacol 1995; 116: 1761-1768.
24. Tomoda K, Shingu K, Osawa M, Murakawa M, Mori K: Comparison of CNS effects of propofol and thiopentone in cats. Br J Anaesth 1993; 71: 383-387.
25. Doyle PW, Matta BF: Burst suppression or isoelectric encephalogram for cerebral protection: evidence from metabolic suppression studies. Br J Anaesth 1999; 83: 580-584.
26. Lagerkranser M, Stange K, Sollevi A: Effects of propofol on cerebral blood flow, metabolism, and cerebral autoregulation in the anesthetized pig. J Neurosurg Anesthesiol 1997; 9: 188-193.
27. Van Hemelrijck J, Fitch W, Mattheussen M, Van Aken H, Plets C, Lauwers T: Effect of propofol on cerebral circulation and autoregulation in the baboon. Anesth Analg 1990; 71: 49-54.
28. Werner C, Hoffman WE, Kochs E, Schulteam EJ, Albrecht RF: The effects of propofol on cerebral and spinal cord blood flow in rats. Anesth Analg 1993; 76: 971-975.
29. Hertzog JH, Campbell JK, Dalton HJ, Hauser GJ: Propofol anesthesia for invasive procedures in ambulatory and hospitalized children: experience in the pediatric intensive care unit. Pediatrics 1999; 103:E30.
30. Jacqz-Aigrain E, Daoud P, Burtin P, Maherzi S, Beaufils F: Pharmacokinetics of midazolam during continuous infusion in critically ill neonates. Eur J Clin Pharmacol 1992; 42: 329-332.
31. van Alfen-van der Velden AA, Hopman JC, Klaessens JH, Feuth T, Sengers RC, Liem KD: Effects of midazolam and morphine on cerebral oxygenation and hemodynamics in ventilated premature infants. Biol Neonate 2006; 90: 197-202. (Pubitemid 44427040)