Clinical, immunological, and genetic features of autoimmune primary adrenal insufficiency: Observations from a Norwegian registry

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 12, 2009, Pages 4882-4890

  Erichsen, Martina M ^a   Løvås, Kristian ^a,b   Skinningsrud, Beate ^c,d   Wolff, Anette B ^b   Undlien, Dag E ^c,d   Svartberg, Johan ^e,f   Fougner, Kristian J ^g   Berg, Tore J ^h   Bollerslev, Jens ^d,i   Mella, Bjarne ^j   Carlson, Joyce A ^k   Erlich, Henry ^l   Husebye, Eystein S ^a,b  

^a HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF BERGEN   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

^e UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^f UNIVERSITY OF TROMSØ   (Norway)

^g TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^h AKER UNIVERSITY HOSPITAL   (Norway)

ⁱ OSLO UNIVERSITY HOSPITAL   (Norway)

^j Østfold Hospital Trust   (Norway)

^k LUND UNIVERSITY HOSPITAL   (Sweden)

^l ROCHE MOLECULAR SYSTEMS   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; AUTOANTIBODY; CORTISONE ACETATE; FLUDROCORTISONE; HLA ANTIGEN; STEROID 21 MONOOXYGENASE;

ADDISON DISEASE; ADRENAL GLAND; ADULT; AGED; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE THYROIDITIS; AUTOIMMUNITY; CLINICAL FEATURE; COHORT ANALYSIS; COMORBIDITY; DIABETES MELLITUS; FAMILIAL DISEASE; FEMALE; GENETIC SUSCEPTIBILITY; GENETICS; GENOTYPE; HLA TYPING; HUMAN; IDIOPATHIC DISEASE; IMMUNOASSAY; INCIDENCE; MAJOR CLINICAL STUDY; MALE; NORWAY; ONSET AGE; OVARY INSUFFICIENCY; PREDICTION; PREVALENCE; PRIORITY JOURNAL; QUALITY OF LIFE; REGISTER; SHORT FORM 36; THYROID DISEASE; THYROID GLAND; VITILIGO;

EID: 73249138400     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-1368     Document Type: Article

References (38)

1. Arlt W, Allolio B 2003 Adrenal insufficiency. Lancet 361:1881-1893
2. Laureti S, Vecchi L, Santeusanio F, Falorni A 1999 Is the prevalence of Addison's disease underestimated? J Clin Endocrinol Metab 84:1762
3. Willis AC, Vince FP 1997 The prevalence of Addison's disease in Coventry, UK. Postgrad Med J 73:286-288
4. Kong MF, Jeffcoate W 1994 Eighty-six cases of Addison's disease. Clin Endocrinol (Oxf) 41:757-761
5. Løvås K, Husebye ES 2002 High prevalence and increasing incidence of Addison's disease in western Norway. Clin Endocrinol (Oxf) 56:787-791
6. Nerup J 1974 Addison's disease-clinical studies. A report of 108 cases. Acta Endocrinol (Copenh) 76:127-141
7. Falorni A, Laureti S, De Bellis A, Zanchetta R, Tiberti C, Arnaldi G, Bini V, Beck-Peccoz P, Bizzarro A, Dotta F, Mantero F, Bellastella A, Betterle C, Santeusanio F 2004 Italian Addison Network Study: update of diagnostic criteria for the etiological classification of primary adrenal insufficiency. J Clin Endocrinol Metab 89:1598-1604
8. Myhre AG, Undlien DE, Løvås K, Uhlving S, Nedrebø BG, Fougner KJ, Trovik T, Sørheim JI, Husebye ES 2002 Autoimmune adrenocortical failure in Norway autoantibodies and human leukocyte antigen class II associations related to clinical features. J Clin Endocrinol Metab 87:618-623
9. Bleicken B, Hahner S, Loeffler M, Ventz M, Allolio B, Quinkler M 2008 Impaired subjective health status in chronic adrenal insufficiency: impact of different glucocorticoid replacement regimens. Eur J Endocrinol 159:811-817
10. Hahner S, Loeffler M, Fassnacht M, Weismann D, Koschker AC, Quinkler M, Decker O, Arlt W, Allolio B 2007 Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis. J Clin Endocrinol Metab 92:3912-3922
11. Gurnell EM, Hunt PJ, Curran SE, Conway CL, Pullenayegum EM, Huppert FA, Compston JE, Herbert J, Chatterjee VK 2008 Longterm DHEA replacement in primary adrenal insufficiency: a randomized, controlled trial. J Clin Endocrinol Metab 93:400-409
12. Løvås K, Loge JH, Husebye ES 2002 Subjective health status in Norwegian patients with Addison's disease. Clin Endocrinol (Oxf) 56:581-588
13. Bergthorsdottir R, Leonsson-Zachrisson M, Odén A, Johannsson G 2006 Premature mortality in patients with Addison's disease: a population-based study. J Clin Endocrinol Metab 91:4849-4853
14. Bensing S, Brandt L, Tabaroj F, Sjöberg O, Nilsson B, Ekbom A, Blomqvist P, Kämpe O 2008 Increased death risk and altered cancer incidence pattern in patients with isolated or combined autoimmune primary adrenocortical insufficiency. Clin Endocrinol (Oxf) 69:697-704
15. Erichsen MM, Løvås K, Fougner KJ, Svartberg J, Hauge ER, Bollerslev J, Berg JP, Mella B, Husebye ES 2009 Normal overall mortality rate in Addison's disease, but young patients are at risk of premature death. Eur J Endocrinol 160:233-237
16. Løvås K, Gjesdal CG, Christensen M, Wolff AB, Almås B, Svartberg J, Fougner KJ, Syversen U, Bollerslev J, Falch JA, Hunt PJ, Chatterjee VK, Husebye ES 2009 Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone. Eur J Endocrinol 160:993-1002
17. Yu L, Brewer KW, Gates S, Wu A, Wang T, Babu SR, Gottlieb PA, Freed BM, Noble J, Erlich HA, Rewers MJ, Eisenbarth GS 1999 DRB1*04 and DQ alleles: expression of 21-hydroxylase autoantibodies and risk of progression to Addison's disease. J Clin Endocrinol Metab 84:328-335
18. Winqvist O, Karlsson FA, Kämpe O 1992 21-Hydroxylase, a major autoantigen in idiopathic Addison's disease. Lancet 339:1559-1562
19. Wolff AS, Erichsen MM, Meager A, Magitta NF, Myhre AG, Bollerslev J, Fougner KJ, Lima K, Knappskog PM, Husebye ES 2007 Autoimmune polyendocrine syndrome type 1 in Norway: phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. J Clin Endocrinol Metab 92:595-603
20. McHorney CA, Ware Jr JE, Raczek AE 1993 The MOS 36-Item Short-Form Health Survey (SF-36): II. Psychometric and clinical tests of validity in measuring physical and mental health constructs. Med Care 31:247-263
21. Loge JH, Kaasa S 1998 Short form 36 (SF-36) health survey: normative data from the general Norwegian population. Scand J Soc Med 26:250-258
22. Oftedal BE, Wolff AS, Bratland E, Kämpe O, Perheentupa J, Myhre AG, Meager A, Purushothaman R, Ten S, Husebye ES 2008 Radio-immunoassay for autoantibodies against interferon ω; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clin Immunol 129:163-169
23. Erlich H, Valdes AM, Noble J, Carlson JA, Varney M, Concannon P, Mychaleckyj JC, Todd JA, Bonella P, Fear AL, Lavant E, Louey A, Moonsamy P 2008 HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. Diabetes 57:1084-1092
24. Bøe Wolff AS, Oftedal B, Johansson S, Bruland O, Løvås K, Meager A, Pedersen C, Husebye ES, Knappskog PM 2008 AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes Immun 9:130-136
25. Meager A, Visvalingam K, Peterson P, Möll K, Murumägi A, Krohn K, Eskelin P, Perheentupa J, Husebye E, Kadota Y, Willcox N 2006 Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Med 3:e289
26. Husebye ES, Perheentupa J, Rautemaa R, Kämpe O 2009 Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I. J Intern Med 265:514-529
27. Laureti S, Casucci G, Santeusanio F, Angeletti G, Aubourg P, Brunetti P 1996 X-Linked adrenoleukodystrophy is a frequent cause of idiopathic Addison's disease in young adult male patients. J Clin Endocrinol Metab 81:470-474
28. Aamodt G, Stene LC, Njølstad PR, Søvik O, Joner G 2007 Spatiotemporal trends and age-period-cohort modeling of the incidence of type 1 diabetes among children aged <15 years in Norway 1973-1982 and 1989-2003. Diabetes Care 30:884-889
29. Betterle C, Rossi A, Dalla Pria S, Artifoni A, Pedini B, Gavasso S, Caretto A 1993 Premature ovarian failure: autoimmunity and natural history. Clin Endocrinol (Oxf) 39:35-43
30. Dal Pra C, Chen S, Furmaniak J, Smith BR, Pedini B, Moscon A, Zanchetta R, Betterle C 2003 Autoantibodies to steroidogenic enzymes in patients with premature ovarian failure with and without Addison's disease. Eur J Endocrinol 148:565-570
31. Esteban NV, Loughlin T, Yergey AL, Zawadzki JK, Booth JD, Winterer JC, Loriaux DL 1991 Daily cortisol production rate inman determined by stable isotope dilution/mass spectrometry. J Clin Endocrinol Metab 72:39-45
32. Kerrigan JR, Veldhuis JD, Leyo SA, Iranmanesh A, Rogol AD 1993 Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis. J Clin Endocrinol Metab 76:1505-1510
33. Plat L, Leproult R, L'Hermite-Baleriaux M, Fery F, Mockel J, Polonsky KS, Van Cauter E 1999 Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning. J Clin Endocrinol Metab 84:3082-3092
34. Mah PM, Jenkins RC, Rostami-Hodjegan A, Newell-Price J, Doane A, Ibbotson V, Tucker GT, Ross RJ 2004 Weight-related dosing, timing and monitoring hydrocortisone replacement therapy in patients with adrenal insufficiency. Clin Endocrinol (Oxf) 61:367-375
35. Løvås K, Thorsen TE, Husebye ES 2006 Saliva cortisol measurement: simple and reliable assessment of the glucocorticoid replacement therapy in Addison's disease. J Endocrinol Invest 29:727-731
36. Arlt W, Rosenthal C, Hahner S, Allolio B 2006 Quality of glucocorticoid replacement in adrenal insufficiency: clinical assessment vs. timed serum cortisol measurements. Clin Endocrinol (Oxf) 64:384-389
37. Debono M, Ghobadi C, Rostami-Hodjegan A, Huatan H, Campbell MJ, Newell-Price J, Darzy K, Merke DP, Arlt W, Ross RJ 2009 Modified-release hydrocortisone to provide circadian cortisol profiles. J Clin Endocrinol Metab 94:1548-1554
38. Løvås K, Husebye ES 2007 Continuous subcutaneous hydrocortisone infusion in Addison's disease. Eur J Endocrinol 157:109-112