Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T 1 MRI contrast agent: Account for large longitudinal relaxivity, optimal particle diameter, and in Vivo T1 MR images

ACS Nano

Volumn 3, Issue 11, 2009, Pages 3663-3669

  Park, Ja Young ^a   Baek, Myung Ju ^a   Choi, Eun Sook ^a   Woo, Seungtae ^b   Kim, Joo Hyun ^b   Kim, Tae Jeong ^a   Jung, Jae Chang ^a   Chae, Kwon Seok ^a   Chang, Yongmin ^a,b   Lee, Gang Ho ^a  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

Author keywords

Gadolinium oxide nanoparticle; Longitudinal relaxivity; T 1 MR imaging; Ultrasmall

Indexed keywords

BRAIN TUMORS; GADOLINIUM OXIDE; HIGH CONTRAST; IN-VIVO; ION PRECURSORS; LONGITUDINAL RELAXATION; MR IMAGES; MR IMAGING; MRI CONTRAST AGENTS; OPTIMAL RANGES; PARTICLE DIAMETERS; REFLUXING; RELAXIVITY; SURFACE-TO-VOLUME RATIO; TRIPROPYLENE GLYCOL; ULTRA-SMALL;

GLYCOLS; MAGNETIC RESONANCE IMAGING; NANOPARTICLES; PARAMAGNETIC MATERIALS; PARTICLE SIZE; PROTONS;

GADOLINIUM;

CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM; GADOLINIUM OXIDE; GLUCURONIC ACID; NANOPARTICLE; PROTON; WATER;

ANIMAL; ARTICLE; BRAIN TUMOR; CHEMISTRY; HUMAN; INFRARED SPECTROSCOPY; INJECTION; MAGNETISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; RAT; SURFACE PROPERTY; THERMOGRAVIMETRY; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CONTRAST MEDIA; GADOLINIUM; GLUCURONIC ACID; HUMANS; INJECTIONS; MAGNETIC RESONANCE IMAGING; MAGNETICS; NANOPARTICLES; PARTICLE SIZE; PROTONS; RATS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SURFACE PROPERTIES; THERMOGRAVIMETRY; WATER;

EID: 73249135370     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn900761s     Document Type: Article

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