Molecular dynamics study of the encapsulation capability of a PCL-PEO based block copolymer for hydrophobic drugs with different spatial distributions of hydrogen bond donors and acceptors

Biomaterials

Volumn 31, Issue 7, 2010, Pages 1780-1786

  Patel, Sarthak K ^a   Lavasanifar, Afsaneh ^a   Choi, Phillip ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Hydrogen bond donors and acceptors; Hydrophobic drugs; Interaction parameter; Molecular dynamics simulation; Multi block copolymer

Indexed keywords

HYDROGEN BOND DONORS; HYDROPHOBIC DRUG; INTERACTION PARAMETERS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR DYNAMICS SIMULATIONS;

BLOCK COPOLYMERS; CARBOXYLIC ACIDS; COPOLYMERIZATION; DRUG INTERACTIONS; DRUG PRODUCTS; DYNAMICS; ETHYLENE; HYDROGEN; HYDROPHOBICITY; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PLASTIC PRODUCTS; POLYETHYLENE OXIDES; PYRIDINE; STRESS ANALYSIS;

HYDROGEN BONDS;

CUCURBITACIN; CUCURBITACIN B; CUCURBITACIN I; FENOFIBRATE; MACROGOL; NIMODIPINE; POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; DRUG SOLUBILITY; DRUG STRUCTURE; ENCAPSULATION; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR WEIGHT; PRIORITY JOURNAL;

CUCURBITACINS; HYDROGEN BONDING; HYDROPHOBICITY; ISOMERISM; MOLECULAR DYNAMICS SIMULATION; NIMODIPINE; PHARMACEUTICAL PREPARATIONS; POLYESTERS; PROCETOFEN; TORSION, MECHANICAL;

EID: 73249134361     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2009.11.060     Document Type: Article

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