Oligomerized TICAM-1 (TRIF) in the cytoplasm recruits nuclear BS69 to enhance NF-κB activation and type I IFN induction

European Journal of Immunology

Volumn 39, Issue 12, 2009, Pages 3469-3476

  Takaki, Hiromi ^a   Oshiumi, Hiroyuki ^a   Sasai, Miwa ^a,b   Kawanishi, Takahiro ^a   Matsumoto, Misako ^a   Seya, Tsukasa ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BS69; IFN ; NF B; TICAM 1 TRIF; TLR3

Indexed keywords

BINDING PROTEIN; DOUBLE STRANDED RNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERFERON REGULATORY FACTOR 3; LATENT MEMBRANE PROTEIN 1; PROTEIN BS69; RNA; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; ENZYME ACTIVATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; OLIGOMERIZATION; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REPORTER GENE; RNA PURIFICATION; WESTERN BLOTTING;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; BLOTTING, WESTERN; CARRIER PROTEINS; CELL LINE; CYTOPLASM; HELA CELLS; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MICROSCOPY, CONFOCAL; NF-KAPPA B; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 73249116346     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939878     Document Type: Article

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