Adenovirus-driven overexpression of proteinases in organ-cultured normal human corneas leads to diabetic-like changes

Brain Research Bulletin

Volumn 81, Issue 2-3, 2010, Pages 262-272

  Saghizadeh, Mehrnoosh ^a   Kramerov, Andrei A ^a   Yaghoobzadeh, Yousha ^a   Hu, Jinwei ^a   Ljubimova, Julia Y ^a   Black, Keith L ^a   Castro, Maria G ^a,b   Ljubimov, Alexander V ^a,b  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Akt; Cathepsin F; Diabetic cornea; MMP 10; Organ culture; Sildenafil

Indexed keywords

ADENOVIRUS VECTOR; CATHEPSIN F; ENTACTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; LAMININ; LAMININ GAMMA2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NIDOGEN 1; NIDOGEN 2; PROTEIN KINASE B; SILDENAFIL; STROMELYSIN 2; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 3;

ADULT; AGED; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORNEA; DIABETIC KERATOPATHY; DIABETIC PATIENT; DISEASE MARKER; EMBRYO; FEMALE; GENE OVEREXPRESSION; GENE SILENCING; GENETIC CODE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATOPATHY; MALE; NEUROPATHY; NONHUMAN; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; VIRUS RECOMBINANT; WESTERN BLOTTING; WOUND HEALING IMPAIRMENT;

ADENOVIRIDAE; ADENOVIRIDAE INFECTIONS; ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CATHEPSIN F; CELLS, CULTURED; CORNEA; CRICETINAE; CRICETULUS; DIABETES MELLITUS; EYE PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; PEPTIDE HYDROLASES; PHOSPHORYLATION; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSDUCTION, GENETIC; WOUND HEALING;

EID: 73149118241     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2009.10.007     Document Type: Article

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