BCA2/rabring7 promotes tetherin-dependent HIV-1 restriction

PLoS Pathogens

Volumn 5, Issue 12, 2009, Pages

  Miyakawa, Kei ^a,b   Ryo, Akihide ^a   Murakami, Tsutomu ^a   Ohba, Kenji ^a   Yamaoka, Shoji ^b   Fukuda, Mitsunori ^c   Guatelli, John ^d   Yamamoto, Naoki ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD63 ANTIGEN; MEMBRANE PROTEIN; PROTEIN BCA2; PROTEIN TETHERIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BST2 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; RNF115 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL MEMBRANE; CELL SURFACE; GENETIC TRANSFECTION; HELA CELL; HOST CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INTRACELLULAR SPACE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN INTERACTION; RNA INTERFERENCE; VIRION; VIRUS INHIBITION; VIRUS PARTICLE; VIRUS REPLICATION; CELL LINE; ENDOCYTOSIS; IMMUNOLOGY; INNATE IMMUNITY; LYSOSOME; METABOLISM; PHYSIOLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTIGENS, CD; CELL LINE; ENDOCYTOSIS; HIV-1; HUMANS; IMMUNITY, INNATE; LYSOSOMES; MEMBRANE GLYCOPROTEINS; UBIQUITIN-PROTEIN LIGASES; VIRION; VIRUS REPLICATION;

EID: 73149102228     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000700     Document Type: Article

References (38)

1. Goff SP (2007) Host factors exploited by retroviruses. Nat Rev Microbiol 5: 253-263.
2. Huthoff H, Towers GJ (2008) Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha. Trends Microbiol 16: 612-619.
3. Freed EO (2004) HIV-1 and the host cell: an intimate association. Trends Microbiol 12: 170-177.
4. Malim MH, Emerman M (2008) HIV-1 accessory proteins-ensuring viral survival in a hostile environment. Cell Host Microbe 3: 388-398.
5. Neil SJ, Sandrin V, Sundquist WI, Bieniasz PD (2007) An interferon-alphainduced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein. Cell Host Microbe 2: 193-203.
6. Neil SJ, Zang T, Bieniasz PD (2008) Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu. Nature 451: 425-430.
7. Van Damme N, Goff D, Katsura C, Jorgenson RL, Mitchell R, et al. (2008) The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein. Cell Host Microbe 3: 245-252.
8. Jouvenet N, Neil SJ, Zhadina M, Zang T, Kratovac Z, et al. (2009) Broadspectrum inhibition of retroviral and filoviral particle release by tetherin. J Virol 83: 1837-1844.
9. Sakuma T, Noda T, Urata S, Kawaoka Y, Yasuda J (2009) Inhibition of Lassa and Marburg virus production by tetherin. J Virol 83: 2382-2385.
10. Kaletsky RL, Francica JR, Agrawal-Gamse C, Bates P (2009) Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein. Proc Natl Acad Sci U S A 106: 2886-2891.
11. Strebel K, Klimkait T, Martin MA (1988) A novel gene of HIV-1, vpu, and its 16-kilodalton product. Science 241: 1221-1223.
12. Cohen EA, Terwilliger EF, Sodroski JG, Haseltine WA (1988) Identification of a protein encoded by the vpu gene of HIV-1. Nature 334: 532-534.
13. Huet T, Cheynier R, Meyerhans A, Roelants G, Wain-Hobson S (1990) Genetic organization of a chimpanzee lentivirus related to HIV-1. Nature 345: 356-359.
14. Klimkait T, Strebel K, Hoggan MD, Martin MA, Orenstein JM (1990) The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release. J Virol 64: 621-629.
15. Neil SJ, Eastman SW, Jouvenet N, Bieniasz PD (2006) HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane. PLoS Pathog 2: e39. doi: 10.1371/journal.ppat.0020039.
16. Willey RL, Maldarelli F, Martin MA, Strebel K (1992) Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. J Virol 66: 7193-7200.
17. Willey RL, Maldarelli F, Martin MA, Strebel K (1992) Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes. J Virol 66: 226-234.
18. Chen MY, Maldarelli F, Karczewski MK, Willey RL, Strebel K (1993) Human immunodeficiency virus type 1 Vpu protein induces degradation of CD4 in vitro: the cytoplasmic domain of CD4 contributes to Vpu sensitivity. J Virol 67: 3877-3884.
19. Miyagi E, Andrew AJ, Kao S, Strebel K (2009) Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion. Proc Natl Acad Sci U S A 106: 2868-2873.
20. Gottlinger HG, Dorfman T, Cohen EA, Haseltine WA (1993) Vpu protein of human immunodeficiency virus type 1 enhances the release of capsids produced by gag gene constructs of widely divergent retroviruses. Proc Natl Acad Sci U S A 90: 7381-7385.
21. Strebel K, Klimkait T, Maldarelli F, Martin MA (1989) Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein. J Virol 63: 3784-3791.
22. Terwilliger EF, Cohen EA, Lu YC, Sodroski JG, Haseltine WA (1989) Functional role of human immunodeficiency virus type 1 vpu. Proc Natl Acad Sci U S A 86: 5163-5167.
23. Harila K, Prior I, Sjoberg M, Salminen A, Hinkula J, et al. (2006) Vpu and Tsg101 regulate intracellular targeting of the human immunodeficiency virus type 1 core protein precursor Pr55gag. J Virol 80: 3765-3772.
24. Harila K, Salminen A, Prior I, Hinkula J, Suomalainen M (2007) The Vpuregulated endocytosis of HIV-1 Gag is clathrin-independent. Virology 369: 299-308.
25. Van Damme N, Guatelli J (2008) HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes. Cell Microbiol 10: 1040-1057.
26. Mizuno K, Kitamura A, Sasaki T (2003) Rabring7, a novel Rab7 target protein with a RING finger motif. Mol Biol Cell 14: 3741-3752.
27. Adachi A, Gendelman HE, Koenig S, Folks T, Willey R, et al. (1986) Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 59: 284-291.
28. Sakane A, Hatakeyama S, Sasaki T (2007) Involvement of Rabring7 in EGF receptor degradation as an E3 ligase. Biochem Biophys Res Commun 357: 1058-1064.
29. Amemiya Y, Azmi P, Seth A (2008) Autoubiquitination of BCA2 RING E3 ligase regulates its own stability and affects cell migration. Mol Cancer Res 6: 1385-1396.
30. Luzio JP, Rous BA, Bright NA, Pryor PR, Mullock BM, et al. (2000) Lysosomeendosome fusion and lysosome biogenesis. J Cell Sci 113: 1515-1524.
31. Piper RC, Luzio JP (2001) Late endosomes: sorting and partitioning in multivesicular bodies. Traffic 2: 612-621.
32. Burger AM, Gao Y, Amemiya Y, Kahn HJ, Kitching R, et al. (2005) A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer. Cancer Res 65: 10401-10412.
33. Burger A, Amemiya Y, Kitching R, Seth AK (2006) Novel RING E3 ubiquitin ligases in breast cancer. Neoplasia 8: 689-695.
34. Nguyen KL, llano M, Akari H, Miyagi E, Poeschla EM, et al. (2004) Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. Virology 319: 163-175.
35. Ohba K, Ryo A, Dewan MZ, Nishi M, Naito T, et al. (2009) Follicular dendritic cells activate HIV-1 replication in monocytes/macrophages through a juxtacrine mechanism mediated by P-selectin glycoprotein ligand 1. J Immunol 183: 524-532.
36. Maldarelli F, Chen MY, Willey RL, Strebel K (1993) Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein. J Virol 67: 5056-5061.
37. Ozaki S, Kosaka M, Wakahara Y, Ozaki Y, Tsuchiya M, et al. (1999) Humanized anti-HM1.24 antibody mediates myeloma cell cytotoxicity that is enhanced by cytokine stimulation of effector cells. Blood 93: 3922-3930.
38. Ryo A, Tsurutani N, Ohba K, Kimura R, Komano J, et al. (2008) SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag. Proc Natl Acad Sci U S A 105: 294-299.