Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma

Archives of Surgery

Volumn 144, Issue 12, 2009, Pages 1144-1148

  Duan, Zhao Xia ^a   Gu, Wei ^a   Zhang, Lian Yang ^a   Du, Ding Yuan ^b   Hu, Ping ^b   Huang, Jian ^a   Liu, Qing ^a   Wang, Zheng Guo ^a   Hao, Jiang ^c   Jiang, Jian Xin ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b CHONGQING EMERGENCY MEDICAL CENTER   (China)

^c Chengdu Military Command   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CLINICAL ASSESSMENT; DNA POLYMORPHISM; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INJURY; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; MULTIPLE ORGAN FAILURE; POSTTRAUMATIC COMPLICATION; PRIORITY JOURNAL; SEPSIS; STIMULATION;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; COHORT STUDIES; FEMALE; GENOTYPE; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; MULTIPLE ORGAN FAILURE; POLYMORPHISM, GENETIC; SEPSIS; TOLL-LIKE RECEPTOR 4; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 73149089449     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.2009.211     Document Type: Article

References (42)

1. Wang Z, Jiang JX. An overview of research advances in road traffic trauma in China. Traffic Inj Prev. 2003;4(1):9-16.
2. Wang ZG. Advances in basically scientific research on trauma. Chin J Traumatol. 2005;21:6-10.
3. Ciesla DJ, Moore EE, Johnson JL, Burch JM, Cothren CC, Sauaia A. A 12-year prospective study of postinjury multiple organ failure. Arch Surg. 2005;140(5):432-440.
4. Lango H, Weedon MN. What will whole genome searches for susceptibility genes for common complex disease offer to clinical practice? J Intern Med. 2008;263(1):16-27.
5. Shastry BS. SNPs in disease gene mapping, medicinal drug development and evolution. J Hum Genet. 2007;52(11):871-880.
6. Arcaroli J, Fessler MB, Abraham E. Genetic polymorphisms and sepsis. Shock. 2005;24(4):300-312.
7. Jiang JX, Zhu PF, Wang ZG. Receptor-signal transduction: mechanisms of endotoxin actions. Crit Care Shock. 2000;3:35-48.
8. Mollen KP, Anand RJ, Tsung A, Prince JM, Levy RM, Billiar TR. Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage. Shock. 2006;26(5):430-437.
9. Mollen KP, Levy RM, Prince JM, et al. Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrowderived cells and parenchymal cells. J Leukoc Biol. 2008;83(1):80-88.
10. McDaniel DO, Hamilton J, Brock M, et al. Molecular analysis of inflammatory markers in trauma patients at risk of postinjury complications. J Trauma. 2007;63(1):147-158.
11. Qureshi ST, Lariviere L, Leveque G, et al. Endotoxin-tolerant mice have mutations in toll-like receptor 4 (Tlr4). J Exp Med. 1999;189(4):615-625.
12. Hoshino K, Takeuchi O, Kawai T, et al. Cutting edge: toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol. 1999;162(7):3749-3752.
13. Ferwerda B, McCall MB, Alonso S, et al. TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans. Proc Natl Acad Sci U S A. 2007;104(42):16645-16650.
14. Achyut BR, Ghoshal UC, Moorchung N, Mittal B. Association of toll-like receptor-4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions. Hum Immunol. 2007;68(11):901-907.
15. Tulic MK, Hurrelbrink RJ, Prêle CM, et al. TLR4 polymorphisms mediate impaired responses to respiratory syncytial virus and lipopolysaccharide. J Immunol. 2007;179(1):132-140.
16. Cervera C, Lozano F, Saval N, et al. The influence of innate immunity gene receptors polymorphisms in renal transplant infections. Transplantation. 2007;83(11):1493-1500.
17. Candore G, Aquino A, Balistreri CR, et al. Inflammation, longevity, and cardiovascular diseases: role of polymorphisms of TLR4. Ann N Y Acad Sci. 2006;1067:282-287.
18. Schröder NW, Schumann RR. Single nucleotide polymorphisms of Toll-like receptors and susceptibility to infectious disease. Lancet Infect Dis. 2005;5(3):156-164.
19. Barber RC, Aragaki CC, Rivera-Chavez FA, Purdue GF, Hunt JL, Horton JW. TLR4 and TNF-alpha polymorphisms are associated with an increased risk for severe sepsis following burn injury. J Med Genet. 2004;41(11):808-813.
20. Edfeldt K, Bennet AM, Eriksson P, et al. Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction. Eur Heart J. 2004;25(16):1447-1453.
21. Agnese DM, Calvano JE, Hahm SJ, et al. Human toll-like receptor 4 mutations but not CD14 polymorphisms are associated with an increased risk of gramnegative infections. J Infect Dis. 2002;186(10):1522-1525.
22. Arbour NC, Lorenz E, Schutte BC, et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet. 2000;25(2):187-191.
23. Urcelay E, Blanco-Kelly F, de Las Heras V, de la Concha EG, Arroyo R, Mart?́nez A. TLR4 haplotypes in multiple sclerosis: a case-control study in the Spanish population. J Neuroimmunol. 2007;192(1-2):215-218.
24. Hong J, Leung E, Fraser AG, Merriman TR, Vishnu P, Krissansen GW. TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort. J Gastroenterol Hepatol. 2007;22(11):1760-1766.
25. Kumpf O, Hamann L, Schlag PM, Schumann RR. Pre- and postoperative cytokine release after in vitro whole blood lipopolysaccharide stimulation and frequent toll-like receptor 4 polymorphisms. Shock. 2006;25(2):123-128.
26. Feng K, Zhou GQ, Zhai Y, et al. Study on single nucleotide polymorphism of TLR4 in Chinese population [in Chinese]. Chin J Med Genet. 2005;22:99-101.
27. Duan ZX, Zhu PF, Dong H, et al. Functional significance of the TLR4 /11367 polymorphism identified in Chinese Han population. Shock. 2007;28(2):160-164.
28. Association for the Advancement of Automotive Medicine. Abbreviated Injury Scale (AIS) 1990: Update 98. Barrington, IL: Association for the Advancement of Automotive Medicine; 1998.
29. Jiang Z, Shi J, Yang S, et al. Single-tube bi-directional allele specific amplification is a new way for single nucleotide polymorphism genotyping. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001;18:306-309.
30. Wen AQ, Wang J, Feng K, Zhu PF, Wang ZG, Jiang JX. Effects of haplotypes in the interleukin 1 beta promoter on lipopolysacchride-induced interleukin 1 beta expression. Shock. 2006;26(1):25-30.
31. Marshall JC, Cook DJ, Christou NV, Bernard GR, Sprung CL, Sibbald WJ. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995;23(10):1638-1652.
32. Guo QS, Xia B, Jiang Y, et al. Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients. Postgrad Med J. 2005;81(958):526-529.
33. Nakada TA, Hirasawa H, Oda S, et al. Influence of toll-like receptor 4, CD14, tumor necrosis factor, and interleukine-10 gene polymorphisms on clinical outcome in Japanese critically ill patients. J Surg Res. 2005;129(2):322-328.
34. Okayama N, Fujimura K, Suehiro Y, et al. Simple genotype analysis of the Asp299Gly polymorphism of the Toll-like receptor-4 gene that is associated with lipopolysaccharide hyporesponsiveness. J Clin Lab Anal. 2002;16(1):56-58.
35. Lausevic Z, Lausevic M, Trbojevic-Stankovic J, Krstic S, Stojimirovic B. Predicting multiple organ failure in patients with severe trauma. Can J Surg. 2008;51(2):97-102.
36. Lazarus HM, Fox J, Lloyd JF, et al. A six-year descriptive study of hospitalassociated infection in trauma patients: demographics, injury features, and infection patterns. Surg Infect (Larchmt). 2007;8(4):463-473.
37. Majetschak M, Krehmeier U, Ostroverkh L, Blömeke B, Schäfer M. Alterations in leukocyte function following surgical trauma: differentiation of distinct reaction types and association with tumor necrosis factor gene polymorphisms. Clin Diagn Lab Immunol. 2005;12(2):296-303.
38. Gu W, Du DY, Huang J, et al. Identification of Interleukin-6 promoter polymorphisms in Chinese Han population and their functional significance. Crit Care Med. 2008;36(5):1437-1443.
39. Schröder O, Laun RA, Held B, Ekkernkamp A, Schulte KM. Association of interleukin-10 promoter polymorphism with the incidence of multiple organ dysfunction following major trauma: results of a prospective pilot study. Shock. 2004;21(4):306-310.
40. Gu W, Shan YA, Zhou J, et al. Functional significance of gene polymorphisms in the promoter of myeloid differentiation-2. Ann Surg. 2007;246(1):151-158.
41. Stassen NA, Leslie-Norfleet LA, Robertson AM, Eichenberger MR, Polk HC Jr. Interferon-gamma gene polymorphisms and the development of sepsis in patients with trauma. Surgery. 2002;132(2):289-292.
42. Stassen NA, Breit CM, Norfleet LA, Polk HC Jr. IL-18 promoter polymorphisms correlate with the development of post-injury sepsis. Surgery. 2003;134(2):351-356.