Structure of the lethal phage pinhole

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 45, 2009, Pages 18966-18971

  Pang, Ting ^a   Savva, Christos G ^a,b   Fleming, Karen G ^c   Struck, Douglas K ^a   Young, Ry ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b Texas AandM University   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Glycine zipper; Holin; Lysis; SAR domain; Thiol modification

Indexed keywords

BACTERIAL PROTEIN; CYSTEINE; PROTEIN PINHOLIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIOPHAGE; CELL ORGANELLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; CROSS LINKING; CYTOPLASM; DENATURATION; DIMERIZATION; IMMUNOBLOTTING; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY;

AMINO ACID SEQUENCE; BACTERIOLYSIS; BACTERIOPHAGES; CHROMATOGRAPHY, GEL; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; VIRAL PROTEINS;

EID: 73149088830     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0907941106     Document Type: Article

References (37)

1. Young R, Wang IN (2006) Phage Lysis. The Bacteriophages, ed Calendar R (Oxford Univ Press, Oxford), 2nd Ed, pp 104-126.
2. Berry J, Summer EJ, Struck DK, Young R (2008) The final step in the phage infection cycle: The Rz and Rz1 lysis proteins link the inner and outer membranes. Mol Microbiol 70:341-351.
3. Young R (2002) Bacteriophage holins: Deadly diversity. J Mol Microbiol Biotechnol 4:21-36.
4. Bläsi U, Young R (1996) Two beginnings for a single purpose: The dual-start holins in the regulation of phage lysis. Mol Microbiol 21:675-682.
5. Wang IN, Deaton J, Young R (2003) Sizing the holin lesion with an endolysin-beta-galactosidase fusion. J Bacteriol 185:779-787.
6. Xu M, Struck DK, Deaton J, Wang IN, Young R (2004) The signal arrest-release (SAR) sequence mediates export and control of the phage P1 endolysin. Proc Natl Acad Sci USA 101:6415-6420.
7. Park T, Struck DK, Deaton JF, Young R (2006) Topological dynamics of holins in programmed bacterial lysis. Proc Natl Acad Sci USA 103:19713-19718.
8. Park T, Struck DK, Dankenbring CA, Young R (2007) The pinholin of lambdoid phage 21: Control of lysis by membrane depolarization. J Bacteriol 189:9135-9139.
9. Xu M, et al. (2005) Disulfide isomerization after membrane release of its SAR domain activates P1 lysozyme. Science 307:113-117.
10. Wagner PL, et al. (2002) Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli. Mol Microbiol 44:957-970.
11. Wagner PL, Waldor MK (2002) Bacteriophage control of bacterial virulence. Infect Immun 70:3985-3993.
12. Barenboim M, Chang CY, dib Hajj F, Young R (1999) Characterization of the dual start motif of a class II holin gene. Mol Microbiol 32:715-727.
13. Rosevear P, VanAken T, Baxter J, Ferguson-Miller S (1980) Alkyl glycoside detergents: A simpler synthesis and their effects on kinetic and physical properties of cytochrome c oxidase. Biochemistry 19:4108-4115.
14. VanAken T, Foxall-VanAken S, Castleman S, Ferguson-Miller S (1986) Alkyl glycoside detergents: Synthesis and applications to the study of membrane proteins. Methods Enzymol 125:27-35.
15. Aoudia M, Zana R (1998) Aggregation behavior of sugar surfactants in aqueous solutions: Effects of temperature and the addition of nonionic polymers. J Colloid Interface Sci 206:158-167.
16. Strop P, Brunger AT (2005) Refractive index-based determination of detergent concentration and its application to the study of membrane proteins. Protein Sci 14:2207-2211.
17. Akabas MH, Stauffer DA, Xu M, Karlin A (1992) Acetylcholine receptor channel structure probed in cysteine-substitution mutants. Science 258:307-310.
18. Kaplan RS, et al. (2000) The yeast mitochondrial citrate transport protein. Probing the secondary structure of transmembrane domain iv and identification of residues that likely comprise a portion of the citrate translocation pathway. J Biol Chem 275:12009-12016.
19. Pattabiraman N, Ward KB, Fleming PJ (1995) Occluded molecular surface: Analysis of protein packing. J Mol Recognit 8:334-344.
20. Fleming KG, Engelman DM (2001) Computation and mutagenesis suggest a structure for the synaptobrevin transmembrane dimer. Proteins 45:313-317.
21. Schein SJ, Kagan BL, Finkelstein A (1978) Colicin K acts by forming voltage-dependent channels in phospholipid bilayer membranes. Nature 276:159-163.
22. Davidson VL, Brunden KR, Cramer WA, Cohen FS (1984) Studies on the mechanism of action of channel-forming colicins using artificial membranes. J Membrane Biol 79:105-118.
23. Kim S, et al. (2005) Transmembrane glycine zippers: Physiological and pathological roles in membrane proteins. Proc Natl Acad Sci USA 102:14278-14283.
24. Russ WP, Engelman DM (2000) The GxxxG motif: A framework for transmembrane helix-helix association. J Mol Biol 296:911-919.
25. Plotkowski ML, et al. (2007) Transmembrane domain of myelin protein zero can form dimers: Possible implications for myelin construction. Biochemistry 46:12164-12173.
26. Bonovich MT, Young R (1991) Dual start motif in two lambdoid S genes unrelated to lambda S. J Bacteriol 173:2897-2905.
27. Gründling A, Manson MD, Young R (2001) Holins kill without warning. Proc Natl Acad Sci USA 98:9348-9352.
28. Miroux B, Walker JE (1996) Over-production of proteins in Escherichia coli: Mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels. J Mol Biol 260:289-298.
29. Savva CG, et al. (2008) The holin of bacteriophage lambda forms rings with large diameter. Mol Microbiol 69:784-793.
30. Valentine RC, Shapiro BM, Stadtman ER (1968) Regulation of glutamine synthetase. XII. Electron microscopy of the enzyme from Escherichia coli. Biochemistry 7:2143-2152.
31. Ludtke SJ, Baldwin PR, Chiu W (1999) EMAN: Semiautomated software for high-resolution single-particle reconstructions. J Struct Biol 128:82-97.
32. Lu J, Deutsch C (2001) Pegylation: A method for assessing topological accessibilities in Kv1.3. Biochemistry 40:13288-13301.
33. Tran TA, Struck DK, Young R (2007) The T4 RI antiholin has an N-terminal signal anchor release domain that targets it for degradation by DegP. J Bacteriol 189:7618-7625.
34. Adams PD, Arkin IT, Engelman DM, Brunger AT (1995) Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban. Nat Struct Biol 2:154-162.
35. Adams PD, Engelman DM, Brunger AT (1996) Improved prediction for the structure of the dimeric transmembrane domain of glycophorin A obtained through global searching. Proteins 26:257-261.
36. Jorgensen WL, Tirado-Rives J (1988) The OPLS [optimized potentials for liquid simulations] potential functions for proteins, energy minimizations for crystals of cyclic peptides and crambin. J Am Chem Soc 110:1657-1666.
37. McDonald IK, Thornton JM (1994) Satisfying hydrogen bonding potential in proteins. J Mol Biol 238:777-793.