Early cardiac iron overload in children with transfusion-dependent anemias

Haematologica

Volumn 94, Issue 12, 2009, Pages 1776-1777

  Fernandes, Juliano Lara ^a   Fabron Jr , Antonio ^b   Verissimo, Monica ^c  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FACULDADE DE MEDICINA DE MARÍLIA   (Brazil)

^c CENTRO INFANTIL BOLDRINI   (Brazil)

Author keywords

Iron overload; Transfusional requirements; Young children

Indexed keywords

CHELATING AGENT; DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; FERRITIN; IRON;

ADOLESCENT; ADULT; BLOOD TRANSFUSION; CARDIAC IRON OVERLOAD; CHELATION THERAPY; CHILD; CLINICAL ARTICLE; DISEASE COURSE; DYSPNEA; ELECTROCARDIOGRAM; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; HEART FAILURE; HEART VENTRICLE; HUMAN; HYPOTHESIS; IRON OVERLOAD; LETTER; MALE; MYELODYSPLASTIC SYNDROME; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT COMPLIANCE; PRESCRIPTION; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SCREENING; SICKLE CELL ANEMIA; SIDEROBLASTIC ANEMIA; SIDEROSIS; THALASSEMIA MAJOR;

ADOLESCENT; ANEMIA; BETA-THALASSEMIA; BLOOD TRANSFUSION; CHELATION THERAPY; CHILD; DEFEROXAMINE; FEMALE; HUMANS; IRON; IRON CHELATING AGENTS; IRON OVERLOAD; MAGNETIC RESONANCE IMAGING; MALE; MYOCARDIUM; PYRIDONES; RISK FACTORS;

EID: 73149083256     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.013193     Document Type: Letter

References (8)

1. Modell B, Khan M, Darlison M, Westwood MA, Ingram D, Pennell DJ. Improved survival of thalassaemia major in the UK and relation to T2* cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2008;10:42.
2. Aessopos A, Berdoukas V, Tsironi M. The heart in transfusion dependent homozygous thalassaemia today - prediction, prevention and management. Eur J Haematol 2008;80:93-106.
3. Wood JC, Origa R, Agus A, Matta G, Coates TD, Galanello R. Onset of cardiac iron loading in pediatric patients with thalassemia major. Haematologica 2008;93:917-20.
4. Wood JC, Tyszka JM, Carson S, Nelson MD, Coates TD. Myocardial iron loading in transfusion-dependent thalassemia and sickle cell disease. Blood 2004;103:1934-6.
5. Angelucci E, Barosi G, Camaschella C, Cappellini MD, Cazzola M, Galanello R, et al. Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders. Haematologica 2008;93:741-52.
6. Anderson LJ, Holden S, Davis B, Prescott E, Charrier CC, Bunce NH, et al. Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload. Eur Heart J 2001;22:2171-9.
7. Di Tucci AA, Matta G, Deplano S, Gabbas A, Depau C, Derudas D, et al. Myocardial iron overload assessment by T2* magnetic resonance imaging in adult transfusion dependent patients with acquired anemias. Haematologica 2008;93:1385-8.
8. Robbers-Visser D, Boersma E, Helbing WA. Normal biventricular function, volumes, and mass in children aged 8 to 17 years. J Magn Reson Imaging 2009;29:552-9.