Sodium valproate at the therapeutic concentration inhibits the induction but not the maintenance phase of long-term potentiation in rat hippocampal CA1 area

Biochemical and Biophysical Research Communications

Volumn 391, Issue 1, 2010, Pages 582-586

  Wu, Peng ^a   Jiang, Li ^a   Chen, HengSheng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Cognitive impairments; Hippocampal slices; Long term potentiation; Valproate

Indexed keywords

VALPROIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG INHIBITION; DRUG MECHANISM; EXCITATORY POSTSYNAPTIC POTENTIAL; FACILITATION; HIGH FREQUENCY OSCILLATION; HIPPOCAMPUS; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PAIRED PULSE FACILITATION; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT;

ANIMALS; ANTICONVULSANTS; CA1 REGION, HIPPOCAMPAL; EXCITATORY POSTSYNAPTIC POTENTIALS; LONG-TERM POTENTIATION; MALE; RATS; RATS, WISTAR; VALPROIC ACID;

RATTUS;

EID: 72949122799     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2009.11.102     Document Type: Article

References (34)

1. Drane D.L., and Meador K.J. Cognitive and behavioral effects of antiepileptic drugs. Epilepsy Behav. 3 (2002) 49-53
2. Meador K.J., Baker G., Cohen M.J., Gaily E., and Westerveld M. Cognitive/behavioral teratogenetic effects of antiepileptic drugs. Epilepsy Behav. 11 (2007) 292-302
3. Post R.M., Ketter T.A., Denicoff K., Pazzaglia P.J., Leverich G.S., Marangell L.B., Callahan A.M., George M.S., and Frye M.A. The place of anticonvulsant therapy in bipolar illness. Psychopharmacology (Berl.) 128 (1996) 115-129
4. Loscher W. Valproate: a reappraisal of its pharmacodynamic properties and mechanisms of action. Prog. Neurobiol. 58 (1999) 31-59
5. Aldenkamp A., Vigevano F., Arzimanoglou A., and Covanis A. Role of valproate across the ages. Treatment of epilepsy in children. Acta Neurol. Scand. Suppl. 184 (2006) 1-13
6. Meador K.J., Loring D.W., Huh K., Gallagher B.B., and King D.W. Comparative cognitive effects of anticonvulsants. Neurology 40 (1990) 391-394
7. Meador K.J., Loring D.W., Moore E.E., Thompson W.O., Nichols M.E., Oberzan R.E., Durkin M.W., Gallagher B.B., and King D.W. Comparative cognitive effects of phenobarbital, phenytoin, and valproate in healthy adults. Neurology 45 (1995) 1494-1499
8. Smith D.B., Mattson R.H., Cramer J.A., Collins J.F., Novelly R.A., and Craft B. Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone. Epilepsia 28 Suppl. 3 (1987) S50-S58
9. Wu Y., and Wang L. The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats. Brain Dev. 24 (2002) 82-87
10. Balakrishnan S., and Pandhi P. Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats. Methods Find. Exp. Clin. Pharmacol. 19 (1997) 693-697
11. VanDongen A.M., VanErp M.G., and Voskuyl R.A. Valproate reduces excitability by blockage of sodium and potassium conductance. Epilepsia 27 (1986) 177-182
12. Loscher W. Valproate enhances GABA turnover in the substantia nigra. Brain Res. 501 (1989) 198-203
13. Bliss T.V., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
14. Lynch M.A. Long-term potentiation and memory. Physiol. Rev. 84 (2004) 87-136
15. Zhang M.M., Xiao C., Yu K., and Ruan D.Y. Effects of sodium valproate on synaptic plasticity in the CA1 region of rat hippocampus. Food Chem. Toxicol. 41 (2003) 1617-1623
16. Zhang M.M., Yu K., Xiao C., and Ruan D.Y. The influence of developmental periods of sodium valproate exposure on synaptic plasticity in the CA1 region of rat hippocampus. Neurosci. Lett. 351 (2003) 165-168
17. Martin E.D., and Pozo M.A. Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons. Neuropharmacology 46 (2004) 555-561
18. Lee G.Y., Brown L.M., and Teyler T.J. The effects of anticonvulsant drugs on long-term potentiation (LTP) in the rat hippocampus. Brain Res. Bull. 39 (1996) 39-42
19. Loscher W. The pharmacokinetics of antiepileptic drugs in rats: consequences for maintaining effective drug levels during prolonged drug administration in rat models of epilepsy. Epilepsia 48 (2007) 1245-1258
20. Isaac J.T., Luthi A., Palmer M.J., Anderson W.W., Benke T.A., and Collingridge G.L. An investigation of the expression mechanism of LTP of AMPA receptor-mediated synaptic transmission at hippocampal CA1 synapses using failures analysis and dendritic recordings. Neuropharmacology 37 (1998) 1399-1410
21. Commins S., Gigg J., Anderson M., and O'Mara S.M. Interaction between paired-pulse facilitation and long-term potentiation in the projection from hippocampal area CA1 to the subiculum. Neuroreport 9 (1998) 4109-4113
22. Malenka R.C., and Nicoll R.A. Long-term potentiation - a decade of progress?. Science 285 (1999) 1870-1874
23. Griffith W.H., and Taylor L. Sodium valproate decreases synaptic potentiation and epileptiform activity in hippocampus. Brain Res. 474 (1988) 155-164
24. Alkadhi K.A., and Banks F.W. Pre- and postsynaptic actions of valproic acid at the frog neuromuscular junction. Brain Res. 306 (1984) 388-390
25. Pastalkova E., Serrano P., Pinkhasova D., Wallace E., Fenton A.A., and Sacktor T.C. Storage of spatial information by the maintenance mechanism of LTP. Science 313 (2006) 1141-1144
26. Kelly K.M., Gross R.A., and Macdonald R.L. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neurosci. Lett. 116 (1990) 233-238
27. Armand V., Louvel J., Pumain R., Ronco G., and Villa P. Effects of various valproic acid derivatives on low-calcium spontaneous epileptiform activity in hippocampal slices. Epilepsy Res. 22 (1995) 185-192
28. Kauer J.A., Malenka R.C., and Nicoll R.A. NMDA application potentiates synaptic transmission in the hippocampus. Nature 334 (1988) 250-252
29. Bliss T.V., and Gardner-Medwin A.R. Long-lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232 (1973) 357-374
30. Bliss T.V., and Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232 (1973) 331-356
31. Lisman J., Malenka R.C., Nicoll R.A., and Malinow R. Learning mechanisms: the case for CaM-KII. Science 276 (1997) 2001-2002
32. Frey U., and Morris R.G. Synaptic tagging and long-term potentiation. Nature 385 (1997) 533-536
33. Nguyen P.V., Abel T., and Kandel E.R. Requirement of a critical period of transcription for induction of a late phase of LTP. Science 265 (1994) 1104-1107
34. Fazeli M.S., Corbet J., Dunn M.J., Dolphin A.C., and Bliss T.V. Changes in protein synthesis accompanying long-term potentiation in the dentate gyrus in vivo. J. Neurosci. 13 (1993) 1346-1353