Dynamical effects of epigenetic silencing of 14-3-3σ expression

Molecular BioSystems

Volumn 6, Issue 1, 2009, Pages 264-273

  Vera, Julio ^a   Schultz, Julia ^a   Ibrahim, Saleh ^b   Raatz, Yvonne ^b   Wolkenhauer, Olaf ^a   Kunz, Manfred ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MDM2 PROTEIN, HUMAN; PROTEIN 14 3 3; PROTEIN MDM2; PROTEIN P53;

ARTICLE; GENE SILENCING; GENETIC EPIGENESIS; GENETICS; HUMAN; IMMUNOBLOTTING; METABOLISM; POLYMERASE CHAIN REACTION; THEORETICAL MODEL; TUMOR CELL LINE;

14-3-3 PROTEINS; CELL LINE, TUMOR; EPIGENESIS, GENETIC; GENE SILENCING; HUMANS; IMMUNOBLOTTING; MODELS, THEORETICAL; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 72949106670     PISSN: 1742206X     EISSN: 17422051     Source Type: Journal    
DOI: 10.1039/b907863k     Document Type: Article

References (39)

1. A. J. Miller M. C. Mihm Jr Melanoma N. Engl. J. Med. 2006 355 51 65
2. J. A. Curtin J. Fridlyand T. Kageshita H. N. Patel K. J. Busam H. Kutzner K. H. Cho S. Aiba E. B. Brocker P. E. LeBoit D. Pinkel B. C. Bastian Distinct sets of genetic alterations in melanoma N. Engl. J. Med. 2005 353 2135 47
3. R. K. Thomas A. C. Baker R. M. Debiasi W. Winckler T. Laframboise W. M. Lin M. Wang W. Feng T. Zander L. MacConaill J. C. Lee R. Nicoletti C. Hatton M. Goyette L. Girard, et al. High-throughput oncogene mutation profiling in human cancer Nat. Genet. 2007 39 347 51
4. V. Gray-Schopfer C. Wellbrock R. Marais Melanoma biology and new targeted therapy Nature 2007 445 851 57
5. L. Chin The genetics of malignant melanoma: lessons from mouse and man Nat. Rev. Cancer 2003 3 559 70
6. J. Jaeger D. Koczan H. J. Thiesen S. M. Ibrahim G. Gross R. Spang M. Kunz Gene expression signatures for tumour progression, tumour subtype, and tumour thickness in laser-microdissected melanoma tissues Clin. Cancer Res. 2007 13 806 15
7. H. Hermeking The 14-3-3 cancer connection Nat. Rev. Cancer 2003 3 931 43
8. H. Hermeking A. Benzinger 14-3-3 proteins in cell cycle regulation Semin. Cancer Biol. 2006 16 183 92
9. H. Hermeking C. Lengauer K. Polyak T. C. He L. Zhang S. Thiagalingam K. W. Kinzler B. Vogelstein 14-3-3σ is a p53-regulated inhibitor of G2/M progression Mol. Cell 1997 1 3 11
10. A. Benzinger N. Muster H. B. Koch J. R. Yates, 3rd H. Hermeking Targeted proteomic analysis of 14-3-3σ, a p53 effector commonly silenced in cancer Mol. Cell. Proteomics 2005 4 785 95
11. A. J. Levine p53, the cellular gatekeeper for growth and division Cell 1997 88 323 31
12. H. Y. Yang Y. Y. Wen C. H. Chen G. Lozano M. H. Lee 14-3-3σ positively regulates p53 and suppresses tumour growth Mol. Cell. Biol. 2003 23 7096 7107
13. H. Y. Yang Y. Y. Wen Y. I. Lin L. Pham C. H. Su H. Yang J. Chen M. H. Lee Roles for negative cell regulator 14-3-3σ in control of MDM2 activities Oncogene 2007 26 52 7355 62
14. T. A. Chan H. Hermeking C. Lengauer K. W. Kinzler B. Vogelstein 14-3-3σ is required to prevent mitotic catastrophe after DNA damage Nature 1999 401 616 20
15. A. T. Ferguson E. Evron C. B. Umbricht T. K. Pandita T. A. Chan H. Hermeking J. R. Marks A. R. Lambers P. A. Futreal M. R. Stampfer S. Sukumar High frequency of hypermethylation at the 14-3-3σ locus leads to gene silencing in breast cancer Proc. Natl. Acad. Sci. U. S. A. 2000 97 6049 54
16. N. Iwata H. Yamamoto S. Sasaki F. Itoh H. Suzuki T. Kikuchi H. Kaneto S. Iku I. Ozeki Y. Karino T. Satoh J. Toyota M. Satoh T. Endo K. Imai Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3σ gene in human hepatocellular carcinoma Oncogene 2000 19 46 5298 5302
17. P. Mhawech A. Benz C. Cerato V. Greloz M. Assaly J. C. Desmond H. P. Koeffler D. Lodygin H. Hermeking F. Herrmann J. Schwaller Downregulation of 14-3-3σ in ovary, prostate and endometrial carcinomas is associated with CpG island methylation Mod. Pathol. 2005 18 3 340 48
18. D. Lodygin J. Diebold H. Hermeking Prostate cancer is characterized by epigenetic silencing of 14-3-3σ expression Oncogene 2004 23 56 9034 41
19. J. Schultz S. M. Ibrahim J. Vera M. Kunz 14-3-3σ gene silencing during melanoma progression and its role in cell cycle control and cellular senescence Mol. Cancer 2009 8 53
20. R. Lev Bar-Or R. Maya L. A. Segel U. Alon A. J. Levine M. Oren Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study Proc. Natl. Acad. Sci. U. S. A. 2000 97 21 11250 55
21. G. Lahav N. Rosenfeld A. Sigal N. Geva-Zatorsky A. J. Levine M. B. Elowitz U. Alon Dynamics of the p53-Mdm2 feedback loop in individual cells Nat. Genet. 2004 36 2 147 50
22. N. Geva-Zatorsky N. Rosenfeld S. Itzkovitz R. Milo A. Sigal E. Dekel T. Yarnitzky Y. Liron P. Polak G. Lahav U. Alon Oscillations and variability in the p53 system Mol. Syst. Biol. 2006 2 2006.0033
23. L. Ma J. Wagner J. J. Rice W. Hu A. J. Levine G. A. Stolovitzky A plausible model for the digital response of p53 to DNA damage Proc. Natl. Acad. Sci. U. S. A. 2005 102 40 14266 71
24. S. Ramalingam P. Honkanen L. Young T. Shimura J. Austin P. S. Steeg S. Nishizuka Quantitative assessment of the p53-Mdm2 feedback loop using protein lysate microarrays Cancer Res. 2007 67 13 6247 52
25. K. Puszyński B. Hat T. Lipniacki Oscillations and bistability in the stochastic model of p53 regulation J. Theor. Biol. 2008 254 2 452 65
26. M. S. Soengas P. Capodieci D. Polsky J. Mora M. Esteller X. Opitz-Araya R. McCombie J. G. Herman W. L. Gerald Y. A. Lazebnik C. Cordón- Cardó S. W. Lowe Inactivation of the apoptosis effector Apaf-1 in malignant melanoma Nature 2001 409 207 11
27. M. Schilling T. Maiwald S. Bohl M. Kollmann C. Kreutz J. Timmer U. Klingmüller Computational processing and error reduction strategies for standardized quantitative data in biological networks FEBS J. 2005 272 6400 11
28. D. W. Bartlett M. E. Davis Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging Nucleic Acids Res. 2006 34 1 322 33
29. J. Vera E. Balsa-Canto P. Wellstead J. R. Banga O. Wolkenhauer Power-Law Models of Signal Transduction Pathways Cell. Signalling 2007 19 1531 41
30. S. Nikolov J. Vera V. Kotev O. Wolkenhauer V. Petrov Dynamic properties of a delayed protein cross talk model BioSystems 2008 91 1 51 68
31. T. Urano T. Saito T. Tsukui M. Fujita T. Hosoi M. Muramatsu Y. Ouchi S. Inoue Efp targets 14-3-3σ for proteolysis and promotes breast tumour growth Nature 2002 417 6891 871 75
32. M. D. Abramoff P. J. Magelhaes S. J. Ram Image Processing with ImageJ Biophotonics International 2004 11 7 36 42
33. M. J. van Hemert M. Niemantsverdriet T. Schmidt C. Backendorf H. P. Spaink Isoform-specific differences in rapid nucleocytoplasmic shuttling cause distinct subcellular distributions of 14-3-3σ and 14-3-3ζ J. Cell Sci. 2004 117 8 1411 20
34. H. Schmidt M. Jirstrand Systems Biology Toolbox for MATLAB: a computational platform for research in systems biology Bioinformatics 2006 22 4 514 15
35. L. W. Elmore C. W. Rehder X. Di P. A. McChesney C. K. Jackson-Cook D. A. Gewirtz S. E. Holt Adriamycin-induced senescence in breast tumour cells involves functional p53 and telomere dysfunction J. Biol. Chem. 2002 277 35509 15
36. S. R. Schwarze V. X. Fu J. A. Desotelle M. L. Kenowski D. F. Jarrard The identification of senescence-specific genes during the induction of senescence in prostate cancer cells Neoplasia 2005 7 816 23
37. S. Liang Y. Xu G. Shen X. Zhao J. Zhou X. Li F. Gong B. Ling L. Fang C. Huang Y. Wei Gene expression and methylation status of 14-3-3σ in human renal carcinoma tissues IUBMB Life 2008 60 534 40
38. U. K. Bhawal K. Tsukinoki T. Sasahira F. Sato Y. Mori N. Muto M. Sugiyama H. Kuniyasu Methylation and intratumoural heterogeneity of 14-3-3σ in oral cancer Oncol. Rep. 2007 18 4 817 24
39. M. Gasco A. K. Bell V. Heath A. Sullivan P. Smith L. Hiller I. Yulug G. Numico M. Merlano P. J. Farrell M. Tavassoli B. Gusterson T. Crook Epigenetic inactivation of 14-3-3σ in oral carcinoma association with p16(INK4a) silencing and human papillomavirus negativity Cancer Res. 2002 62 2072 76