메뉴 건너뛰기




Volumn 13, Issue 9 B, 2009, Pages 4002-4013

Membrane-type 4 matrix metalloproteinase (MT4-MMP) induces lung metastasis by alteration of primary breast tumour vascular architecture

Author keywords

Angiogenesis; Breast cancer; Metastasis; MT MMP; Vessel architecture

Indexed keywords

MATRIX METALLOPROTEINASE 17;

EID: 72949089968     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2009.00764.x     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 34249951148 scopus 로고    scopus 로고
    • Regional lymph node metastases; a singular manifestation of the process of clinical metastases in cancer: contemporary animal research and clinical reports suggest unifying concepts
    • Cady B. Regional lymph node metastases; a singular manifestation of the process of clinical metastases in cancer: contemporary animal research and clinical reports suggest unifying concepts. Ann. Surg. Oncol. 2007, 14:1790-1800.
    • (2007) Ann. Surg. Oncol. , vol.14 , pp. 1790-1800
    • Cady, B.1
  • 2
    • 5444219883 scopus 로고    scopus 로고
    • Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies
    • Folgueras AR, Pendas AM, Sanchez LM. Matrix metalloproteinases in cancer: from new functions to improved inhibition strategies. Int. J Dev. Biol. 2004, 48:411-24.
    • (2004) Int. J Dev. Biol. , vol.48 , pp. 411-424
    • Folgueras, A.R.1    Pendas, A.M.2    Sanchez, L.M.3    et al4
  • 3
    • 34250312341 scopus 로고    scopus 로고
    • The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases
    • Cauwe B, Van den Steen PE, Opdenakker G. The biochemical, biological, and pathological kaleidoscope of cell surface substrates processed by matrix metalloproteinases. Crit Rev Biochem Mol Biol. 2007, 42:113-85.
    • (2007) Crit Rev Biochem Mol Biol. , vol.42 , pp. 113-185
    • Cauwe, B.1    Van den Steen, P.E.2    Opdenakker, G.3
  • 4
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • Egeblad M, Werb Z. New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer. 2002, 2:161-74.
    • (2002) Nat Rev Cancer. , vol.2 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 5
    • 36348957365 scopus 로고    scopus 로고
    • Breast cancer progression: insights into multifaceted matrix metalloproteinases
    • Chabottaux V, Noel A. Breast cancer progression: insights into multifaceted matrix metalloproteinases. Clin. Exp. Metastasis. 2007, 24:647-56.
    • (2007) Clin. Exp. Metastasis. , vol.24 , pp. 647-656
    • Chabottaux, V.1    Noel, A.2
  • 6
    • 36348989961 scopus 로고    scopus 로고
    • Matrix metalloproteinases to predict breast cancer metastases
    • Chabottaux V, Noel A. Matrix metalloproteinases to predict breast cancer metastases. Clin. Lab. Int. 2007, 31:8-10.
    • (2007) Clin. Lab. Int. , vol.31 , pp. 8-10
    • Chabottaux, V.1    Noel, A.2
  • 7
    • 20344361933 scopus 로고    scopus 로고
    • Metalloproteinases and their inhibitors in tumor angiogenesis
    • Handsley MM, Edwards DR. Metalloproteinases and their inhibitors in tumor angiogenesis. Int. J. Cancer. 2005, 115:849-60.
    • (2005) Int. J. Cancer. , vol.115 , pp. 849-860
    • Handsley, M.M.1    Edwards, D.R.2
  • 8
    • 42349114587 scopus 로고    scopus 로고
    • Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead
    • van Hinsbergh VW, Koolwijk P. Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead. Cardiovasc. Res. 2008, 78:203-12.
    • (2008) Cardiovasc. Res. , vol.78 , pp. 203-212
    • van Hinsbergh, V.W.1    Koolwijk, P.2
  • 10
    • 15244352321 scopus 로고    scopus 로고
    • Membrane type-matrix metalloproteinases and tumor progression
    • Sounni NE, Noel A. Membrane type-matrix metalloproteinases and tumor progression. Biochimie. 2005, 87:329-42.
    • (2005) Biochimie. , vol.87 , pp. 329-342
    • Sounni, N.E.1    Noel, A.2
  • 11
    • 43049084341 scopus 로고    scopus 로고
    • MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer
    • Sohail A, Sun Q, Zhao H. MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancer. Cancer Metastasis Rev. 2008, 27:289-302.
    • (2008) Cancer Metastasis Rev. , vol.27 , pp. 289-302
    • Sohail, A.1    Sun, Q.2    Zhao, H.3    et al4
  • 12
    • 0030022539 scopus 로고    scopus 로고
    • Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma
    • Puente XS, Pendas AM, Llano E. Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res. 1996, 56:944-9.
    • (1996) Cancer Res. , vol.56 , pp. 944-949
    • Puente, X.S.1    Pendas, A.M.2    Llano, E.3    et al4
  • 13
    • 0032878233 scopus 로고    scopus 로고
    • Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts
    • Kajita M, Kinoh H, Ito N. Human membrane type-4 matrix metalloproteinase (MT4-MMP) is encoded by a novel major transcript: isolation of complementary DNA clones for human and mouse mt4-mmp transcripts. FEBS Lett. 1999, 457:353-6.
    • (1999) FEBS Lett. , vol.457 , pp. 353-356
    • Kajita, M.1    Kinoh, H.2    Ito, N.3    et al4
  • 14
    • 34548403035 scopus 로고    scopus 로고
    • Establishment of an MT4-MMP-deficient mouse strain representing an efficient tracking system for MT4-MMP/MMP-17 expression in vivo using beta-galactosidase
    • Rikimaru A, Komori K, Sakamoto T. Establishment of an MT4-MMP-deficient mouse strain representing an efficient tracking system for MT4-MMP/MMP-17 expression in vivo using beta-galactosidase. Genes Cells. 2007, 12:1091-100.
    • (2007) Genes Cells. , vol.12 , pp. 1091-1100
    • Rikimaru, A.1    Komori, K.2    Sakamoto, T.3    et al4
  • 15
    • 0032919387 scopus 로고    scopus 로고
    • Overview of expression of matrix metalloproteinases (MMP-17, MMP-18, and MMP-20) in cultured human cells
    • Grant GM, Giambernardi TA, Grant AM. Overview of expression of matrix metalloproteinases (MMP-17, MMP-18, and MMP-20) in cultured human cells. Matrix Biol. 1999, 18:145-8.
    • (1999) Matrix Biol. , vol.18 , pp. 145-148
    • Grant, G.M.1    Giambernardi, T.A.2    Grant, A.M.3    et al4
  • 16
    • 0037359601 scopus 로고    scopus 로고
    • Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells
    • Nuttall RK, Pennington CJ, Taplin J. Elevated membrane-type matrix metalloproteinases in gliomas revealed by profiling proteases and inhibitors in human cancer cells. Mol. Cancer Res. 2003, 1:333-45.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 333-345
    • Nuttall, R.K.1    Pennington, C.J.2    Taplin, J.3    et al4
  • 17
    • 22044445706 scopus 로고    scopus 로고
    • Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues
    • Riddick AC, Shukla CJ, Pennington CJ. Identification of degradome components associated with prostate cancer progression by expression analysis of human prostatic tissues. Br. J. Cancer. 2005, 92:2171-80.
    • (2005) Br. J. Cancer. , vol.92 , pp. 2171-2180
    • Riddick, A.C.1    Shukla, C.J.2    Pennington, C.J.3    et al4
  • 18
    • 33744934515 scopus 로고    scopus 로고
    • Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases
    • Chabottaux V, Sounni NE, Pennington CJ. Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Res. 2006, 66:5165-72.
    • (2006) Cancer Res. , vol.66 , pp. 5165-5172
    • Chabottaux, V.1    Sounni, N.E.2    Pennington, C.J.3    et al4
  • 19
    • 0034640282 scopus 로고    scopus 로고
    • Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2
    • English WR, Puente XS, Freije JM. Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2. J. Biol. Chem. 2000, 275:14046-55.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14046-14055
    • English, W.R.1    Puente, X.S.2    Freije, J.M.3    et al4
  • 20
    • 1042301387 scopus 로고    scopus 로고
    • The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells
    • Rozanov DV, Hahn-Dantona E, Strickland DK. The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells. J. Biol. Chem. 2004, 279:4260-8.
    • (2004) J. Biol. Chem. , vol.279 , pp. 4260-4268
    • Rozanov, D.V.1    Hahn-Dantona, E.2    Strickland, D.K.3    et al4
  • 21
    • 1642354112 scopus 로고    scopus 로고
    • ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1
    • Gao G, Plaas A, Thompson VP. ADAMTS4 (aggrecanase-1) activation on the cell surface involves C-terminal cleavage by glycosylphosphatidyl inositol-anchored membrane type 4-matrix metalloproteinase and binding of the activated proteinase to chondroitin sulfate and heparan sulfate on syndecan-1. J. Biol. Chem. 2004, 279:10042-51.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10042-10051
    • Gao, G.1    Plaas, A.2    Thompson, V.P.3    et al4
  • 22
    • 33646377855 scopus 로고    scopus 로고
    • ADAMTS5-mediated aggrecanolysis in murine epiphyseal chondrocyte cultures
    • Stewart MC, Fosang AJ, Bai Y. ADAMTS5-mediated aggrecanolysis in murine epiphyseal chondrocyte cultures. Osteoarthritis. Cartilage. 2006, 14:392-402.
    • (2006) Osteoarthritis. Cartilage. , vol.14 , pp. 392-402
    • Stewart, M.C.1    Fosang, A.J.2    Bai, Y.3    et al4
  • 23
    • 0033839080 scopus 로고    scopus 로고
    • Openings between defective endothelial cells explain tumor vessel leakiness
    • Hashizume H, Baluk P, Morikawa S. Openings between defective endothelial cells explain tumor vessel leakiness. Am. J. Pathol. 2000, 156:1363-80.
    • (2000) Am. J. Pathol. , vol.156 , pp. 1363-1380
    • Hashizume, H.1    Baluk, P.2    Morikawa, S.3    et al4
  • 24
    • 33947626578 scopus 로고    scopus 로고
    • Sentinel lymph node imaging using quantum dots in mouse tumor models
    • Ballou B, Ernst LA, Andreko S. Sentinel lymph node imaging using quantum dots in mouse tumor models. Bioconjug. Chem. 2007, 18:389-96.
    • (2007) Bioconjug. Chem. , vol.18 , pp. 389-396
    • Ballou, B.1    Ernst, L.A.2    Andreko, S.3    et al4
  • 25
    • 0036124520 scopus 로고    scopus 로고
    • Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
    • Morikawa S, Baluk P, Kaidoh T. Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 2002, 160:985-1000.
    • (2002) Am. J. Pathol. , vol.160 , pp. 985-1000
    • Morikawa, S.1    Baluk, P.2    Kaidoh, T.3    et al4
  • 26
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
    • Maeda H, Wu J, Sawa T. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control Release. 2000, 65:271-84.
    • (2000) J. Control Release. , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    et al4
  • 27
    • 34547653668 scopus 로고    scopus 로고
    • Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines
    • Greish K. Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines. J. Drug Target. 2007, 15:457-64.
    • (2007) J. Drug Target. , vol.15 , pp. 457-464
    • Greish, K.1
  • 28
    • 0036674501 scopus 로고    scopus 로고
    • Dissemintation and growth of cancer cells in metastatic sites
    • Chambers AF, Groom AC, MacDonald IC. Dissemintation and growth of cancer cells in metastatic sites. Nat. Rev. Cancer. 2002, 2:563-72.
    • (2002) Nat. Rev. Cancer. , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 29
    • 0032493871 scopus 로고    scopus 로고
    • Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay
    • Kim J, Yu W, Kovalski K. Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell. 1998, 94:353-62.
    • (1998) Cell. , vol.94 , pp. 353-362
    • Kim, J.1    Yu, W.2    Kovalski, K.3    et al4
  • 30
    • 0032816631 scopus 로고    scopus 로고
    • Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers
    • Adachi Y, Yamamoto H, Itoh F. Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers. Gut. 1999, 45:252-8.
    • (1999) Gut. , vol.45 , pp. 252-258
    • Adachi, Y.1    Yamamoto, H.2    Itoh, F.3    et al4
  • 31
    • 1642268124 scopus 로고    scopus 로고
    • Altered metastatic behavior of human breast cancer cells after experimental manipulation of matrix metalloproteinase 8 gene expression
    • Montel V, Kleeman J, Agarwal D. Altered metastatic behavior of human breast cancer cells after experimental manipulation of matrix metalloproteinase 8 gene expression. Cancer Research. 2004, 64:1687-94.
    • (2004) Cancer Research. , vol.64 , pp. 1687-1694
    • Montel, V.1    Kleeman, J.2    Agarwal, D.3    et al4
  • 32
    • 16844383171 scopus 로고    scopus 로고
    • Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis
    • Cao J, Chiarelli C, Kozarekar P. Membrane type 1-matrix metalloproteinase promotes human prostate cancer invasion and metastasis. Thromb. Haemost. 2005, 93:770-8.
    • (2005) Thromb. Haemost. , vol.93 , pp. 770-778
    • Cao, J.1    Chiarelli, C.2    Kozarekar, P.3    et al4
  • 33
    • 0034194578 scopus 로고    scopus 로고
    • A critical step in metastasis: in vivo analysis of intravasation at the primary tumor
    • Wyckoff JB, Jones JG, Condeelis JS. A critical step in metastasis: in vivo analysis of intravasation at the primary tumor. Cancer Res. 2000, 60:2504-11.
    • (2000) Cancer Res. , vol.60 , pp. 2504-2511
    • Wyckoff, J.B.1    Jones, J.G.2    Condeelis, J.S.3    et al4
  • 34
    • 0029784472 scopus 로고    scopus 로고
    • Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well
    • Koop S, Schmidt EE, MacDonald IC. Independence of metastatic ability and extravasation: metastatic ras-transformed and control fibroblasts extravasate equally well. Proc. Natl. Acad. Sci. USA. 1996, 93:11080-4.
    • (1996) Proc. Natl. Acad. Sci. USA. , vol.93 , pp. 11080-11084
    • Koop, S.1    Schmidt, E.E.2    MacDonald, I.C.3    et al4
  • 36
    • 38649107709 scopus 로고    scopus 로고
    • Pericytes: gatekeepers in tumour cell metastasis
    • Gerhardt H, Semb H. Pericytes: gatekeepers in tumour cell metastasis. J. Mol. Med. 2008, 86:135-44.
    • (2008) J. Mol. Med. , vol.86 , pp. 135-144
    • Gerhardt, H.1    Semb, H.2
  • 37
    • 0035887187 scopus 로고    scopus 로고
    • Structural fragility of blood vessels and peritoneum in calponin h1-deficient mice, resulting in an increase in hematogenous metastasis and peritoneal dissemination of malignant tumor cells
    • Taniguchi S, Takeoka M, Ehara T. Structural fragility of blood vessels and peritoneum in calponin h1-deficient mice, resulting in an increase in hematogenous metastasis and peritoneal dissemination of malignant tumor cells. Cancer Res. 2001, 61:7627-34.
    • (2001) Cancer Res. , vol.61 , pp. 7627-7634
    • Taniguchi, S.1    Takeoka, M.2    Ehara, T.3    et al4
  • 38
    • 8744221615 scopus 로고    scopus 로고
    • Involvement of membrane-type matrix metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial cells: Role of MT3-MMP
    • Plaisier M, Kapiteijn K, Koolwijk P. Involvement of membrane-type matrix metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial cells: Role of MT3-MMP. J. Clin. Endocrinol. Metab. 2004, 89:5828-36.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 5828-5836
    • Plaisier, M.1    Kapiteijn, K.2    Koolwijk, P.3    et al4
  • 39
    • 33645101246 scopus 로고    scopus 로고
    • Membrane-type matrix metalloproteinases and vascularization in human endometrium during the menstrual cycle
    • Plaisier M, Koolwijk P, Hanemaaijer R. Membrane-type matrix metalloproteinases and vascularization in human endometrium during the menstrual cycle. Mol. Hum. Reprod. 2006, 12:11-8.
    • (2006) Mol. Hum. Reprod. , vol.12 , pp. 11-18
    • Plaisier, M.1    Koolwijk, P.2    Hanemaaijer, R.3    et al4
  • 40
    • 40449103297 scopus 로고    scopus 로고
    • A human breast cell model of preinvasive to invasive transition
    • Rizki A, Weaver VM, Lee SY. A human breast cell model of preinvasive to invasive transition. Cancer Res. 2008, 68:1378-87.
    • (2008) Cancer Res. , vol.68 , pp. 1378-1387
    • Rizki, A.1    Weaver, V.M.2    Lee, S.Y.3    et al4
  • 41
    • 0032722873 scopus 로고    scopus 로고
    • Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain
    • Wang Y, Johnson AR, Ye QZ. Catalytic activities and substrate specificity of the human membrane type 4 matrix metalloproteinase catalytic domain. J. Biol. Chem. 1999, 274:33043-9.
    • (1999) J. Biol. Chem. , vol.274 , pp. 33043-33049
    • Wang, Y.1    Johnson, A.R.2    Ye, Q.Z.3    et al4
  • 42
    • 0032864044 scopus 로고    scopus 로고
    • Biochemical characterization of the catalytic domain of membrane-type 4 matrix metalloproteinase
    • Kolkenbrock H, Essers L, Ulbrich N. Biochemical characterization of the catalytic domain of membrane-type 4 matrix metalloproteinase. Biol. Chem. 1999, 380:1103-8.
    • (1999) Biol. Chem. , vol.380 , pp. 1103-1108
    • Kolkenbrock, H.1    Essers, L.2    Ulbrich, N.3    et al4
  • 43
    • 31144442936 scopus 로고    scopus 로고
    • Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases
    • Chantrain CF, Henriet P, Jodele S. Mechanisms of pericyte recruitment in tumour angiogenesis: a new role for metalloproteinases. Eur. J. Cancer. 2006, 42:310-8.
    • (2006) Eur. J. Cancer. , vol.42 , pp. 310-318
    • Chantrain, C.F.1    Henriet, P.2    Jodele, S.3    et al4
  • 44
    • 17144430502 scopus 로고    scopus 로고
    • The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent
    • Jodele S, Chantrain CF, Blavier L. The contribution of bone marrow-derived cells to the tumor vasculature in neuroblastoma is matrix metalloproteinase-9 dependent. Cancer Res. 2005, 65:3200-8.
    • (2005) Cancer Res. , vol.65 , pp. 3200-3208
    • Jodele, S.1    Chantrain, C.F.2    Blavier, L.3    et al4
  • 45
    • 17444393268 scopus 로고    scopus 로고
    • An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature
    • Lehti K, Allen E, Birkedal-Hansen H. An MT1-MMP-PDGF receptor-beta axis regulates mural cell investment of the microvasculature. Genes Dev. 2005, 19:979-91.
    • (2005) Genes Dev. , vol.19 , pp. 979-991
    • Lehti, K.1    Allen, E.2    Birkedal-Hansen, H.3    et al4
  • 46
    • 2442506936 scopus 로고    scopus 로고
    • Cleavage of focal adhesion kinase in vascular smooth muscle cells overexpressing membrane-type matrix metalloproteinases
    • Shofuda T, Shofuda K, Ferri N. Cleavage of focal adhesion kinase in vascular smooth muscle cells overexpressing membrane-type matrix metalloproteinases. Arterioscler. Thromb. Vasc. Biol. 2004, 24:839-44.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 839-844
    • Shofuda, T.1    Shofuda, K.2    Ferri, N.3    et al4
  • 48
    • 30744432102 scopus 로고    scopus 로고
    • Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo
    • Chen J, Somanath PR, Razorenova O. Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo. Nat. Med. 2005, 11:1188-96.
    • (2005) Nat. Med. , vol.11 , pp. 1188-1196
    • Chen, J.1    Somanath, P.R.2    Razorenova, O.3    et al4
  • 49
    • 0035355471 scopus 로고    scopus 로고
    • Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism
    • Hawighorst T, Velasco P, Streit M. Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. EMBO J. 2001, 20:2631-40.
    • (2001) EMBO J. , vol.20 , pp. 2631-2640
    • Hawighorst, T.1    Velasco, P.2    Streit, M.3    et al4
  • 50
    • 27144541479 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model
    • Fears CY, Grammer JR, Stewart JE. Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model. Cancer Res. 2005, 65:9338-46.
    • (2005) Cancer Res. , vol.65 , pp. 9338-9346
    • Fears, C.Y.1    Grammer, J.R.2    Stewart, J.E.3    et al4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.