Outcome of acute liver failure in the elderly

Liver Transplantation

Volumn 15, Issue 11, 2009, Pages 1481-1487

  Schiødt, Frank V ^a,b   Chung, Raymond T ^c   Schilsky, Michael L ^d,h   Hay, J Eileen ^e   Christensen, Erik ^b   Lee, William M ^a   Ostapowicz, George A ^a   Polson, Julie ^a   Larson, Anne M ^f   Davern, Timothy ^g   McCashland, Timothy ⁱ   Murray, Natalie ^j   Shaikh, A Obaid S ^k   Blei, Andres ^l   Zaman, Atif ^m   Han, Steven H B ⁿ   Fontana, Robert ^o   McGuire, Brendan ^p   Chung, Ray ^c   Smith, Alastair ^q   Brown, Robert ^r   Crippin, Jeffrey ^s   Harrison, Edwin ^t   Reuben, Adrian ^u   Munoz, Santiago ^v   Reddy, Rajender ^w   Stravitz, R Todd ^x   Rossaro, Lorenzo ^y   Satyanarayana, Raj ^z   Hassanein, Tarek ^aa   more..

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b BISPEBJERG HOSPITAL   (Denmark)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Yale New Haven Transplantation Center   (United States)

^e MAYO CLINIC   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

^g UNIVERSITY OF CALIFORNIA   (United States)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

ⁱ UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^j BAYLOR UNIVERSITY MEDICAL CENTER   (United States)

^k UNIVERSITY OF PITTSBURGH   (United States)

^l NORTHWESTERN UNIVERSITY   (United States)

^m UNIVERSITY OF OREGON   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o UNIVERSITY OF MICHIGAN   (United States)

^p UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^q DUKE UNIVERSITY MEDICAL CENTER   (United States)

^r Och Spine at New York Presbyterian Hospitals   (United States)

^s WASHINGTON UNIVERSITY   (United States)

^t MAYO CLINIC   (United States)

^u MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^v ALBERT EINSTEIN MEDICAL CENTER   (United States)

^w UNIVERSITY OF PENNSYLVANIA   (United States)

^x VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^y UNIVERSITY OF CALIFORNIA   (United States)

^z MAYO CLINIC   (United States)

^aa UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

PARACETAMOL;

ADOLESCENT; ADULT; AGE; AGE DISTRIBUTION; AGED; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; AUTOIMMUNE HEPATITIS; BUDD CHIARI SYNDROME; CONTROLLED STUDY; FEMALE; HEPATITIS A; HEPATITIS B; HUMAN; LIVER FAILURE; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL RATE; WILSON DISEASE;

ACETAMINOPHEN; ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ANALGESICS, NON-NARCOTIC; FEMALE; HUMANS; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; PROGNOSIS; REGISTRIES; SURVIVAL ANALYSIS; YOUNG ADULT;

EID: 72949088803     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.21865     Document Type: Article

References (36)

1. Trey C, Davidson CS. The management of fulminant hepatic failure. In: Popper H, Schaffner F, eds. Progress in Liver Diseases. New York, NY: Grune & Stratton; 1970:282-298.
2. Lee WM, Schiødt FV. Fulminant hepatic failure. In: Schiff ER, Sorrell MF, Maddrey WC, eds. Schiff's Diseases of the Liver. Philadelphia, PA: Lippincott-Raven; 1999:879-895.
3. Lee WM, Squires RH Jr, Nyberg SL, Doo E, Hoofnagle JH. Acute liver failure: summary of a workshop. Hepatology 2008;47:1401-1415. (Pubitemid 351547926)
4. Ostapowicz G, Lee WM. Acute hepatic failure: a Western perspective. J Gastroenterol Hepatol 2000;15:480-488. (Pubitemid 30327048)
5. Schiødt FV, Lee WM. Fulminant liver disease. Clin Liver Dis 2003;7:331-349, vi.
6. Rutherford A, Chung RT. Acute liver failure: mechanisms of hepatocyte injury and regeneration. Semin Liver Dis 2008;28:167-174. (Pubitemid 351632956)
7. Schiødt FV, Atillasoy E, Shakil AO, Schiff ER, Caldwell C, Kowdley KV, et al. Etiology and outcome for 295 patients with acute liver failure in the United States. Liver Transpl Surg 1999;5:29-34. (Pubitemid 29037351)
8. Ostapowicz G, Fontana RJ, Schiødt FV, Larson A, Davern TJ, Han SH, et al. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 2002;137:947-954. (Pubitemid 35440240)
9. Polson J. Assessment of prognosis in acute liver failure. Semin Liver Dis 2008;28:218-225. (Pubitemid 351632961)
10. O'Grady JG, Alexander GJ, Hayllar KM, Williams R. Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 1989;97:439-445. (Pubitemid 19192181)
11. Dhiman RK, Jain S, Maheshwari U, Bhalla A, Sharma N, Ahluwalia J, et al. Early indicators of prognosis in fulminant hepatic failure: an assessment of the Model for End-Stage Liver Disease (MELD) and King's College Hospital criteria. Liver Transpl 2007;13:814-821. (Pubitemid 46939435)
12. Dhiman RK, Seth AK, Jain S, Chawla YK, Dilawari JB. Prognostic evaluation of early indicators in fulminant hepatic failure by multivariate analysis. Dig Dis Sci 1998;43:1311-1316. (Pubitemid 28272568)
13. Zeeh J, Platt D. The aging liver: structural and functional changes and their consequences for drug treatment in old age. Gerontology 2002;48:121-127. (Pubitemid 34310065)
14. Wynne HA, Cope LH, Mutch E, Rawlins MD, Woodhouse KW, James OF. The effect of age upon liver volume and apparentliverbloodflowinhealthyman. Hepatology1989;9:297-301.
15. Iber FL, Murphy PA, Connor ES. Age-related changes in the gastrointestinal system. Effects on drug therapy. Drugs Aging 1994;5:34-48.
16. Fu A, Nair KS. Age effect on fibrinogen and albumin synthesis in humans. Am J Physiol 1998;275(pt 1):E1023-E1030. (Pubitemid 29025072)
17. Collins BH, Pirsch JD, Becker YT, Hanaway MJ, Van der Werf WJ, D'Alessandro AM, et al. Long-term results of liver transplantation in older patients 60 years of age and older. Transplantation 2000;70:780-783.
18. Levy MF, Somasundar PS, Jennings LW, Jung GJ, Molmenti EP, Fasola CG, et al. The elderly liver transplant recipient: a call for caution. Ann Surg 2001;233:107-113. (Pubitemid 32042780)
19. Herrero JI, Lucena JF, Quiroga J, Sangro B, Pardo F, Rotellar F, et al. Liver transplant recipients older than 60 years have lower survival and higher incidence of malignancy. Am J Transplant 2003;3:1407-1412. (Pubitemid 37288086)
20. Keswani RN, Ahmed A, Keeffe EB. Older age and liver transplantation: a review. Liver Transpl 2004;10:957-967. (Pubitemid 39232748)
21. Larson AM, Polson J, Fontana RJ, Davern TJ, Lalani E, Hynan LS, et al. Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. Hepatology 2005;42:1364-1372. (Pubitemid 43260039)
22. Schiødt FV, Ostapowicz G, Murray N, Satyanarana R, Zaman A, Munoz S, et al. Alpha-fetoprotein and prognosis in acute liver failure. Liver Transpl 2006;12:1776-1781. (Pubitemid 44911803)
23. Schmidt LE. Age and paracetamol self-poisoning. Gut 2005;54:686-690.
24. Barshes NR, Lee TC, Balkrishnan R, Karpen SJ, Carter BA, Goss JA. Risk stratification of adult patients undergoing orthotopic liver transplantation for fulminant hepatic failure. Transplantation 2006;81:195-201.
25. Bernal W, Cross TJ, Auzinger G, Sizer E, Heneghan MA, Bowles M, et al. Outcome after wait-listing for emergency liver transplantation in acute liver failure: a single centre experience. J Hepatol 2009;50:306-313.
26. Lipshutz GS, Hiatt J, Ghobrial RM, Farmer DG, Martinez MM, Yersiz H, et al. Outcome of liver transplantation in septuagenarians: a single-center experience. Arch Surg 2007;142:775-781. (Pubitemid 47295742)
27. Cross TJ, Antoniades CG, Muiesan P, Al Chalabi T, Aluvihare V, Agarwal K, et al. Liver transplantation in patients over 60 and 65 years: an evaluation of long-term outcomes and survival. Liver Transpl 2007;13:1382-1388. (Pubitemid 47629570)
28. Schmucker DL. Age-related changes in liver structure and function: implications for disease ? Exp Gerontol 2005;40:650-659.
29. Hoofnagle JH, Lombardero M, Zetterman RK, Lake J, Porayko M, Everhart J, et al. Donor age and outcome of liver transplantation. Hepatology 1996;24:89-96. (Pubitemid 26249418)
30. Anderson CD, Vachharajani N, Doyle M, Lowell JA, Wellen JR, Shenoy S, et al. Advanced donor age alone does not affect patient or graft survival after liver transplantation. J Am Coll Surg 2008;207:847-852.
31. Wakabayashi H, Nishiyama Y, Ushiyama T, Maeba T, Maeta H. Evaluation of the effect of age on functioning hepatocyte mass and liver blood flow using liver scintigraphy in preoperative estimations for surgical patients: comparison with CT volumetry. J Surg Res 2002;106:246-253.
32. Bucher NL, Swaffield MN. The rate of incorporation of labeled thymidine into the deoxyribonucleic acid of regenerating rat liver in relation to the amount of liver excised. Cancer Res 1964;24:1611-1625.
33. Bucher NL, Swaffield MN, Ditroia JF. The influence of age upon the incorporation of thymidine 2-C14 into the DNA of regenerating rat liver. Cancer Res 1964;24:509-512.
34. Cotreau MM, von Moltke LL, Greenblatt DJ. The influence of age and sex on the clearance of cytochrome P450 3A substrates. Clin Pharmacokinet 2005;44:33-60.
35. Marchesini G, Bua V, Brunori A, Bianchi G, Pisi P, Fabbri A, et al. Galactose elimination capacity and liver volume in aging man. Hepatology 1988;8:1079-1083. (Pubitemid 18236606)
36. Schmucker DL. Hepatocyte fine structure during maturation and senescence. J Electron Microsc Tech 1990;14:106-125.