Underestimation of hepatitis C virus genotype 4 RNA levels by the cobas ampliprep/cobas TaQman assay

Hepatology

Volumn 50, Issue 5, 2009, Pages 1681-

  Chevaliez, Stéphane ^a   Fix, Jenna ^a   Soulier, Alexandre ^a   Pawlotsky, Jean Michel ^a  

^a HENRI MONDOR HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS RNA;

5' UNTRANSLATED REGION; AMINO ACID SUBSTITUTION; GENOTYPE; HEPATITIS C VIRUS; HUMAN; INTERMETHOD COMPARISON; INTRAVENOUS DRUG ABUSE; LETTER; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; VIRUS DETECTION; VIRUS LOAD; VIRUS MUTATION;

EID: 72949086417     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23349     Document Type: Letter

References (2)

1. Chevaliez S, Bouvier-Alias M, Brillet R, Pawlotsky JM. Overestimation and underestimation of hepatitis C virus RNA levels in a widely used real-time polymerase chain reaction-based method. HEPATOLOGY 2007;46:22-31.
2. Chevaliez S, Bouvier-Alias M, Castera L, Pawlotsky JM. The Cobas Ampliprep-Cobas TaqMan real-time polymerase chain reaction assay fails to detect hepatitis C virus RNA in highly viremic genotype 4 clinical samples. HEPATOLOGY 2009;49:1397-1398.