Andes virus recognition of human and syrian hamster β3 integrins is determined by an L33P substitution in the PSI domain

Journal of Virology

Volumn 84, Issue 1, 2010, Pages 352-360

  Matthys, Valery S ^a   Gorbunova, Elena E ^a,b   Gavrilovskaya, Irina N ^a,b   Mackow, Erich R ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA3 INTEGRIN; CD51 ANTIGEN; PROLINE; VITRONECTIN;

ANDES VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BETA CHAIN; CELL STRAIN BHK; CHO CELL; CONTROLLED STUDY; COW; ENDOTHELIUM CELL; GENETIC TRANSFECTION; HAMSTER; HANTAVIRUS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MURINAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; VIRUS INFECTION;

AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CATTLE; CELL LINE; CRICETINAE; ENDOTHELIAL CELLS; HANTAVIRUS; HUMANS; INTEGRIN BETA3; MESOCRICETUS; MICE; POLYMORPHISM, GENETIC; RECEPTORS, VIRUS; SPECIES SPECIFICITY;

ANDES VIRUS; BOVINAE; HANTAVIRUS; MESOCRICETUS AURATUS; MURINAE;

EID: 72849150672     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01013-09     Document Type: Article

References (55)

1. Baker, E. K., E. C. Tozer, M. Pfaff, S. J. Shattil, J. C. Loftus, and M. H. Ginsberg. 1997. A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro. Proc. Natl. Acad. Sci. USA 94:1973-1978.
2. 3 integrin through its extracellular domain. J. Biol. Chem. 275:39867-39873.
3. Brakenhielm, E. 2007. Substrate matters: reciprocally stimulatory integrin and VEGF signaling in endothelial cells. Circ. Res. 101:536-538.
4. Chen, J. P., and T. M. Cosgriff. 2000. Hemorrhagic fever virus-induced changes in hemostasis and vascular biology. Blood Coagul. Fibrinolysis 11:461-483.
5. Coller, B. 1997. GPIIb/IIIa antagonists: pathophysiologic and therapeutic insights from studies of c7E3 Fab. Thromb. Haemost. 78:730-735.
6. 3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend. Blood 112:3011-3025.
7. Cosgriff, T. M., H. W. Lee, A. F. See, D. B. Parrish, J. S. Moon, D. J. Kim, and R. M. Lewis. 1991. Platelet dysfunction contributes to the haemostatic defect in haemorrhagic fever with renal syndrome. Trans. R. Soc. Trop. Med. Hyg. 85:660-663.
8. Cosgriff, T. M., and R. M. Lewis. 1991. Mechanisms of disease in hemorrhagic fever with renal syndrome. Kidney Int. Suppl. 35:S72-S79.
9. Denisova, E., W. Dowling, R. LaMonica, R. Shaw, S. Scarlata, F. Ruggeri, and E. R. Mackow. 1999. Rotavirus capsid protein VP5* permeabilizes membranes. J. Virol. 73:3147-3153. (Pubitemid 29135705)
10. Dvorak, H. F., T. M. Sioussat, L. F. Brown, B. Berse, J. A. Nagy, A. Sotrel, E. J. Manseau, L. Van de Water, and D. R. Senger. 1991. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. J. Exp. Med. 174:1275-1278.
11. Enria, D., P. Padula, E. L. Segura, N. Pini, A. Edelstein, C. R. Posse, and M. C. Weissenbacher. 1996. Hantavirus pulmonary syndrome in Argentina: possibility of person to person transmission. Medicina 56:709-711. (Pubitemid 127528617)
12. Galeno, H., J. Mora, E. Villagra, J. Fernandez, J. Hernandez, G. J. Mertz, and E. Ramirez. 2002. First human isolate of hantavirus (Andes virus) in the Americas. Emerg. Infect. Dis. 8:657-661.
13. Gavrilovskaya, I. N., E. J. Brown, M. H. Ginsberg, and E. R. Mackow. 1999. Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by β3 integrins. J. Virol. 73:3951-3959.
14. Gavrilovskaya, I. N., E. E. Gorbunova, N. A. Mackow, and E. R. Mackow. 2008. Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability. J. Virol. 82:5797-5806.
15. Gavrilovskaya, I. N., T. Peresleni, E. Geimonen, and E. R. Mackow. 2002. Pathogenic hantaviruses selectively inhibit beta3 integrin directed endothelial cell migration. Arch. Virol. 147:1913-1931.
16. Gavrilovskaya, I. N., M. Shepley, R. Shaw, M. H. Ginsberg, and E. R. Mackow. 1998. β3 integrins mediate the cellular entry of hantaviruses that cause respiratory failure. Proc. Natl. Acad. Sci. USA 95:7074-7079.
17. Goldsmith, C. S., L. H. Elliott, C. J. Peters, and S. R. Zaki. 1995. Ultrastructural characteristics of Sin Nombre virus, causative agent of hantavirus pulmonary syndrome. Arch. Virol. 140:2107-2122.
18. Hayasaka, D., K. Maeda, F. A. Ennis, and M. Terajima. 2007. Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes. Virus Res. 123:120-127. (Pubitemid 46054332)
19. Hodivala-Dilke, K. M., K. P. McHugh, D. A. Tsakiris, H. Rayburn, D. Crowley, M. Ullman-Cullere, F. P. Ross, B. S. Coller, S. Teitelbaum, and R. O. Hynes. 1999. β3-Integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J. Clin. Investig. 103:229-238.
20. Hooper, J. W., A. M. Ferro, and V. Wahl-Jensen. 2008. Immune serum produced by DNA vaccination protects hamsters against lethal respiratory challenge with Andes virus. J. Virol. 82:1332-1338.
21. Hooper, J. W., T. Larsen, D. M. Custer, and C. S. Schmaljohn. 2001. A lethal disease model for hantavirus pulmonary syndrome. Virology 289:6-14. (Pubitemid 33016232)
22. Hynes, R. O. 2002. Integrins: bidirectional, allosteric signaling machines. Cell 110:673-687.
23. Hynes, R. O., and K. M. Hodivala-Dilke. 1999. Insights and questions arising from studies of a mouse model of Glanzmann thrombasthenia. Thromb. Haemost. 82:481-485.
24. Joutsi-Korhonen, L., S. Preston, P. A. Smethurst, M. Ijsseldijk, E. Schaffner-Reckinger, K. L. Armour, N. A. Watkins, M. R. Clark, P. G. de Groot, R. W. Farndale, W. H. Ouwehand, and L. M. Williamson. 2004. The effect of recombinant IgG antibodies against the leucine-33 form of the platelet β3 integrin (HPA-1a) on platelet function. Thromb. Haemost. 91:743-754.
25. Khaiboullina, S. F., A. A. Rizvanov, V. M. Deyde, and S. C. St Jeor. 2005. Andes virus stimulates interferon-inducible MxA protein expression in endothelial cells. J. Med. Virol. 75:267-275.
26. + T cells in the severity of a fulminant zoonotic viral hemorrhagic fever, hantavirus pulmonary syndrome. J. Immunol. 172:3297-3304.
27. Krakauer, T., J. W. Leduc, and H. Krakauer. 1995. Serum levels of tumor necrosis factor-alpha, interleukin-1, and interleukin-6 in hemorrhagic fever with renal syndrome. Viral Immunol. 8:75-79. (Pubitemid 26025307)
28. Linderholm, M., C. Ahlm, B. Settergren, A. Waage, and A. Tarnvik. 1996. Elevated plasma levels of tumor necrosis factor (TNF)-alpha, soluble TNF receptors, interleukin (IL)-6, and IL-10 in patients with hemorrhagic fever with renal syndrome. J. Infect. Dis. 173:38-43.
29. Liu, Z., M. Gao, Q. Han, S. Lou, and J. Fang. 2009. Platelet glycoprotein IIb/IIIa (HPA-1 and HPA-3) polymorphisms in patients with hemorrhagic fever with renal syndrome. Hum. Immunol. 70:452-456.
30. Luo, B. H., J. Takagi, and T. A. Springer. 2003. Locking the β3 integrin I-like domain into high and low affinity conformations with disulfides. J. Biol. Chem. 279:10215-10221.
31. Mackow, E. R., and I. N. Gavrilovskaya. 2001. Cellular receptors and hantavirus pathogenesis. Curr. Top. Microbiol. Immunol. 256:91-115.
32. Maes, P., J. Clement, P. H. Groeneveld, P. Colson, T. W. Huizinga, and M. Van Ranst. 2006. Tumor necrosis factor-alpha genetic predisposing factors can influence clinical severity in nephropathia epidemica. Viral Immunol. 19:558-564. (Pubitemid 44735067)
33. McElroy, A. K., J. M. Smith, J. W. Hooper, and C. S. Schmaljohn. 2004. Andes virus M genome segment is not sufficient to confer the virulence associated with Andes virus in Syrian hamsters. Virology 326:130-139.
34. Mori, M., A. L. Rothman, I. Kurane, J. M. Montoya, K. B. Nolte, J. E. Norman, D. C. Waite, F. T. Koster, and F. A. Ennis. 1999. High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome. J. Infect. Dis. 179:295-302.
35. Niikura, M., A. Maeda, T. Ikegami, M. Saijo, I. Kurane, and S. Morikawa. 2004. Modification of endothelial cell functions by Hantaan virus infection: prolonged hyper-permeability induced by TNF-alpha of Hantaan virus-infected endothelial cell monolayers. Arch. Virol. 149:1279-1292.
36. Nolte, K. B., R. M. Feddersen, K. Foucar, S. R. Zaki, F. T. Koster, D. Madar, T. L. Merlin, P. J. McFeeley, E. T. Umland, and R. E. Zumwalt. 1995. Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent. Hum. Pathol. 26:110-120.
37. Padula, P. J., A. Edelstein, S. D. Miguel, N. M. Lopez, C. M. Rossi, and R. D. Rabinovich. 1998. Hantavirus pulmonary syndrome outbreak in Argentina: molecular evidence for person-to-person transmission of Andes virus. Virology 241:323-330.
38. Raymond, T., E. Gorbunova, I. N. Gavrilovskaya, and E. R. Mackow. 2005. Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent αvβ3 integrin conformers. Proc. Natl. Acad. Sci. USA 102:1163-1168.
39. Reynolds, L. E., L. Wyder, J. C. Lively, D. Taverna, S. D. Robinson, X. Huang, D. Sheppard, R. O. Hynes, and K. M. Hodivala-Dilke. 2002. Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins. Nat. Med. 8:27-34.
40. Robinson, S. D., L. E. Reynolds, L. Wyder, D. J. Hicklin, and K. M. Hodivala-Dilke. 2004. β3-Integrin regulates vascular endothelial growth factor-A-dependent permeability. Arterioscler. Thromb. Vasc. Biol. 24:2108-2114.
41. Schmaljohn, C., and B. Hjelle. 1997. Hantaviruses: a global disease problem. Emerg. Infect. Dis. 3:95-104.
42. Schmaljohn, C. S. 2001. Bunyaviridae and their replication, p. 1581-1602. In D. M. Knipe and P. M. Howley (ed.), Fields virology, 4th ed. Lippincott-Raven Publishers, Philadelphia, PA.
43. Sun, G. D., X. M. Duan, Y. P. Zhang, Z. Z. Yin, X. L. Niu, Y. F. Li, H. J. Niu, and Y. L. Zhao. 2005. Analysis of genetic polymorphism in randomized donor's HPA 1-16 antigens and establishment of typed platelet donor data bank. Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:889-895. (In Chinese.)
44. Sundstrom, J. B., L. K. McMullan, C. F. Spiropoulou, W. C. Hooper, A. A. Ansari, C. J. Peters, and P. E. Rollin. 2001. Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. J. Virol. 75:6070-6085.
45. Taylor, S. L., N. Frias-Staheli, A. Garcia-Sastre, and C. S. Schmaljohn. 2009. Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor κB. J. Virol. 83:1271-1279.
46. Temonen, M., J. Mustonen, H. Helin, A. Pasternack, A. Vaheri, and H. Holthofer. 1996. Cytokines, adhesion molecules, and cellular infiltration in nephropathia epidemica kidneys: an immunohistochemical study. Clin. Immunol. Immunopathol. 78:47-55.
47. Toro, J., J. D. Vega, A. S. Khan, J. N. Mills, P. Padula, W. Terry, Z. Yadon, R. Valderrama, B. A. Ellis, C. Pavletic, R. Cerda, S. Zaki, W. J. Shieh, R. Meyer, M. Tapia, C. Mansilla, M. Baro, J. A. Vergara, M. Concha, G. Calderon, D. Enria, C. J. Peters, and T. G. Ksiazek. 1998. An outbreak of hantavirus pulmonary syndrome, Chile, 1997. Emerg. Infect. Dis. 4:687-694.
48. Tuvim, M. J., S. E. Evans, C. G. Clement, B. F. Dickey, and B. E. Gilbert. 2009. Augmented lung inflammation protects against influenza A pneumonia. PLoS ONE 4:e4176.
49. van Gils, J. M., J. Stutterheim, T. J. van Duijn, J. J. Zwaginga, L. Porcelijn, M. de Haas, and P. L. Hordijk. 2009. HPA-1a alloantibodies reduce endothelial cell spreading and monolayer integrity. Mol. Immunol. 46:406-415.
50. Wahl-Jensen, V., J. Chapman, L. Asher, R. Fisher, M. Zimmerman, T. Larsen, and J. W. Hooper. 2007. Temporal analysis of Andes virus and Sin Nombre virus infections of Syrian hamsters. J. Virol. 81:7449-7462. (Pubitemid 47047833)
51. Watkins, N. A., P. A. Smethurst, D. Allen, G. A. Smith, and W. H. Ouwehand. 2002. Platelet alphaIIbbeta3 recombinant autoantibodies from the B-cell repertoire of a posttransfusion purpura patient. Br. J. Hematol 116:677-685.
52. Wells, R. M., S. Sosa Estani, Z. E. Yadon, D. Enria, P. Padula, N. Pini, J. N. Mills, C. J. Peters, and E. L. Segura. 1997. An unusual hantavirus outbreak in southern Argentina: person-to-person transmission? Emerg. Infect. Dis. 3:171-174.
53. Xiao, T., J. Takagi, B. S. Coller, J. H. Wang, and T. A. Springer. 2004. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature 432:59-67.
54. Zaki, S., P. Greer, L. Coffield, C. Goldsmith, K. Nolte, K. Foucar, R. Feddersen, R. Zumwalt, G. Miller, P. Rollin, T. Ksiazek, S. Nichol, and C. Peters. 1995. Hantavirus pulmonary syndrome: pathogenesis of an emerging infectious disease. Am. J. Pathol. 146:552-579.
55. Zhu, J., B. H. Luo, T. Xiao, C. Zhang, N. Nishida, and T. A. Springer. 2008. Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces. Mol. Cell 32:849-861.