-
1
-
-
67349152647
-
Treatment in advanced colorectal cancer: What, when and how?
-
Chau I, Cunningham D. Treatment in advanced colorectal cancer: what, when and how? Br J Cancer 2009;100:1704-1719
-
(2009)
Br J Cancer
, vol.100
, pp. 1704-1719
-
-
Chau, I.1
Cunningham, D.2
-
2
-
-
66349093145
-
Chemotherapy with targeted agents for the treatment of metastatic colorectal cancer
-
Köhne CH, Lenz HJ. Chemotherapy with targeted agents for the treatment of metastatic colorectal cancer. Oncologist 2009;14:478-488
-
(2009)
Oncologist
, vol.14
, pp. 478-488
-
-
Köhne, C.H.1
Lenz, H.J.2
-
3
-
-
68949094312
-
Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy
-
Kopetz S, Chang GJ, Overman MJ, et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 2009;27:3677-3683
-
(2009)
J Clin Oncol
, vol.27
, pp. 3677-3683
-
-
Kopetz, S.1
Chang, G.J.2
Overman, M.J.3
-
4
-
-
27244450852
-
OncoSurge: A strategy for improving resectability with curative intent in metastatic colorectal cancer
-
Poston GJ, Adam R, Alberts S, et al. OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. J Clin Oncol 2005;23:7125-7134
-
(2005)
J Clin Oncol
, vol.23
, pp. 7125-7134
-
-
Poston, G.J.1
Adam, R.2
Alberts, S.3
-
5
-
-
33745128778
-
Optimal treatment of metastatic colorectal cancer
-
Pessino A, Sobrero A. Optimal treatment of metastatic colorectal cancer. Expert Rev Anticancer Ther 2006;6:801-812
-
(2006)
Expert Rev Anticancer Ther
, vol.6
, pp. 801-812
-
-
Pessino, A.1
Sobrero, A.2
-
6
-
-
47249124557
-
First-line chemotherapy in metastatic colorectal cancer: New approaches and therapeutic algorithms. Always hit hard first?
-
Loupakis F, Masi G, Vasile E, Falcone A. First-line chemotherapy in metastatic colorectal cancer: new approaches and therapeutic algorithms. Always hit hard first? Curr Opin Oncol 2008;20:459-465
-
(2008)
Curr Opin Oncol
, vol.20
, pp. 459-465
-
-
Loupakis, F.1
Masi, G.2
Vasile, E.3
Falcone, A.4
-
7
-
-
34548242252
-
Presurgical chemotherapy in patients being considered for liver resection
-
Kemeny N. Presurgical chemotherapy in patients being considered for liver resection. Oncologist 2007;12:825-839
-
(2007)
Oncologist
, vol.12
, pp. 825-839
-
-
Kemeny, N.1
-
8
-
-
0036302615
-
Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: Results of a multivariate analysis of 3825 patients
-
Köhne CH, Cunningham D, Di Costanzo F, et al. Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 patients. Ann Oncol 2002;13:308-317
-
(2002)
Ann Oncol
, vol.13
, pp. 308-317
-
-
Köhne, C.H.1
Cunningham, D.2
Di Costanzo, F.3
-
9
-
-
0037080281
-
Comprehensive geritric assessment adds information to ECOG performance status in elderly cancer patients: An Italian Group for Geriatric Oncology Study
-
Repetto L, Fratino L, Audisio RA, et al. Comprehensive geritric assessment adds information to ECOG performance status in elderly cancer patients: an Italian Group for Geriatric Oncology Study. J Clin Oncol 2002; 20:494-502
-
(2002)
J Clin Oncol
, vol.20
, pp. 494-502
-
-
Repetto, L.1
Fratino, L.2
Audisio, R.A.3
-
10
-
-
68149165771
-
Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer
-
Souglakos J, Philips J, Wang R, et al. Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer. Br J Cancer 2009;101:465-472
-
(2009)
Br J Cancer
, vol.101
, pp. 465-472
-
-
Souglakos, J.1
Philips, J.2
Wang, R.3
-
11
-
-
0034712536
-
Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
-
Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000;355:1041-1047
-
(2000)
Lancet
, vol.355
, pp. 1041-1047
-
-
Douillard, J.Y.1
Cunningham, D.2
Roth, A.D.3
-
12
-
-
0034727063
-
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
-
Irinotecan Study Group
-
Saltz LB, Cox JV, Blanke C, et al. Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group. N Engl J Med 2000;343:905-914
-
(2000)
N Engl J Med
, vol.343
, pp. 905-914
-
-
Saltz, L.B.1
Cox, J.V.2
Blanke, C.3
-
13
-
-
24644432555
-
Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986
-
Kohne CH, van Cutsem E, Wils J, et al. Phase III study of weekly high-dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986. J Clin Oncol 2005;23:4856-4865
-
(2005)
J Clin Oncol
, vol.23
, pp. 4856-4865
-
-
Kohne, C.H.1
Van Cutsem, E.2
Wils, J.3
-
14
-
-
0033989203
-
Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer
-
Giacchetti S, Perpoint B, Zidani R, et al. Phase III multicenter randomized trial of oxaliplatin added to chronomodulated fluorouracil-leucovorin as first-line treatment of metastatic colorectal cancer. J Clin Oncol 2000;18:136-147
-
(2000)
J Clin Oncol
, vol.18
, pp. 136-147
-
-
Giacchetti, S.1
Perpoint, B.2
Zidani, R.3
-
15
-
-
0033874892
-
Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
-
de Gramont A, Figer A, Seymour M, et al. Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000;18:2938-2947
-
(2000)
J Clin Oncol
, vol.18
, pp. 2938-2947
-
-
De Gramont, A.1
Figer, A.2
Seymour, M.3
-
16
-
-
1842569206
-
A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
-
Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004;22:23-30
-
(2004)
J Clin Oncol
, vol.22
, pp. 23-30
-
-
Goldberg, R.M.1
Sargent, D.J.2
Morton, R.F.3
-
17
-
-
36048960109
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
-
Fuchs CS, Marshall J, Mitchell E, et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C study. J Clin Oncol 2007;25:4779-4786
-
(2007)
J Clin Oncol
, vol.25
, pp. 4779-4786
-
-
Fuchs, C.S.1
Marshall, J.2
Mitchell, E.3
-
18
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004;22:229-237
-
(2004)
J Clin Oncol
, vol.22
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
-
19
-
-
2142703727
-
Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment
-
Grothey A, Sargent D, Goldberg RM, et al. Survival of patients with advanced colorectal cancer improves with the availability of fluorouracil-leucovorin, irinotecan, and oxaliplatin in the course of treatment. J Clin Oncol 2004;22:1209-1214
-
(2004)
J Clin Oncol
, vol.22
, pp. 1209-1214
-
-
Grothey, A.1
Sargent, D.2
Goldberg, R.M.3
-
20
-
-
22844443043
-
Systemic therapy for metastatic colorectal cancer: Current options, current evidence
-
DOI 10.1200/JCO.2005.17.749
-
Kelly H, Goldberg RM. Systemic therapy for metastatic colorectal cancer: current options, current evidence. J Clin Oncol 2005;23:4553-4560 (Pubitemid 46196586)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.20
, pp. 4553-4560
-
-
Kelly, H.1
Goldberg, R.M.2
-
21
-
-
58049194302
-
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials
-
Arkenau HT, Arnold D, Cassidy J, et al. Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: a pooled analysis of randomized trials. J Clin Oncol 2008;26:5910-5917
-
(2008)
J Clin Oncol
, vol.26
, pp. 5910-5917
-
-
Arkenau, H.T.1
Arnold, D.2
Cassidy, J.3
-
22
-
-
43049126513
-
Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the irst-line treatment of patients with metastatic colorectal cancer. EORTC study 40015
-
Kohne CH, De Greve J, Hartmann JT, et al. Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. Ann Oncol 2008;19:920-926
-
(2008)
Ann Oncol
, vol.19
, pp. 920-926
-
-
Kohne, C.H.1
De Greve, J.2
Hartmann, J.T.3
-
23
-
-
34447277453
-
Sequential vs combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): A phase III randomised controlled trial
-
Koopman M, Antonini NF, Douma J, et al. Sequential vs combination chemotherapy with capecitabine, irinotecan, and oxaliplatin in advanced colorectal cancer (CAIRO): a phase III randomised controlled trial. Lancet 2007;370:135-142
-
(2007)
Lancet
, vol.370
, pp. 135-142
-
-
Koopman, M.1
Antonini, N.F.2
Douma, J.3
-
24
-
-
42949114492
-
Capecitabine and irinotecan as first-line treatment of advanced colorectal cancer
-
Punt CJA, Koopman M. Capecitabine and irinotecan as first-line treatment of advanced colorectal cancer. J Clin Oncol 2008;26:1907-1908
-
(2008)
J Clin Oncol
, vol.26
, pp. 1907-1908
-
-
Punt, C.J.A.1
Koopman, M.2
-
25
-
-
0032748608
-
Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance
-
Diasio RB, Johnson MR. Dihydropyrimidine dehydrogenase: its role in 5-fluorouracil clinical toxicity and tumor resistance. Clin Cancer Res 1999;5:2672-2673
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2672-2673
-
-
Diasio, R.B.1
Johnson, M.R.2
-
26
-
-
12244262239
-
Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency
-
van Kuilenburg AB, De Abreu RA, van Gennip AH. Pharmacogenetic and clinical aspects of dihydropyrimidine dehydrogenase deficiency. Ann Clin Biochem 2003;40:41-45
-
(2003)
Ann Clin Biochem
, vol.40
, pp. 41-45
-
-
Van Kuilenburg, A.B.1
De Abreu, R.A.2
Van Gennip, A.H.3
-
27
-
-
43749093441
-
Individual fluorouracil dose adjustment based on pharmacokinetic follow-up compared with conventional dosage: Results of a multicenter randomized trial of patients with metastatic colorectal cancer
-
Gamelin E, Delva R, Jacob J, et al. Individual fluorouracil dose adjustment based on pharmacokinetic follow-up compared with conventional dosage: results of a multicenter randomized trial of patients with metastatic colorectal cancer. J Clin Oncol 2008;26:2099-2105
-
(2008)
J Clin Oncol
, vol.26
, pp. 2099-2105
-
-
Gamelin, E.1
Delva, R.2
Jacob, J.3
-
28
-
-
43749115743
-
Will we ever be ready for blood level-guided therapy?
-
Walko CM, McLeod HL. Will we ever be ready for blood level-guided therapy? J Clin Oncol 2008;26:2078-2079
-
(2008)
J Clin Oncol
, vol.26
, pp. 2078-2079
-
-
Walko, C.M.1
McLeod, H.L.2
-
29
-
-
57449096129
-
Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741
-
Sanoff HK, Sargent DJ, Campbell ME, et al. Five-year data and prognostic factor analysis of oxaliplatin and irinotecan combinations for advanced colorectal cancer: N9741. J Clin Oncol 2008;26:5721-5727
-
(2008)
J Clin Oncol
, vol.26
, pp. 5721-5727
-
-
Sanoff, H.K.1
Sargent, D.J.2
Campbell, M.E.3
-
30
-
-
0012097766
-
Long term survivors (LTS) of metastatic colorectal cancer (MCRC) treated with chemotherapy only: A North Central Cancer Group (NCCTG) Review
-
[abstract 693]
-
Hobday T, Cha S, Sargent D, et al. Long term survivors (LTS) of metastatic colorectal cancer (MCRC) treated with chemotherapy only: a North Central Cancer Group (NCCTG) Review [abstract 693]. J Clin Oncol 2002;21(Suppl):174a
-
(2002)
J Clin Oncol
, vol.21
, Issue.SUPPL.
-
-
Hobday, T.1
Cha, S.2
Sargent, D.3
-
31
-
-
19944425122
-
First line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): Results of phase II study with a simplified biweekly schedule
-
Masi G, Allegrini G, Cupini S, et al. First line treatment of metastatic colorectal cancer with irinotecan, oxaliplatin and 5-fluorouracil/leucovorin (FOLFOXIRI): results of phase II study with a simplified biweekly schedule. Ann Oncol 2004;15:1766-1772
-
(2004)
Ann Oncol
, vol.15
, pp. 1766-1772
-
-
Masi, G.1
Allegrini, G.2
Cupini, S.3
-
32
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest
-
Falcone A, Ricci S, Brunetti I, et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: the Gruppo Oncologico Nord Ovest. J Clin Oncol 2007;25:1670-1676
-
(2007)
J Clin Oncol
, vol.25
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti, I.3
-
33
-
-
39149097520
-
Triplet combination of fluoropyrimidines, oxaliplatin, and irinotecan in the first-line treatment of metastatic colorectal cancer
-
Masi G, Vasile E, Loupakis F, et al. Triplet combination of fluoropyrimidines, oxaliplatin, and irinotecan in the first-line treatment of metastatic colorectal cancer. Clin Colorectal Cancer 2008;7:7-14
-
(2008)
Clin Colorectal Cancer
, vol.7
, pp. 7-14
-
-
Masi, G.1
Vasile, E.2
Loupakis, F.3
-
34
-
-
77956191560
-
FOLFOXIRI (irinotecan, oxaliplatin, infusional 5FU/LV) vs FOLFIRI as first-line treatment of metastatic colorectal cancer (mCRC): Updated results after 5 years follow up and risk-stratified analysis
-
Falcone A, Vasile E, Loupakis F, et al. FOLFOXIRI (irinotecan, oxaliplatin, infusional 5FU/LV) vs FOLFIRI as first-line treatment of metastatic colorectal cancer (mCRC): updated results after 5 years follow up and risk-stratified analysis. Ann Oncol 2009;20:Suppl 7:vii21
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 7
-
-
Falcone, A.1
Vasile, E.2
Loupakis, F.3
-
35
-
-
33748180303
-
First-line 5-fluorouracil/folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) does not impair the feasibility and the activity of second line treatments in metastatic colorectal cancer
-
Masi G, Marcucci L, Loupakis F, et al. First-line 5-fluorouracil/folinic acid, oxaliplatin and irinotecan (FOLFOXIRI) does not impair the feasibility and the activity of second line treatments in metastatic colorectal cancer. Ann Oncol 2006;17:1249-1254
-
(2006)
Ann Oncol
, vol.17
, pp. 1249-1254
-
-
Masi, G.1
Marcucci, L.2
Loupakis, F.3
-
36
-
-
61449180226
-
A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer
-
Fornaro L, Masi G, Bursi S, et al. A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer. Cancer Chemother Pharmacol 2009;63:965-969
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 965-969
-
-
Fornaro, L.1
Masi, G.2
Bursi, S.3
-
37
-
-
67349088298
-
A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer
-
Vasile E, Masi G, Fornaro L, et al. A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer. Br J Cancer 2009;100:1720-1724
-
(2009)
Br J Cancer
, vol.100
, pp. 1720-1724
-
-
Vasile, E.1
Masi, G.2
Fornaro, L.3
-
38
-
-
33645309877
-
FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): A multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG)
-
Souglakos J, Androulakis N, Syrigos K, et al. FOLFOXIRI (folinic acid, 5-fluorouracil, oxaliplatin and irinotecan) vs FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) as first-line treatment in metastatic colorectal cancer (MCC): a multicentre randomised phase III trial from the Hellenic Oncology Research Group (HORG). Br J Cancer 2006;94:798-805
-
(2006)
Br J Cancer
, vol.94
, pp. 798-805
-
-
Souglakos, J.1
Androulakis, N.2
Syrigos, K.3
-
39
-
-
34748918351
-
Survival and disease-progression benefits with treatment regimens for advanced colorectal cancer: a meta-analysis
-
DOI 10.1016/S1470-2045(07)70281-4, PII S1470204507702814
-
Golfinopoulos V, Salanti G, Pavlidis N, Ioannidis JPA. Survival and disease-progression benefi ts with treatment regimens for advanced colorectal cancer: a meta-analysis. Lancet Oncol 2007;8:898-911 (Pubitemid 47488054)
-
(2007)
Lancet Oncology
, vol.8
, Issue.10
, pp. 898-911
-
-
Golfinopoulos, V.1
Salanti, G.2
Pavlidis, N.3
Ioannidis, J.P.4
-
40
-
-
34447255724
-
Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): A randomised controlled trial
-
Seymour MT, Maughan TS, Ledermann JA, et al. Different strategies of sequential and combination chemotherapy for patients with poor prognosis advanced colorectal cancer (MRC FOCUS): a randomised controlled trial. Lancet 2007;370:143-152
-
(2007)
Lancet
, vol.370
, pp. 143-152
-
-
Seymour, M.T.1
Maughan, T.S.2
Ledermann, J.A.3
-
41
-
-
34447259379
-
Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard?
-
Schmoll HJ, Sargent D. Single agent fluorouracil for first-line treatment of advanced colorectal cancer as standard? Lancet 2007;370:105-107
-
(2007)
Lancet
, vol.370
, pp. 105-107
-
-
Schmoll, H.J.1
Sargent, D.2
-
42
-
-
60649088752
-
Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer
-
Cunningham D, Sirohi B, Pluzanska A, et al. Two different first-line 5-fluorouracil regimens with or without oxaliplatin in patients with metastatic colorectal cancer. Ann Oncol 2009;20:244-250
-
(2009)
Ann Oncol
, vol.20
, pp. 244-250
-
-
Cunningham, D.1
Sirohi, B.2
Pluzanska, A.3
-
43
-
-
43549084892
-
Capecitabine (Cap) and oxaliplatin (Ox) in elderly and/or frail patients with metastatic colorectal cancer: The FOCUS2 trial. ASCO Annual Meeting Proceedings Part I
-
Seymour MT, Maughan TS, Wasan HS, et al. Capecitabine (Cap) and oxaliplatin (Ox) in elderly and/or frail patients with metastatic colorectal cancer: the FOCUS2 trial. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2007;25(18S):9030
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 S
, pp. 9030
-
-
Seymour, M.T.1
Maughan, T.S.2
Wasan, H.S.3
-
44
-
-
33644843853
-
OPTIMOX1: A randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer: A GERCOR study
-
Tournigand C, Cervantes A, Figer A, et al. OPTIMOX1: a randomized study of FOLFOX4 or FOLFOX7 with oxaliplatin in a stop-and-go fashion in advanced colorectal cancer: a GERCOR study. J Clin Oncol 2006;24:394-400
-
(2006)
J Clin Oncol
, vol.24
, pp. 394-400
-
-
Tournigand, C.1
Cervantes, A.2
Figer, A.3
-
45
-
-
73349089651
-
Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? the GERCOR OPTIMOX2 study
-
[Epub ahead of print]
-
Chibaudel B, Maindrault-Goebel F, Lledo G, et al. Can chemotherapy be discontinued in unresectable metastatic colorectal cancer? The GERCOR OPTIMOX2 study. J Clin Oncol 2009. [Epub ahead of print]
-
(2009)
J Clin Oncol
-
-
Chibaudel, B.1
Maindrault-Goebel, F.2
Lledo, G.3
-
46
-
-
73349138901
-
Stop and go: Yes or no?
-
[Epub ahead of print]
-
Hochster HS. Stop and go: yes or no? J Clin Oncol 2009. [Epub ahead of print]
-
(2009)
J Clin Oncol
-
-
Hochster, H.S.1
-
47
-
-
33750925368
-
Italian Group for the Study of Digestive Tract Can. Alternating versus continuous 'FOLFIRI' in advanced colorectal cancer (ACC): A randomized 'GISCAD' trial. ASCO Annual Meeting Proceedings Part I
-
Labianca R, Floriani I, Cortesi E, et al. Italian Group for the Study of Digestive Tract Can. Alternating versus continuous 'FOLFIRI' in advanced colorectal cancer (ACC): a randomized 'GISCAD' trial. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2006;24(18S):3505
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 3505
-
-
Labianca, R.1
Floriani, I.2
Cortesi, E.3
-
48
-
-
43249095919
-
Tumor angiogenesis
-
Kerbel RS. Tumor angiogenesis. N Engl J Med 2008;358:2039-2049
-
(2008)
N Engl J Med
, vol.358
, pp. 2039-2049
-
-
Kerbel, R.S.1
-
49
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-2342
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
50
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, et al. Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J Clin Oncol 2005;23:3706-3712
-
(2005)
J Clin Oncol
, vol.23
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
-
51
-
-
39149108869
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Updated results rom the BICC-C study
-
Fuchs CS, Marshall J, Barrueco J. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: updated results from the BICC-C study. J Clin Oncol 2008;26:689-690
-
(2008)
J Clin Oncol
, vol.26
, pp. 689-690
-
-
Fuchs, C.S.1
Marshall, J.2
Barrueco, J.3
-
52
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E, et al. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26:2013-2019
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
-
53
-
-
72849128110
-
Bevacizumab (BV) in combination with FOLFOXIRI (irinotecan, oxaliplatin and infusional 5FU/LV) as first-line treatment of metastatic colorectal cancer (mCRC): A phase II study by the G.O.N.O. group
-
Masi G, Vasile E, Loupakis F, et al. Bevacizumab (BV) in combination with FOLFOXIRI (irinotecan, oxaliplatin and infusional 5FU/LV) as first-line treatment of metastatic colorectal cancer (mCRC): a phase II study by the G.O.N.O. group. Ann Oncol 2009;20:(Suppl 7):vii12
-
(2009)
Ann Oncol
, vol.20
, Issue.SUPPL. 7
-
-
Masi, G.1
Vasile, E.2
Loupakis, F.3
-
54
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ, et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: results from the Eastern Cooperative Oncology Group Study E3200. J Clin Oncol 2007;25:1539-1544
-
(2007)
J Clin Oncol
, vol.25
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
55
-
-
66149120036
-
Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: The BEAT study
-
Van Cutsem E, Rivera F, Berry S, et al. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study. Ann Oncol 2009;20:1842-1847
-
(2009)
Ann Oncol
, vol.20
, pp. 1842-1847
-
-
Van Cutsem, E.1
Rivera, F.2
Berry, S.3
-
56
-
-
33748999448
-
Safety of bevacizumab plus chemotherapy as first-line treatment of patients with metastatic colorectal cancer: Updated results from a large observational registry in the US (BRiTE). ASCO Annual Meeting Proceedings
-
Hedrick E, Kozloff M, Hainsworth J, et al. Safety of bevacizumab plus chemotherapy as first-line treatment of patients with metastatic colorectal cancer: updated results from a large observational registry in the US (BRiTE). ASCO Annual Meeting Proceedings. J Clin Oncol 2006;24(18S):3536
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 3536
-
-
Hedrick, E.1
Kozloff, M.2
Hainsworth, J.3
-
57
-
-
56749169353
-
Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: Results from a large observational cohort study (BRiTE)
-
Grothey A, Sugrue MM, Purdie DM, et al. Bevacizumab beyond first progression is associated with prolonged overall survival in metastatic colorectal cancer: results from a large observational cohort study (BRiTE). J Clin Oncol 2008;26:5326-5334
-
(2008)
J Clin Oncol
, vol.26
, pp. 5326-5334
-
-
Grothey, A.1
Sugrue, M.M.2
Purdie, D.M.3
-
58
-
-
63749114837
-
Hidden biases in an observational study of bevacizumab beyond progression
-
Kopetz S, Abbruzzese JL. Hidden biases in an observational study of bevacizumab beyond progression. J Clin Oncol 2009;27:1732-1733
-
(2009)
J Clin Oncol
, vol.27
, pp. 1732-1733
-
-
Kopetz, S.1
Abbruzzese, J.L.2
-
59
-
-
54949110541
-
Targeting EGFR in colorectal cancer
-
Messersmith WA, Ahnen DJ. Targeting EGFR in colorectal cancer. N Engl J Med 2008;359:1834-1836
-
(2008)
N Engl J Med
, vol.359
, pp. 1834-1836
-
-
Messersmith, W.A.1
Ahnen, D.J.2
-
60
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Erratum in: N Engl J Med 2009;360:1579
-
Ciardiello F, Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 2008;358:1160-74, Erratum in: N Engl J Med 2009;360:1579
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
61
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan refractory metastatic colorectal cancer. N Engl J Med 2004;351:337-345
-
(2004)
N Engl J Med
, vol.351
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
63
-
-
44249111440
-
EPIC: Phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer
-
Sobrero AF, Maurel J, Fehrenbacher L, et al. EPIC: phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:2311-2319
-
(2008)
J Clin Oncol
, vol.26
, pp. 2311-2319
-
-
Sobrero, A.F.1
Maurel, J.2
Fehrenbacher, L.3
-
64
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Kohne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med 2009;360:1408-1417
-
(2009)
N Engl J Med
, vol.360
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
-
65
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol 2009;27:663-671
-
(2009)
J Clin Oncol
, vol.27
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
66
-
-
24044500971
-
Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors
-
Segaert S, Van Cutsem E. Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors. Ann Oncol 2005;16:1425-1433
-
(2005)
Ann Oncol
, vol.16
, pp. 1425-1433
-
-
Segaert, S.1
Van Cutsem, E.2
-
67
-
-
34147103678
-
Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy- refractory metastatic colorectal cancer
-
Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007;25:1658-1664
-
(2007)
J Clin Oncol
, vol.25
, pp. 1658-1664
-
-
Van Cutsem, E.1
Peeters, M.2
Siena, S.3
-
68
-
-
63549110610
-
Six cases of treatment with panitumumab in patients with severe hypersensitivity reactions to cetuximab
-
Nielsen DL, Pfeiffer P, Jensen BV. Six cases of treatment with panitumumab in patients with severe hypersensitivity reactions to cetuximab. Ann Oncol 2009;20:798
-
(2009)
Ann Oncol
, vol.20
, pp. 798
-
-
Nielsen, D.L.1
Pfeiffer, P.2
Jensen, B.V.3
-
69
-
-
20144381957
-
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
-
Chung KY, Shia, J, et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 2005;23:1803-1810
-
(2005)
J Clin Oncol
, vol.23
, pp. 1803-1810
-
-
Chung, K.Y.1
Shia, J.2
-
70
-
-
33646228635
-
Kras mutation status is predictive of response to cetuximab therapy in colorectal cancer
-
Lievre A, Bachet JB, Le Corre D, et al. Kras mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res 2006;66:3992-3995
-
(2006)
Cancer Res
, vol.66
, pp. 3992-3995
-
-
Lievre, A.1
Bachet, J.B.2
Le Corre, D.3
-
71
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol 2008;26:1626-1634
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
72
-
-
65349084984
-
Kras status and efficacy in the Crystal study: 1-st line treatment of patients with metastatic colorectal cancer receiving FOLFIRI with or without cetuximab
-
Van Cutsem E, Lang I, D'Haens G, et al. Kras status and efficacy in the Crystal study: 1-st line treatment of patients with metastatic colorectal cancer receiving FOLFIRI with or without cetuximab. Ann Oncol 2008;19:viii44
-
(2008)
Ann Oncol
, vol.19
-
-
Van Cutsem, E.1
Lang, I.2
D'Haens, G.3
-
73
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 2008;359:1757-1765
-
(2008)
N Engl J Med
, vol.359
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
74
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy
-
Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti-epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol 2009;27:2091-2096
-
(2009)
J Clin Oncol
, vol.27
, pp. 2091-2096
-
-
Allegra, C.J.1
Jessup, J.M.2
Somerfield, M.R.3
-
75
-
-
70450195266
-
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC
-
Normanno N, Tejpar S, Morgillo F, et al. Implications for KRAS status and EGFR-targeted therapies in metastatic CRC. Nat Rev Clin Oncol 2009;6:519-527
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 519-527
-
-
Normanno, N.1
Tejpar, S.2
Morgillo, F.3
-
76
-
-
68749119351
-
KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
Loupakis F, Ruzzo A, Cremolini C, et al. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer 2009;101:715-721
-
(2009)
Br J Cancer
, vol.101
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
-
77
-
-
33646227448
-
Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy
-
Tonra JR, Deevi DS, Corcoran E, et al. Synergistic antitumor effects of combined epidermal growth factor receptor and vascular endothelial growth factor receptor-2 targeted therapy. Clin Cancer Res 2006;12(7 Pt 1):2197-2207
-
(2006)
Clin Cancer Res
, vol.12
, Issue.7 PART 1
, pp. 2197-2207
-
-
Tonra, J.R.1
Deevi, D.S.2
Corcoran, E.3
-
78
-
-
35648941728
-
Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan refractory colorectal cancer: The BOND-2 study
-
Saltz LB, Lenz HJ, Kindler HL, et al. Randomized phase II trial of cetuximab, bevacizumab, and irinotecan compared with cetuximab and bevacizumab alone in irinotecan refractory colorectal cancer: the BOND-2 study. J Clin Oncol 2007;25:4557-4561
-
(2007)
J Clin Oncol
, vol.25
, pp. 4557-4561
-
-
Saltz, L.B.1
Lenz, H.J.2
Kindler, H.L.3
-
79
-
-
59949102930
-
A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer
-
Hecht JR, Mitchell E, Chidiac T, et al. A randomized phase IIIB trial of chemotherapy, bevacizumab, and panitumumab compared with chemotherapy and bevacizumab alone for metastatic colorectal cancer. J Clin Oncol 2009;27:672-680
-
(2009)
J Clin Oncol
, vol.27
, pp. 672-680
-
-
Hecht, J.R.1
Mitchell, E.2
Chidiac, T.3
-
80
-
-
59749091477
-
Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
-
Tol J, Koopman M, Cats A, et al. Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 2009;360:563-572
-
(2009)
N Engl J Med
, vol.360
, pp. 563-572
-
-
Tol, J.1
Koopman, M.2
Cats, A.3
-
81
-
-
0032699922
-
Nonoperative management of primary colorectal cancer in patients with stage IV disease
-
Scoggins CR, Meszoely IM, Blanke CD, et al. Nonoperative management of primary colorectal cancer in patients with stage IV disease. Ann Surg Oncol 1999;6:651-657
-
(1999)
Ann Surg Oncol
, vol.6
, pp. 651-657
-
-
Scoggins, C.R.1
Meszoely, I.M.2
Blanke, C.D.3
-
82
-
-
36849074724
-
Safety and efficacy of first-line chemotherapy in unresected metastatic colorectal cancer
-
Puthillath A, Dunn KB, Rajput A, et al. Safety and efficacy of first-line chemotherapy in unresected metastatic colorectal cancer. Clin Colorectal Cancer 2007;6:710-715
-
(2007)
Clin Colorectal Cancer
, vol.6
, pp. 710-715
-
-
Puthillath, A.1
Dunn, K.B.2
Rajput, A.3
-
83
-
-
0345268703
-
Intestinal complications after chemotherapy for patients with unresected primary colorectal cancer and synchronous metastases
-
Tebbutt NC, Norman AR, Cunningham D, et al. Intestinal complications after chemotherapy for patients with unresected primary colorectal cancer and synchronous metastases. Gut 2003;52:568-573
-
(2003)
Gut
, vol.52
, pp. 568-573
-
-
Tebbutt, N.C.1
Norman, A.R.2
Cunningham, D.3
-
84
-
-
70249148634
-
Outcome of primary tumor in patients with synchronous stage IV colorectal cancer receiving combination chemotherapy without surgery as initial treatment
-
Poultsides GA, Servais EL, Saltz LB, et al. Outcome of primary tumor in patients with synchronous stage IV colorectal cancer receiving combination chemotherapy without surgery as initial treatment. J Clin Oncol 2009;27:3379-3384
-
(2009)
J Clin Oncol
, vol.27
, pp. 3379-3384
-
-
Poultsides, G.A.1
Servais, E.L.2
Saltz, L.B.3
-
85
-
-
4444325717
-
Use of surgery among elderly patients with stage IV colorectal cancer
-
Temple LK, Hsieh L, Wong WD, et al. Use of surgery among elderly patients with stage IV colorectal cancer. J Clin Oncol 2004;22:3475-3484
-
(2004)
J Clin Oncol
, vol.22
, pp. 3475-3484
-
-
Temple, L.K.1
Hsieh, L.2
Wong, W.D.3
-
86
-
-
54949108656
-
Management of patients with asymptomatic colorectal cancer and synchronous irresectable metastases
-
Scheer MGW, Sloots CEJ, van der Wilt GJ, Ruers TJM. Management of patients with asymptomatic colorectal cancer and synchronous irresectable metastases. Ann Oncol 2008;19:1829-1835
-
(2008)
Ann Oncol
, vol.19
, pp. 1829-1835
-
-
Scheer, M.G.W.1
Sloots, C.E.J.2
Van Der Wilt, G.J.3
Ruers, T.J.M.4
-
87
-
-
0038665606
-
Elective bowel resection for incurable stage IV colorectal cancer: Prognostic variables for asymptomatic patients
-
Ruo L, Gougoutas C, Paty PB, et al. Elective bowel resection for incurable stage IV colorectal cancer: prognostic variables for asymptomatic patients. J Am Coll Surg 2003;196:722-728
-
(2003)
J Am Coll Surg
, vol.196
, pp. 722-728
-
-
Ruo, L.1
Gougoutas, C.2
Paty, P.B.3
-
88
-
-
66149121478
-
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
-
Hapani S, Chu D, Wu S. Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol 2009;10:559-568
-
(2009)
Lancet Oncol
, vol.10
, pp. 559-568
-
-
Hapani, S.1
Chu, D.2
Wu, S.3
-
89
-
-
33750344419
-
Risk factors for gastrointestinal perforations in patients with metastatic colorectal cancer receiving bevacizumab plus chemotherapy. ASCO Annual Meeting Proceedings Part I
-
Sugrue M, Kozloff M, Hainsworth J, et al. Risk factors for gastrointestinal perforations in patients with metastatic colorectal cancer receiving bevacizumab plus chemotherapy. ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2006;24(18S):3535
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 3535
-
-
Sugrue, M.1
Kozloff, M.2
Hainsworth, J.3
-
90
-
-
66149147757
-
Initial Safety Report of NSABP C-08: A randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer
-
Allegra CJ, Yothers G, O'Connell MJ, et al. Initial Safety Report of NSABP C-08: a randomized phase III study of modified FOLFOX6 with or without bevacizumab for the adjuvant treatment of patients with stage II or III colon cancer. J Clin Oncol 2009;27:3385-3390
-
(2009)
J Clin Oncol
, vol.27
, pp. 3385-3390
-
-
Allegra, C.J.1
Yothers, G.2
O'Connell, M.J.3
-
91
-
-
77954426444
-
A Comparison of palliative stenting or emergent surgery for obstructing incurable colon cancer
-
[Epub ahead of print]
-
Vemulapalli R, Lara LF, Sreenarasimhaiah J, et al. A Comparison of palliative stenting or emergent surgery for obstructing incurable colon cancer. Dig Dis Sci 2009. [Epub ahead of print]
-
(2009)
Dig Dis Sci
-
-
Vemulapalli, R.1
Lara, L.F.2
Sreenarasimhaiah, J.3
-
92
-
-
34447528972
-
Stents for palliation of obstructive metastatic colon cancer impact on management and chemotherapy administration
-
Mehdi Karoui M, Charachon A, Delbaldo C, et al. Stents for palliation of obstructive metastatic colon cancer impact on management and chemotherapy administration. Arch Surg 2007;142:619-623
-
(2007)
Arch Surg
, vol.142
, pp. 619-623
-
-
Mehdi Karoui, M.1
Charachon, A.2
Delbaldo, C.3
-
93
-
-
66149117474
-
Bevacizumab-associated gastrointestinal perforation
-
Chau I, Cunningham D. Bevacizumab-associated gastrointestinal perforation. Lancet Oncol 2009;10:534-536
-
(2009)
Lancet Oncol
, vol.10
, pp. 534-536
-
-
Chau, I.1
Cunningham, D.2
-
94
-
-
34249894171
-
Gastrointestinal perforation due to bevacizumab in colorectal cancer
-
Saif MW, Elfiky A, Salem RR. Gastrointestinal perforation due to bevacizumab in colorectal cancer. Ann Surg Oncol 2007;14:1860-1869
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 1860-1869
-
-
Saif, M.W.1
Elfiky, A.2
Salem, R.R.3
-
95
-
-
58249088835
-
Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: Pooled analysis of cohorts of older patients from two randomized clinical trials
-
Kabbinavar FF, Hurwitz HI, Yi J, et al. Addition of bevacizumab to fluorouracil-based first-line treatment of metastatic colorectal cancer: pooled analysis of cohorts of older patients from two randomized clinical trials. J Clin Oncol 2009;27:199-205
-
(2009)
J Clin Oncol
, vol.27
, pp. 199-205
-
-
Kabbinavar, F.F.1
Hurwitz, H.I.2
Yi, J.3
-
96
-
-
34548141828
-
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
-
Scappaticci FA, Skillings JR, Holden SN, et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst 2007;99:1232-1239
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1232-1239
-
-
Scappaticci, F.A.1
Skillings, J.R.2
Holden, S.N.3
-
97
-
-
50649094504
-
Disparities in the use of chemotherapy and monoclonal antibody therapy for elderly advanced colorectal cancer patients in the community oncology setting
-
McKibbin T, Freib CR, Greene RE, et al. Disparities in the use of chemotherapy and monoclonal antibody therapy for elderly advanced colorectal cancer patients in the community oncology setting. Oncologist 2008;13:876-885
-
(2008)
Oncologist
, vol.13
, pp. 876-885
-
-
McKibbin, T.1
Freib, C.R.2
Greene, R.E.3
-
98
-
-
72849139789
-
How many colorectal cancer (CRC) patients older than 70 years may be safely treated with bevacizumab? ASCO Annual Meeting Proceedings Part I
-
Pasetto LM, Falci C, Sinigaglia G, et al. How many colorectal cancer (CRC) patients older than 70 years may be safely treated with bevacizumab? ASCO Annual Meeting Proceedings Part I. J Clin Oncol 2006;24(18S):13589
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
, pp. 13589
-
-
Pasetto, L.M.1
Falci, C.2
Sinigaglia, G.3
-
99
-
-
48749126163
-
Cetuximab efficacy and safety in a retrospective cohort of elderly patients with heavily pretreated metastatic colorectal cancer
-
Bouchahada M, Macarulla T, Spano JP, et al. Cetuximab efficacy and safety in a retrospective cohort of elderly patients with heavily pretreated metastatic colorectal cancer. Crit Rev Oncol Hematol 2008;67:255-262
-
(2008)
Crit Rev Oncol Hematol
, vol.67
, pp. 255-262
-
-
Bouchahada, M.1
MacArulla, T.2
Spano, J.P.3
-
100
-
-
33846705473
-
Single agent cetuximab as first-line treatment for elderly patients with advanced colorectal cancer. Preliminary results of a phase II study
-
abstract 324
-
Sastre J, Aranda E, Grávalos C, et al. Single agent cetuximab as first-line treatment for elderly patients with advanced colorectal cancer. Preliminary results of a phase II study. Ann Oncol 2006;17(Suppl 10):abstract 324
-
(2006)
Ann Oncol
, vol.17
, Issue.SUPPL. 10
-
-
Sastre, J.1
Aranda, E.2
Grávalos, C.3
-
101
-
-
72849144646
-
Cetuximab and capecitabine as first line treatment for elderly patients with metastatic colorectal cancer: Preliminary results of TTD trial
-
abstract 15027
-
Grávalos C, Rivers F, Massuti B, et al. Cetuximab and capecitabine as first line treatment for elderly patients with metastatic colorectal cancer: preliminary results of TTD trial. J Clin Oncol 2008;26(Suppl):abstract 15027
-
(2008)
J Clin Oncol
, vol.26
, Issue.SUPPL.
-
-
Grávalos, C.1
Rivers, F.2
Massuti, B.3
-
102
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D, et al. Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol 2008;9:962-972
-
(2008)
Lancet Oncol
, vol.9
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
-
103
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol 2008;26:5705-5712
-
(2008)
J Clin Oncol
, vol.26
, pp. 5705-5712
-
-
Di Nicolantonio, F.1
Martini, M.2
Molinari, F.3
-
104
-
-
61449202998
-
The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
-
Hurwitz HI, Yi J, Ince W, et al. The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer. Oncologist 2009;14:22-28
-
(2009)
Oncologist
, vol.14
, pp. 22-28
-
-
Hurwitz, H.I.1
Yi, J.2
Ince, W.3
-
105
-
-
53849098364
-
Sequential versus combination therapy in the treatment of patients with advanced colorectal cancer
-
Shah U, Goldberg RM. Sequential versus combination therapy in the treatment of patients with advanced colorectal cancer. Clin Colorectal Cancer 2008;7:315-320
-
(2008)
Clin Colorectal Cancer
, vol.7
, pp. 315-320
-
-
Shah, U.1
Goldberg, R.M.2
-
106
-
-
38349189743
-
Response-independent survival benefit in metastatic colorectal cancer: A comparative analysis of N9741 and AVF2107
-
Grothey A, Hedrick EE, Mass RD, et al. Response-independent survival benefit in metastatic colorectal cancer: a comparative analysis of N9741 and AVF2107. J Clin Oncol 2008;26:183-189
-
(2008)
J Clin Oncol
, vol.26
, pp. 183-189
-
-
Grothey, A.1
Hedrick, E.E.2
Mass, R.D.3
-
107
-
-
34548159466
-
Impact of complete response to chemotherapy on overall survival in advanced colorectal cancer: Results from Intergroup N9741
-
Dy GK, Krook JE, Green EM, et al. Impact of complete response to chemotherapy on overall survival in advanced colorectal cancer: results from Intergroup N9741. J Clin Oncol 2007;25:3469-3474
-
(2007)
J Clin Oncol
, vol.25
, pp. 3469-3474
-
-
Dy, G.K.1
Krook, J.E.2
Green, E.M.3
-
108
-
-
34548242294
-
Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer
-
DOI 10.1200/JCO.2006.10.4380
-
de Gramont A, Buyse M, Abrahantes JC, et al. Reintroduction of oxaliplatin is associated with improved survival in advanced colorectal cancer. J Clin Oncol 2007;25:3224-3229 (Pubitemid 47325605)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.22
, pp. 3224-3229
-
-
De Gramont, A.1
Buyse, M.2
Abrahantes, J.C.3
Burzykowski, T.4
Quinaux, E.5
Cervantes, A.6
Figer, A.7
Lledo, G.8
Flesch, M.9
Mineur, L.10
Carola, E.11
Etienne, P.-L.12
Rivera, F.13
Chirivella, I.14
Perez-Staub, N.15
Louvet, C.16
Andre, T.17
Tabah-Fisch, I.18
Tournigand, C.19
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