Detection of viral DNA in kidney graft preservation and washing solutions is predictive of posttransplant infections in pediatric recipients

Journal of Infectious Diseases

Volumn 200, Issue 9, 2009, Pages 1425-1433

  Barzon, Luisa ^a   Murer, Luisa ^a   Pacenti, Monia ^a   Biasolo, Maria Angela ^a   Della Vella, Manuela ^a   Ghirardo, Giulia ^a   Gamba, Pier Giorgio ^a   De Arias, Alejandro Espadas ^b   Zanon, Giovanni Franco ^a   Palú, Giorgio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

PRESERVATION SOLUTION; VIRUS DNA;

ADOLESCENT; ADULT; ARTICLE; BIOPSY TECHNIQUE; CHILD; CONTROLLED STUDY; CORRELATION ANALYSIS; EPSTEIN BARR VIRUS; FEMALE; GRAFT INFECTION; HOST CELL; HUMAN; HUMAN CYTOMEGALOVIRUS; HUMAN TISSUE; IMPLANTATION; INFANT; INFECTION RISK; KIDNEY GRAFT; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PARVOVIRUS; POLYOMA VIRUS; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; VIRUS DETECTION;

ADOLESCENT; ADULT; BK VIRUS; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS; DNA VIRUS INFECTIONS; DNA, VIRAL; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; INFANT; KAPLAN-MEIER ESTIMATE; KIDNEY TRANSPLANTATION; MALE; ORGAN PRESERVATION SOLUTIONS; PARVOVIRUS B19, HUMAN; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SEROLOGIC TESTS; YOUNG ADULT;

EID: 72849125459     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/644504     Document Type: Article

References (21)

1. Kotton CN, Fishman JA. Viral infection in the renal transplant recipient. J Am Soc Nephrol 2005; 16:1758-1774 (Pubitemid 41716482) (Pubitemid 41716482)
2. Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med 2007; 357:2601-2614
3. Barzon L, Murer L, Pacenti M, et al. Investigation of intrarenal viral infections in kidney transplant recipients unveils an association between parvovirus B19 and chronic allograft injury. J Infect Dis 2009; 199:372-380
4. Fishman JA, Strong DM, Kuehnert MJ. Organ and tissue safety workshop 2007: advances and challenges. Cell Tissue Bank 2009; 10:271-280
5. Fishman JA, Greewald MA, Kuehnert MK. Enhancing transplant safety: a new era in the microbiologic evaluation of organ donors? Am J Transplant 2007; 7:2652-2654
6. Ferraresso M, Ghio L, Zacchello G, et al. Pharmacokinetic of cyclosporine microemulsion in pediatric kidney recipients receiving a quadruple immunosuppressive regimen: the value of C2 blood levels. Transplantation 2005; 79:1164-1168 (Pubitemid 40664017) (Pubitemid 40664017)
7. Montini G, Murer L, Ghio L, et al. One-year results of basiliximab induction and tacrolimus associated with sequential steroid and MMF treatment in pediatric kidney transplant recipient. Transpl Int 2005; 18: 36-42. (Pubitemid 41742943) (Pubitemid 41742943)
8. Biasolo MA, Calistri A, Cesaro S, Gentile G, Mengoli C, Palú G. Case report: kinetics of Epstein-Barr virus load in a bone marrow transplant patient with no sign of lymphoproliferative disease. J Med Virol 2003; 69:220-224 (Pubitemid 36068878) (Pubitemid 36068878)
9. Mengoli C, Cusinato R, Biasolo MA, Cesaro S, Parolin C, Palú G. Assessment of CMV load in solid organ transplant recipients by pp65 antigenemia and real-time quantitative DNA PCR assay: correlation with pp67 RNA detection. J Med Virol 2004; 74:78-84. (Pubitemid 38988863) (Pubitemid 38988863)
10. 0. Cesaro S, Facchin C, Tridello G, et al. A prospective study of BK-virusassociated haemorrhagic cystitis in paediatric patients undergoing allogenic haematopoietic stem cell transplantation. Bone Marrow Transplant 2008; 41:363-370 (Pubitemid 351330731) (Pubitemid 351330731)
11. Potena L, Holweg CT, Vana ML, et al. Frequent occult infection with cytomegalovirus in cardiac transplant recipients despite antiviral prophylaxis. J Clin Microbiol 2007; 45:1804-1810 (Pubitemid 46933911) (Pubitemid 46933911)
12. Parsyan A, Candotti D. Human erythrovirus B19 and blood transfusion-an update. Transfus Med 2007; 17:263-278 (Pubitemid 47197759) (Pubitemid 47197759)
13. Murer L, Zacchello G, Bianchi D, et al. Thrombotic microangiopathy associated with parvovirus B 19 infection after renal transplantation. J Am Soc Nephrol 2000; 11:1132-1137 (Pubitemid 30367944)
14. Yango A Jr, Morrissey P, Gohh R, Wahbeh A. Donor-transmitted parvovirus infection in a kidney transplant recipient presenting as pancytopenia and allograft dysfunction. Transpl Infect Dis 2002; 4:163-166 (Pubitemid 35364782) (Pubitemid 35364782)
15. Kurtzman GJ, Cohen BJ, Field AM, Oseas R, Blaese RM, Young NS. Immune response to B19 parvovirus and an antibody defect in persistent viral infection. J Clin Invest 1989; 84:1114-1123 (Pubitemid 19247580)
16. Compston LI, Sarkobie F, Li C, Candotti D, Opare-Sem O, Allain JP. Multiplex real-time PCR for the detection and quantification of latent and persistent viral genomes in cellular or plasma blood fractions. J Virol Methods 2008; 151:47-54.
17. Nishiwaki M, FujimuroM, Teishikata Y, et al. Epidemiology of Epstein-Barr virus, cytomegalovirus, and Kaposis sarcoma-associated herpesvirus infections in peripheral blood leukocytes revealed by a multiplex PCR assay. J Med Virol 2006; 78:1635-1642 (Pubitemid 44672507) (Pubitemid 44672507)
18. Hirsch HH, Knowles W, Dickenmann M, et al. Prospective study of polyomavirus type BK replication and nephropathy in renal transplant recipients. N Engl J Med 2002; 347:488-496 (Pubitemid 34879336) (Pubitemid 34879336)
19. Fishman JA. BK virus nephropathy-polyomavirus adding insult to injury. N Engl J Med 2002; 347:527-530
20. Atencio IA, Shadan FF, Zhou XJ, Vaziri ND, Villarreal LP. Adult mouse kidneys become permissive to acute polyomavirus infection and reactivate persistent infections in response to cellular damage and regeneration. J Virol 1993; 67:1424-1432
21. Egli A, Infanti L, Dumoulin A, et al. Prevalence of polyomavirus BK and JC infection and replication in 400 healthy blood donors. J Infect Dis 2009; 199:837-84