Galanin potentiates supramaximal caerulein-stimulated pancreatic amylase secretion via its action on somatostatin secretion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 6, 2009, Pages

  Barreto, Savio G ^a   Carati, Colin J ^a   Schloithe, Ann C ^a   Toouli, James ^a   Saccone, Gino T P ^a  

^a FLINDERS UNIVERSITY   (Australia)

Author keywords

Cholinergic; Pancreatic exocrine secretion; Pancreatic lobules

Indexed keywords

AMYLASE; ATROPINE; CERULETIDE; DIAZOXIDE; GALANIN; SOMATOSTATIN; SOMATOSTATIN RECEPTOR; TETRODOTOXIN;

AMYLASE RELEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; NONHUMAN; PANCREAS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; PROTEIN SECRETION;

AMYLASES; ANIMALS; ATROPINE; CAERULEIN; DIAZOXIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; GALANIN; INSULIN; MICE; MUSCARINIC ANTAGONISTS; OCTREOTIDE; PANCREAS; RECEPTORS, GALANIN; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; SUBSTANCE P; TETRODOTOXIN;

EID: 72749111153     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00342.2009     Document Type: Article

References (46)

1. Ahren B, Andren-Sandberg A, Nilsson A. Galanin inhibits amylase secretion from isolated rat pancreatic acini. Pancreas 3: 559-562, 1988. (Pubitemid 19053247)
2. Ahren B. Autonomic regulation of islet hormone secretion - implications for health and disease. Diabetologia 43: 393-410, 2000. (Pubitemid 30237947)
3. Ahren B, Botthcher G, Kowalyk S, Dunning BE, Sundler F, Taborsky GJ Jr. Galanin is co-localised with noradrenaline and neuropeptide Y in dog pancreas and celiac ganglion. Cell Tissue Res 261: 49-58, 1990. (Pubitemid 20205950)
4. Amiranoff B, Lorinet AM, Laburthe M. Galanin inhibits somatostatin release by the rat islet cell tumour in culture, Rin-m. Eur J Pharmacol 191: 401-405, 1990.
5. Baltazar ET, Kitamura N, Hondo E. Galanin-like immunoreactive endocrine cells in bovine pancreas. J Anat 196, 285-291, 1999.
6. Barreto SG, Woods CM, Carati C, Schloithe AC, Jaya P, Toouli J, Saccone GTP. Galanin inhibits caerulein-stimulated pancreatic amylase secretion via cholinergic nerves and insulin. Am J Physiol Gastrointest Liver Physiol 297: G333-G339, 2009.
7. Bhandari M, Thomas AC, Carati CJ, Kawamoto M, Brooke-Smith ME, Toouli J, Saccone GTP. Galanin antagonism reduces hyperenzymemia associated with acute pancreatitis (AP) in a possum model. Gastroenterology 130: A707, 2006.
8. Bhandari M, Thomas AC, Carati CJ, Kawamoto M, Toouli J, Saccone GTP. Galanin antagonism ameliorates hyperenzymemia and pancreatic necrosis in caerulein-induced acute pancreatitis in the mouse. Pancreas. In press.
9. Boden G, Sivitz MC, Owen OE, Essa-Koumar N, Landor JH. Somatostatin suppresses secretin and pancreatic exocrine secretion. Science 190: 163-165, 1975.
10. Boyle MR, Verchere CB, McKnight G, Mathews S, Walker K, Taborsky G Jr. Canine galanin: sequence, expression and pancreatic effects. Regul Pept 50: 1-11, 1994. (Pubitemid 24046095)
11. Brooke-Smith ME, Carati CJ, Bhandari M, Toouli J, Saccone GT. Galanin in the regulation of pancreatic vascular perfusion. Pancreas 36: 267-273, 2008.
12. Bury R, Mashord MJ. Biological activity of C-terminal partial sequences of substance P. J Med Chem 19: 854-856, 1976.
13. Diaz-Carbiale Z, Parrado C, Vela C, Razani H, Covenas R, Fuxe K, Narvaez JA. Role of galanin and galanin (1-15) on cardiovascular control. Neuropeptides 39: 185-190, 2005. (Pubitemid 40804583)
14. Dunning BE, Taborsky GJ Jr. Galanin - sympathetic neurotransmitter in endocrine pancreas? Diabetes 37: 1157-1162, 1988.
15. Flowe KM, Lally KM, Mulholland MW. Galanin inhibits rat pancreatic amylase release via cholinergic suppression. Peptides 13: 487-492, 1992.
16. Fries JL, Murphy WA, Sueiras-Diaz J, Coy DH. Somatostatin antagonist analog increases GH, insulin, and glucagon release in the rat. Peptides 3: 811-814, 1982. (Pubitemid 13171622)
17. Garry DJ, Garry MG, Williams JA, Mahoney WC, Sorenson RL. Effects of islet hormones on amylase secretion and localization of somatostatin binding sites. Am J Physiol Gastrointest Liver Physiol 256: G897-G904, 1989.
18. Heintges T, Lüthen R, Niederau C. Inhibition of exocrine pancreatic secretion by somatostatin and its analogues. Digestion 55: 1-9, 1994. (Pubitemid 24020271)
19. Henderson JR. Why are the islets of Langerhans? Lancet 2: 469-470, 1969.
20. Herzig KH, Brunke G, Schon I, Schaffer M, Folsch UR. Mechanisms of galanin's inhibitory action on pancreatic enzyme secretion: modulation of cholinergic transmission-studies in vivo and in vitro. Gut 34: 1616-1621, 1993. (Pubitemid 23341859)
21. Ipp E, Dobbs RE, Arimura A, Vale W, Harris V, Unger RH. Release of immunoreactive somatostatin from the pancreas in response to glucose, amino acids, pancreaozymin-cholecystokinin and tolbutamide. J Clin Invest 60: 760-765, 1977. (Pubitemid 8180881)
22. Ipp E, Dobbs RE, Harris V, Arimura A, Vale W, Unger RH. The effects of gastrin, gastric inhibitory polypeptide, secretin, and the octapeptide of cholecystokinin upon immunoreactive somatostatin release by the perfused canine pancreas. J Clin Invest 60: 1216-1219, 1977. (Pubitemid 8223150)
23. Kinney GA, Emmerson PJ, Miller RJ. Galanin receptor-mediated inhibition of glutamate release in the arcuate nucleus of the hypothalamus. J Neurosci 18: 3489-3500, 1998. (Pubitemid 28225657)
24. Lee KY, Zhou L, Ren XS, Chang TM, Chey WY. An important role of endogenous insulin on exocrine pancreatic secretion in rats. Am J Physiol Gastrointest Liver Physiol 258: G268-G274, 1990. (Pubitemid 20095436)
25. Lee KY, Lee YL, Kim CD, Chang TM, Chey WY. Mechanism of action of insulin on pancreatic exocrine secretion in perfused rat pancreas. Am J Physiol Gastrointest Liver Physiol 267: G207-G212, 1994. (Pubitemid 2133171)
26. Li Y, Hao Y, Owyang C. High affinity CCK-A receptors on the vagus nerve mediate CCK-stimulated pancreatic secretion in rats. Am J Physiol Gastrointest Liver Physiol 273: G679-G685, 1997. (Pubitemid 27418788)
27. Lindskog S, Ahren B, Land T, Langel U, Bartfai T. The novel high-affinity antagonist, galantide, blocks the galanin-mediated inhibition of glucose-induced insulin secretion. Eur J Pharmacol 210: 183-188, 1992.
28. Louie DS, Chung OY. Carbachol acts through protein kinase C to modulate cholecystokinin receptors on pancreatic acini. Am J Physiol Gastrointest Liver Physiol 261: G981-G986, 1991.
29. Mantke R, Schubert D, Röcken C, Paege I, Halangk W, Peters B, Lippert H, Schulz HU. Caerulein or taurocholate induced enzymatic and histologic alterations in the isolated perfused rat pancreas. Langenbecks Arch Surg 394: 363-369, 2009.
30. Maouyo D, Morisset J. Amazing pancreas: specific regulation of pancreatic secretion of individual digestive enzymes in rats. Am J Physiol Endocrinol Metab 268: E349-E359, 1995.
31. Merritt AM, Kolts BE. Simultaneous pancreatic, gastric and hormonal responses to 2-deoxyglucose in the conscious pig. Q J Exp Physiol 68: 69-75, 1983.
32. Morisset J, Wong H, Walsh JH, Laine J, Bourassa J. Pancreatic CCK (B) receptors: their potential roles in somatostatin release and δ-cell proliferation. Am J Physiol Gastrointest Liver Physiol 279: G148-G156, 2000. (Pubitemid 30612693)
33. Ohnishi H, Mine T, Kojima I. Inhibition by somatostatin of amylase secretion induced by calcium and cyclic AMP in rat pancreatic acini. Biochem J 304: 531-536, 1994. (Pubitemid 24368234)
34. Owyang C. Physiological mechanisms of cholecystokinin action on pancreatic secretion. Am J Physiol Gastrointest Liver Physiol 271: G1-G7, 1996. (Pubitemid 26299719)
35. Park HS, Park IS, Lee YL, Kwon HY, Park HJ. Effects of intrapancreatic neuronal activation on cholecystokinin-induced exocrine secretion of isolated perfused rat pancreas. Pflügers Arch 437: 511-516, 1999.
36. Rhie DJ, Kim MJ, Choi WS, Lee KH, Sung JH, Min DS, Yoon SH, Hahn SJ, Kim MS, Jo YH. Effect of somatostatin on cholecystokinin-induced amylase release in rat pancreatic acini. Pancreas 23: 102-108, 2001.
37. Rouiller D, Schusdziarra V, Harris V, Unger RH. Release of pancreatic and gastric somatostatin-like immunoreactivity in response to the octapeptide of cholecystokinin, secretin gastric inhibitory polypeptide, and gastrin-17 in dogs. Endocrinology 107: 524-529, 1980. (Pubitemid 10040992)
38. Runzi M, Muller MK, Schmid P, von Schonfeld J, Goebell H. Stimulatory and inhibitory effects of galanin on exocrine and endocrine rat pancreas. Pancreas 13: 487-492, 1992.
39. Saillan-Barreau C, Clerc P, Adato M, Escrieut C, Vaysse N, Fourmy D, Dufresne M. Transgenic CCK-B/gastrin receptor mediates murine pancreatic exocrine secretion. Gastroenterology 115: 988-996, 1998. (Pubitemid 28452947)
40. Saluja AK, Saluja M, Printz H, Zavertnik A, Sengupta A, Steer ML. Experimental pancreatitis is mediated by low-affinity cholecystokinin receptors that inhibit digestive enzyme secretion. Proc Natl Acad Sci USA 86: 8968-8971, 1989. (Pubitemid 20010347)
41. Saluja A, Logsdon C, Garg P. Direct versus indirect action of cholecystokinin on human pancreatic acinar cells: Is it time for a judgment after a century of trial? Gastroenterology 135: 357-360, 2008.
42. Sankaran H, Goldfine I, Deveney CW, Wong KY, Williams JA. Binding of cholecystokinin to high affinity receptors on isolated rat pancreatic acini. J Biol Chem 255: 1849-1853, 1980.
43. Scheele G, Adler G, Kern H. Exocytosis occurs at the lateral plasma membrane of the pancreatic acinar cell during supramaximal secretagogues stimulation. Gastroenterology 92: 345-353, 1987. (Pubitemid 17231713)
44. Shah AU, Grant WM, Latif SU, Mannan ZM, Park AJ, Husain SZ. Cyclic AMP accelerates calcium waves in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol 294: G1328-G1334, 2008.
45. Tatemoto K, Rokaeus A, Jornvall H, McDonald TJ, Mutt V. Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett 164: 124-128, 1983. (Pubitemid 14201839)
46. Verspohl EJ, Ammon HP. Cholecystokinin (CCK8) regulates glucagon, insulin, and somatostatin secretion from isolated rat pancreatic islets: interaction with glucose. Pflügers Arch 410: 284-287, 1987.