Development and validation of a spectrofluorimetric method for the estimation of rivastigmine in formulations

Indian Journal of Pharmaceutical Sciences

Volumn 71, Issue 5, 2009, Pages 585-589

  Kapil, R ^a   Dhawan, S ^a   Singh, Bhupinder ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

Detection limit; Fluorescence spectrophotometry; Fluorimetry; Linearity; Quantitation limit; Validation

Indexed keywords

RIVASTIGMINE; WATER;

ACCURACY; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; COST EFFECTIVENESS ANALYSIS; DRUG FORMULATION; EXCITATION; FLUORESCENCE; PARAMETER; PRACTICE GUIDELINE; REPRODUCIBILITY; SPECTRAL SENSITIVITY; SPECTROFLUOROMETRY; VALIDATION PROCESS;

EID: 72749110960     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.58179     Document Type: Article

References (10)

1. Cummings J, Lefevre G, Small G, Appel-Dingemanse S. Pharmacokinetic rationale for the rivastigmine patch. Neurology 2007;69:S10-3.
2. Wilson B, Samanta MK, Santhi K, Kumar KP, Paramakrishnan N, Suresh B. Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain Res 2008;200:159-168
3. Vintiloiu A, Lafleur M, Bastiat G, Leroux JC. In situ-forming oleogel implant for rivastigmine delivery. Pharm Res 2008;25:845-852
4. Lefèvre G, Pommier F, Sedek G, Allison M, Huang HA, Kiese B, et al. Pharmacokinetics and bioavailability of the novel rivastigmine transdermal patch versus rivastigmine oral solution in healthy elderly subjects. J Clin Pharmacol 2008;48:246-252
5. Craparo EF, Pitarresi G, Bondi ML, Casaletto MP, Licciardi M, Giammona GA. Nanoparticulate drug-delivery system for rivastigmine: Physicochemical and in vitro biological characterization. Macromol Biosci 2007;8:247-259
6. Karthik A, Subramanian GS, Surulivelrajan M, Ranjithkumar A, Kamat SB. Fluorimetric determination of rivastigmine in rat plasma by a reverse phase high performance liquid chromatographic method: Application to a pharmacokinetic study. Arzneim Forsch 2008;58:205-210
7. The European agency for the evaluation of medical products. ICH Topic Q2B Note for guidance on validation of analytical procedures: Methodology. GPMP/ICH/ 281/95, 1996.
8. USP 27, NF 22. The United States Pharmacopeia and The National Formulary, Rockville, MD: The United States Pharmacopeial Convention; 20852, 2004. ISSN: 0195-7996, ISBN: 1-889788-20-0.
9. Huber L. Validation of analytical methods In: Validation and qualification in analytical laboratories, 2nd ed. New York: Informa Healthcare; 2007. p. 125-154
10. Venugopal K, Movva S, Saha RN. New, rapid, and sensitive spectrofluorimetric method for the estimation of gatifloxacin in bulk and formulations. Indian J Pharm Sci 2006;68:726.