Pharmaceutical tablet hardness measurements with THz pulsed imaging

34th International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2009

Volumn , Issue , 2009, Pages

  May, Robert K ^a   Han, Lianghao ^a   Alton, Jesse ^b   Zhong, Shuncong ^c   Elliott, James A ^a   Byers, Chris ^d   Gladden, Lynn F ^a   Evans, Mike ^b   Shen, Yaochun ^c   Zeitler, J Axel ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b TERAVIEW LTD   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d Oystar Manesty   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPRESSION FORCE; DENSITY DISTRIBUTIONS; DIAMETRIC COMPRESSION; FINITE ELEMENT ANALYSIS; HARDNESS MEASUREMENT; NON-DESTRUCTIVE MONITORING; PHARMACEUTICAL MANUFACTURING; PHARMACEUTICAL TABLETS; PULSED IMAGING; SOLID DOSAGE FORMS; SPATIAL DISTRIBUTION; STRONG CORRELATION; TERAHERTZ PULSED IMAGING;

COMPRESSION TESTING; HARDNESS; OPTICAL FREQUENCY CONVERSION;

EXPERIMENTS;

EID: 72749099610     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/ICIMW.2009.5325603     Document Type: Conference Paper

References (4)

1. L. Ho, R. Müller, K. C. Gordon, P. Kleinebudde, M. Pepper, T. Rades, Y. C. Shen, P. F. Taday, and J. A. Zeitler, "Terahertz pulsed imaging as an analytical tool for sustained-release tablet film coating," European Journal of Pharmaceutics and Biopharmaceutics, vol. 71, pp. 117-123, 2009.
2. M. Pore, J. A. Zeitler, S. Ngai, P. F. Taday, and C. L. Cooney, "Application of terahertz pulsed spectroscopy for evaluation of properties of pharmaceutical tablets," in Pittcon, The Pittsburgh Conference, Chicago, USA, 2007.
3. S.W. Hoag, V.S. Dave, V. Moolchandani, "Compression and Compaction" in Pharmaceutical Dosage Forms: Tablets, Vol. 1: Unit Operations and Mechanical Properties, L.L. Augsburger, S.W. Hoag, Eds., Informa Healthcare, 555-630, 2008.
4. L. H. Han, J. A. Elliott, A. C. Bentham, A. Mills, G. E. Amidon, and B. C. Hancock, "A modified Drucker-Prager cap model for die compaction simulation of pharmaceutical powders," International Journal of Solids and Structures, vol. 45, pp. 3088-3106, May 2008.