A validated capillary electrophoresis method to check for batch-to-batch consistency during recombinant human glycosylated interleukin-7 production campaigns

Journal of Pharmaceutical and Biomedical Analysis

Volumn 51, Issue 4, 2010, Pages 882-888

  Alahmad, Youssef ^a   Taverna, Myriam ^a   Mobdi, Hanane ^b   Duboeuf, Jérémy ^b   Grégoire, Anne ^b   Rancé, Iann ^b   Tran, Nguyet Thuy ^a  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b Cytheris   (France)

Author keywords

Capillary electrophoresis; Glycoprotein; Interleukin 7; Quality control; Validation

Indexed keywords

BORATE SODIUM; RECOMBINANT INTERLEUKIN 7; SODIUM HYDROXIDE;

ACCURACY; ANIMAL CELL; ARTICLE; CAPILLARY ZONE ELECTROPHORESIS; CHO CELL; CONTROLLED STUDY; DRUG SYNTHESIS; ELECTROPHORETIC MOBILITY; IONIC STRENGTH; NONHUMAN; PH; PRIORITY JOURNAL; QUALITY CONTROL; RELIABILITY; REPRODUCIBILITY; VALIDATION PROCESS;

ANIMALS; BUFFERS; CHO CELLS; CRICETINAE; CRICETULUS; DRUG STABILITY; ELECTROPHORESIS, CAPILLARY; ESCHERICHIA COLI; GLYCOSYLATION; HUMANS; HYDROGEN-ION CONCENTRATION; INTERLEUKIN-7; OBSERVER VARIATION; OSMOLAR CONCENTRATION; PROTEIN DENATURATION; PROTEIN STABILITY; QUALITY CONTROL; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 72549115617     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.09.013     Document Type: Article

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