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Volumn 25, Issue 11, 2009, Pages 2765-2775

Impact of fixed-dose and multi-pill combination dyslipidemia therapies on medication adherence and the economic burden of sub-optimal adherence

Author keywords

Adherence; Cardiovascular diseases; Cardiovascular events; Cholesterol; Dyslipidemia; Lipids; Managed care

Indexed keywords

LOVASTATIN PLUS NICOTINIC ACID; MEVINOLIN; SIMVASTATIN;

EID: 72549093882     PISSN: 03007995     EISSN: 14734877     Source Type: Journal    
DOI: 10.1185/03007990903297741     Document Type: Article
Times cited : (35)

References (49)
  • 1
    • 0038034509 scopus 로고    scopus 로고
    • Serum total cholesterol concentrations and awareness, treatment, and control of hypercholesterolemia among US adults: Findings from the national Health and Nutrition Examination Survey, 1999 to 2000
    • Ford ES, Mokdad AH, Giles WH, et al. Serum total cholesterol concentrations and awareness, treatment, and control of hypercholesterolemia among US adults: findings from the national Health and Nutrition Examination Survey, 1999 to 2000. Circulation 2003;107:2185-2189
    • (2003) Circulation , vol.107 , pp. 2185-2189
    • Ford, E.S.1    Mokdad, A.H.2    Giles, W.H.3
  • 2
    • 4444382796 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART Study): Case-control study
    • for the INTERHEART Study Investigators
    • Yusuf S, Hawken S, Ounpuu S, et al., for the INTERHEART Study Investigators. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART Study): case-control study. Lancet 2004;364:937-952
    • (2004) Lancet , vol.364 , pp. 937-952
    • Yusuf, S.1    Hawken, S.2    Ounpuu, S.3
  • 3
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults [final report]
    • Adult Treatment Panel III
    • Adult Treatment Panel III. Third report of the national cholesterol education program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults [final report]. Circulation 2002;106:3143-3421
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 4
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005;366:1267-1278
    • (2005) Lancet , vol.366 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 7
    • 33947217299 scopus 로고    scopus 로고
    • Achievement of optimal combined lipid values in a managed care setting: Is a new treatment paradigm needed?
    • Sarawate CA, Cziraky MJ, Stanek EJ, et al. Achievement of optimal combined lipid values in a managed care setting: is a new treatment paradigm needed? Clin Ther 2007;29:196-209
    • (2007) Clin Ther , vol.29 , pp. 196-209
    • Sarawate, C.A.1    Cziraky, M.J.2    Stanek, E.J.3
  • 8
    • 34547394233 scopus 로고    scopus 로고
    • The significance of low HDL-cholesterol levels in an ageing society at increased risk for cardiovascular disease
    • DOI 10.3132/dvdr.2007.032
    • Windler E, Schoffauer M, Zyriax B-C. The significance of low HDL-cholesterol levels in an ageing society at increased risk for cardiovascular disease. Diabetes Vasc Dis Res 2007;4:136-142 (Pubitemid 47167498)
    • (2007) Diabetes and Vascular Disease Research , vol.4 , Issue.2 , pp. 136-142
    • Windler, E.1    Schoffauer, M.2    Zyriax, B.-C.3
  • 9
    • 55049103596 scopus 로고    scopus 로고
    • Attainment of combined optimal lipid values and the impact of lipid medication on cardiovascular outcomes and costs in a commercially insured population in the US
    • Quimbo RA, Simko RJ, Cziraky MJ, et al. Attainment of combined optimal lipid values and the impact of lipid medication on cardiovascular outcomes and costs in a commercially insured population in the US. J Med Econ 2008;11:449-470
    • (2008) J Med Econ , vol.11 , pp. 449-470
    • Quimbo, R.A.1    Simko, R.J.2    Cziraky, M.J.3
  • 10
    • 33644849222 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2006 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Thom T, Haase N, Rosamond W, et al. Heart disease and stroke statistics - 2006 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2006;113:e85-151
    • (2006) Circulation , vol.113
    • Thom, T.1    Haase, N.2    Rosamond, W.3
  • 11
    • 41549145797 scopus 로고    scopus 로고
    • Comparison of drug adherence rates among patients with seven different medical conditions
    • Briesacher BA, Andrade SE, Fouayzi H, et al. Comparison of drug adherence rates among patients with seven different medical conditions. Pharmacotherapy 2008;28:437-443
    • (2008) Pharmacotherapy , vol.28 , pp. 437-443
    • Briesacher, B.A.1    Andrade, S.E.2    Fouayzi, H.3
  • 12
    • 40949131340 scopus 로고    scopus 로고
    • Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease
    • Ho PM, Magid DJ, Shetterly SM, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J 2008;155:772-779
    • (2008) Am Heart J , vol.155 , pp. 772-779
    • Ho, P.M.1    Magid, D.J.2    Shetterly, S.M.3
  • 13
    • 34548642425 scopus 로고    scopus 로고
    • Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: The heart and soul study
    • DOI 10.1001/archinte.167.16.1798
    • Gehi AK, Ali S, Na B, et al. Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study. Arch Intern Med 2007;167:1798-1803 (Pubitemid 47403069)
    • (2007) Archives of Internal Medicine , vol.167 , Issue.16 , pp. 1798-1803
    • Gehi, A.K.1    Ali, S.2    Na, B.3    Whooley, M.A.4
  • 15
    • 3042617444 scopus 로고    scopus 로고
    • Suboptimal statin adherence and discontinuation in primary and secondary prevention populations. Should we target patients with the most to gain?
    • Ellis JJ, Erickson SR, Stevenson JG, et al. Suboptimal statin adherence and discontinuation in primary and secondary prevention populations. Should we target patients with the most to gain? J Gen Intern Med 2004;19:638-645
    • (2004) J Gen Intern Med , vol.19 , pp. 638-645
    • Ellis, J.J.1    Erickson, S.R.2    Stevenson, J.G.3
  • 16
    • 0032513736 scopus 로고    scopus 로고
    • Persistence of use of lipid-lowering medications. A cross-national study
    • Avorn J, Monette J, Lacour A, et al. Persistence of use of lipid-lowering medications. A cross-national study. JAMA 1998;279:1458-1462
    • (1998) JAMA , vol.279 , pp. 1458-1462
    • Avorn, J.1    Monette, J.2    Lacour, A.3
  • 18
    • 18444412930 scopus 로고    scopus 로고
    • Determinants of compliance with statin therapy and low-density lipoprotein cholesterol goal attainment in a managed care population
    • Schultz JS, O'Donnell JC, McDonough KL, et al. Determinants of compliance with statin therapy and low-density lipoprotein cholesterol goal attainment in a managed care population. Am J Manag Care 2005;11:306-312
    • (2005) Am J Manag Care , vol.11 , pp. 306-312
    • Schultz, J.S.1    O'Donnell, J.C.2    McDonough, K.L.3
  • 20
    • 38049053496 scopus 로고    scopus 로고
    • Association between copayment and adherence to statin treatment initiated after coronary heart disease hospitalization: A longitudinal, retrospective, cohort study
    • Ye X, Gross CR, Schommer J, et al. Association between copayment and adherence to statin treatment initiated after coronary heart disease hospitalization: a longitudinal, retrospective, cohort study. Clin Ther 2007;29:2748-2757
    • (2007) Clin Ther , vol.29 , pp. 2748-2757
    • Ye, X.1    Gross, C.R.2    Schommer, J.3
  • 21
    • 37849051687 scopus 로고    scopus 로고
    • Impact of prescription size on statin adherence and cholesterol levels
    • Batal HA, Krantz MJ, Dale RA, et al. Impact of prescription size on statin adherence and cholesterol levels. BMC Health Serv Res 2007;7:175
    • (2007) BMC Health Serv Res , vol.7 , pp. 175
    • Batal, H.A.1    Krantz, M.J.2    Dale, R.A.3
  • 22
    • 13244279642 scopus 로고    scopus 로고
    • Pharmacoeconomic impact of non-compliance with statins
    • Peterson AM, McGhan WF. Pharmacoeconomic impact of non-compliance with statins. Pharmacoeconomics 2005;23:13-25
    • (2005) Pharmacoeconomics , vol.23 , pp. 13-25
    • Peterson, A.M.1    McGhan, W.F.2
  • 23
    • 56849102407 scopus 로고    scopus 로고
    • Improved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy
    • Patel BV, Remigio-Baker RA, Thiebauld P, et al. Improved persistence and adherence to diuretic fixed-dose combination therapy compared to diuretic monotherapy. BMC Fam Pract 2008;9:61
    • (2008) BMC Fam Pract , vol.9 , pp. 61
    • Patel, B.V.1    Remigio-Baker, R.A.2    Thiebauld, P.3
  • 25
    • 42449099867 scopus 로고    scopus 로고
    • Impact of fixed-dose combination drugs on adherence to prescription medications
    • Pan F, Chernew ME, Fendrick AM. Impact of fixed-dose combination drugs on adherence to prescription medications. J Gen Intern Med 2008;23:611-614
    • (2008) J Gen Intern Med , vol.23 , pp. 611-614
    • Pan, F.1    Chernew, M.E.2    Fendrick, A.M.3
  • 26
    • 34547636649 scopus 로고    scopus 로고
    • Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents
    • DOI 10.2146/ajhp060434
    • Gerbino PP, Shoheiber O. Adherence patterns among patients treated with fixed-dose combination versus separate antihypertensive agents. Am J Health Syst Pharm 2007;64:1279-1283 (Pubitemid 47216196)
    • (2007) American Journal of Health-System Pharmacy , vol.64 , Issue.12 , pp. 1279-1283
    • Gerbino, P.P.1    Shoheiber, O.2
  • 27
    • 34250179723 scopus 로고    scopus 로고
    • Fixed-Dose Combinations Improve Medication Compliance: A Meta-Analysis
    • DOI 10.1016/j.amjmed.2006.08.033, PII S000293430601151X
    • Bangalore S, Kamalakkannan G, Parkar S, et al. Fixed-dose combinations improve medication compliance: a meta-analysis. Am J Med 2007;120:713-719 (Pubitemid 47176510)
    • (2007) American Journal of Medicine , vol.120 , Issue.8 , pp. 713-719
    • Bangalore, S.1    Kamalakkannan, G.2    Parkar, S.3    Messerli, F.H.4
  • 28
    • 0035353085 scopus 로고    scopus 로고
    • Improving compliance in your dyslipidemia patient: An evidence-based approach
    • Becker DM, Allen JK. Improving compliance in your dyslipidemia patient: an evidence-based approach. J Am Acad Nurse Pract 2001;13:200-207
    • (2001) J Am Acad Nurse Pract , vol.13 , pp. 200-207
    • Becker, D.M.1    Allen, J.K.2
  • 29
    • 51249091910 scopus 로고    scopus 로고
    • Patient adherence in COPD
    • Bourbeau J, Bartlett SJ. Patient adherence in COPD. Thorax 2008;63:831-838
    • (2008) Thorax , vol.63 , pp. 831-838
    • Bourbeau, J.1    Bartlett, S.J.2
  • 30
    • 0035111495 scopus 로고    scopus 로고
    • Polypharmacy and medication adherence: Small steps on a long road
    • Murray MD, Kroenke K. Polypharmacy and medication adherence: small steps on a long road. J Gen Intern Med 2001;16:137-139 (Pubitemid 32183574)
    • (2001) Journal of General Internal Medicine , vol.16 , Issue.2 , pp. 137-139
    • Murray, M.D.1    Kroenke, K.2
  • 31
    • 40949125165 scopus 로고    scopus 로고
    • Polypharmacy in the elderly: Maximizing benefit, minimizing harm
    • Ballentine NH. Polypharmacy in the elderly: maximizing benefit, minimizing harm. Crit Care Nurs Q 2008;31:40-45
    • (2008) Crit Care Nurs Q , vol.31 , pp. 40-45
    • Ballentine, N.H.1
  • 32
    • 4043082845 scopus 로고    scopus 로고
    • Extended-release niacin/lovastatin: The first combination product for dyslipidemia
    • Bays HE. Extended-release niacin/lovastatin: the first combination product for dyslipidemia. Expert Rev Cardiovasc Ther 2004;2:485-501
    • (2004) Expert Rev Cardiovasc Ther , vol.2 , pp. 485-501
    • Bays, H.E.1
  • 33
    • 33746948861 scopus 로고    scopus 로고
    • Adherence and persistence with single-dosage form extended-release niacin/lovastatin compared with statins alone or in combination with extended-release niacin
    • DOI 10.1345/aph.1G646
    • LaFleur J, Thompson CJ, Joish VN, et al. Adherence and persistence with single-dosage form niacin extended-release/lovastatin compared with statin alone or in combination with niacin extended-release. Ann Pharmacother 2006;40:1274-1279 (Pubitemid 44204956)
    • (2006) Annals of Pharmacotherapy , vol.40 , Issue.7-8 , pp. 1274-1279
    • Lafleur, J.1    Thompson, C.J.2    Joish, V.N.3    Charland, S.L.4    Oderda, G.M.5    Brixner, D.I.6
  • 34
    • 22544468809 scopus 로고    scopus 로고
    • Estimating medication persistency using administrative claims data
    • Sikka R, Xia F, Aubert RE. Estimating medication persistency using administrative claims data. Am J Manag Care 2005;11:449-457 (Pubitemid 41022729)
    • (2005) American Journal of Managed Care , vol.11 , Issue.7 , pp. 449-457
    • Sikka, R.1    Xia, F.2    Aubert, R.E.3
  • 35
    • 33845870422 scopus 로고    scopus 로고
    • Antihypertensive Medication Adherence in the Department of Veterans Affairs
    • DOI 10.1016/j.amjmed.2006.06.028, PII S0002934306007765
    • Siegel D, Lopez J, Meier J. Antihypertensive medication adherence in the Department of Veteran Affairs. Am J Med 2007;120:26-32 (Pubitemid 46026987)
    • (2007) American Journal of Medicine , vol.120 , Issue.1 , pp. 26-32
    • Siegel, D.1    Lopez, J.2    Meier, J.3
  • 36
    • 33751566656 scopus 로고    scopus 로고
    • Medication adherence and the associated health-economic impact among patients with type 2 diabetes mellitus converting to insulin pen therapy: An analysis of third-party managed care claims data
    • DOI 10.1016/j.clinthera.2006.10.004, PII S014929180600244X
    • Lee WC, Balu S, Cobden D, et al. Medication adherence and the associated health-economic impact among patients with type 2 diabetes mellitus converting to insulin pen therapy: an analysis of third-party managed care claims data. Clin Ther 2006;28:1712-1725 (Pubitemid 44841979)
    • (2006) Clinical Therapeutics , vol.28 , Issue.10 , pp. 1712-1725
    • Lee, W.C.1    Balu, S.2    Cobden, D.3    Joshi, A.V.4    Pashos, C.L.5
  • 37
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
    • DOI 10.1016/0021-9681(87)90171-8
    • Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-383 (Pubitemid 17055592)
    • (1987) Journal of Chronic Diseases , vol.40 , Issue.5 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.A.3    MacKenzie, C.R.4
  • 38
    • 0026639706 scopus 로고
    • Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases
    • Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 1992;45:613-619
    • (1992) J Clin Epidemiol , vol.45 , pp. 613-619
    • Deyo, R.A.1    Cherkin, D.C.2    Ciol, M.A.3
  • 39
    • 36248929314 scopus 로고    scopus 로고
    • Medication taking and diabetes: A systematic review of the literature
    • Odegard PS, Capoccia K. Medication taking and diabetes: a systematic review of the literature. Diabetes Educ 2007;33:1014-1029
    • (2007) Diabetes Educ , vol.33 , pp. 1014-1029
    • Odegard, P.S.1    Capoccia, K.2
  • 42
    • 21044451014 scopus 로고    scopus 로고
    • Medication adherence trends with statins
    • Huser MA, Evans TS, Berger V. Medication adherence trends with statins. Adv Ther 2005;22:163-171
    • (2005) Adv Ther , vol.22 , pp. 163-171
    • Huser, M.A.1    Evans, T.S.2    Berger, V.3
  • 43
    • 37349082807 scopus 로고    scopus 로고
    • The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: A review
    • DOI 10.1111/j.1742-1241.2007.01630.x
    • Cramer JA, Benedict A, Muszbek N, et al. The significance of compliance and persistence in the treatment of diabetes, hypertension and dyslipidaemia: a review. Int J Clin Pract 2008;62:76-87 (Pubitemid 350294021)
    • (2008) International Journal of Clinical Practice , vol.62 , Issue.1 , pp. 76-87
    • Cramer, J.A.1    Benedict, A.2    Muszbek, N.3    Keskinaslan, A.4    Khan, Z.M.5
  • 44
    • 60549097683 scopus 로고    scopus 로고
    • Impact of a prescription copayment increase on lipid-lowering medication adherence in veterans
    • Doshi JA, Zhu J, Lee BY, et al. Impact of a prescription copayment increase on lipid-lowering medication adherence in veterans. Circulation 2009;119:390-397
    • (2009) Circulation , vol.119 , pp. 390-397
    • Doshi, J.A.1    Zhu, J.2    Lee, B.Y.3
  • 45
    • 14844350047 scopus 로고    scopus 로고
    • Adherence to a fixed-dose combination of rosiglitazone maleate/metformin hydrochloride in subjects with type 2 diabetes mellitus: A retrospective database analysis
    • DOI 10.1016/j.clinthera.2004.12.018
    • Vanderpoel DR, Hussein MA, Watson-Heidari T, et al. Adherence to a fixed-dose combination of rosiglitazone maleate/metformin hydrochloride in subjects with type 2 diabetes mellitus: a retrospective database analysis. Clin Ther 2004;26:2066-2075 (Pubitemid 40353616)
    • (2004) Clinical Therapeutics , vol.26 , Issue.12 , pp. 2066-2075
    • Vanderpoel, D.R.1    Hussein, M.A.2    Watson-Heidari, T.3    Perry, A.4
  • 46
    • 20544460816 scopus 로고    scopus 로고
    • Impact of medication adherence on hospitalization risk and healthcare cost
    • Sokol MC, McGuigan KA, Verbrugge RR, et al. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care 2005;43:521-530
    • (2005) Med Care , vol.43 , pp. 521-530
    • Sokol, M.C.1    McGuigan, K.A.2    Verbrugge, R.R.3
  • 47
    • 65349142462 scopus 로고    scopus 로고
    • Increased persistency in medication use by U.S. Medicare beneficiaries with diabetes is associated with lower hospitalization rates and cost savings
    • Stuart BC, Simoni-Wastila L, Zhao L, et al. Increased persistency in medication use by U.S. Medicare beneficiaries with diabetes is associated with lower hospitalization rates and cost savings. Diabetes Care 2009;32:647-649
    • (2009) Diabetes Care , vol.32 , pp. 647-649
    • Stuart, B.C.1    Simoni-Wastila, L.2    Zhao, L.3
  • 48
    • 1542724790 scopus 로고    scopus 로고
    • Costs and utilization associated with pharmaceutical adherence in a diabetic population
    • Hepke KL, Martus MT, Share DA. Costs and utilization associated with pharmaceutical adherence in a diabetic population. Am J Manag Care 2004;10:144-151
    • (2004) Am J Manag Care , vol.10 , pp. 144-151
    • Hepke, K.L.1    Martus, M.T.2    Share, D.A.3
  • 49
    • 0346243856 scopus 로고    scopus 로고
    • Varying Cost and Free Nicotinic Acid Content in over-the-Counter Niacin Preparations for Dyslipidemia
    • Meyers CD, Carr MC, Park S, et al. Varying cost and free nicotinic acid content in over-the-counter niacin preparations for dyslipidemia. Ann Intern Med 2003;139:996-1002 (Pubitemid 37523064)
    • (2003) Annals of Internal Medicine , vol.139 , Issue.12 , pp. 996-1002
    • Meyers, C.D.1    Carr, M.C.2    Park, S.3    Brunzell, J.D.4


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