The use of cimetidine to reduce dapsone-dependent haematological side-effects in a patient with mucous membrane pemphigoid

Clinical and Experimental Dermatology

Volumn 34, Issue 8, 2009, Pages

  Goolamali, S I ^a   MacFarlane, C S ^a  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CIMETIDINE; DAPSONE; MINOCYCLINE; PREDNISOLONE; STEROID;

AGED; BEDTIME DOSAGE; BLOOD ANALYSIS; CASE REPORT; DRUG EFFICACY; HEMOLYTIC ANEMIA; HISTOPATHOLOGY; HUMAN; LETTER; MALE; MORNING DOSAGE; MUCOUS MEMBRANE PEMPHIGOID; PRIORITY JOURNAL;

AGED; ANEMIA, HEMOLYTIC; CIMETIDINE; DAPSONE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MALE; PEMPHIGOID, BENIGN MUCOUS MEMBRANE;

EID: 72549085252     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2009.03710.x     Document Type: Letter

References (6)

1. Coleman MD. Dapsone. modes of action, toxicity and possible strategies for increasing patient tolerance. Br J Dermatol 1993 129 : 507 513.
2. Booth SA, Moody CE, Dahl MV et al. Dapsone suppresses integrin-mediated neutrophil adherence function. J Invest Dermatol 1992 98 : 135 140.
3. Coleman MD, Scott AK, Breckenridge AM et al. The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man. Br J Clin Pharmacol 1990 30 : 761 767.
4. Coleman MD, Rhodes LE, Scott AK et al. The use of cimetidine to reduce dapsone-dependent methaemoglobinaemia in dermatitis herpetiformis patients. Br J Clin Pharmacol 1992 34 : 244 249.
5. Rhodes LE, Tingle MD, Park BK et al. Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy. Br J Dermatol 1995 132 : 257 262.
6. Prussick R, Ali MA, Rosenthal D et al. The protective effect of Vitamin E on the hemolysis associated with dapsone treatment in patients with dermatitis herpetiformis. Arch Dermatol 1992 128 : 210 213.