ANIMALS;
CONFIDENCE INTERVALS;
DATA INTERPRETATION, STATISTICAL;
DISEASE MODELS, ANIMAL;
DRUG EVALUATION, PRECLINICAL;
META-ANALYSIS AS TOPIC;
MICE;
NEUROPROTECTIVE AGENTS;
OUTCOME ASSESSMENT (HEALTH CARE);
PREDICTIVE VALUE OF TESTS;
RATS;
RESEARCH DESIGN;
STROKE;
Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions
Gladstone D.J., Black S.E., and Hakim A.M. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 33 (2002) 2123-2136
A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke
Savitz S.I. A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke. Exp Neurol 205 (2007) 20-25
Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality
Macleod M.R., van der Worp H.B., Sena E.S., et al. Evidence for the efficacy of NXY-059 in experimental focal cerebral ischaemia is confounded by study quality. Stroke 39 (2008) 2824-2829
Sample size calculations in acute stroke trials: a systematic review of their reporting, characteristics, and relationship with outcome
Weaver C.S., Leonardi-Bee J., Bath-Hextall F.J., et al. Sample size calculations in acute stroke trials: a systematic review of their reporting, characteristics, and relationship with outcome. Stroke 35 (2004) 1216-1224
Comparison of two variance-estimation methods for a standardized economic processing system
American Statistical Association;
Tremblay A, Sigman RS. Comparison of two variance-estimation methods for a standardized economic processing system. Proceedings of the survey research methods section. American Statistical Association; 1996. p. 204-8.
Acute stroke therapy by inhibition of neutrophils (astin): an adaptive dose-response study of UK-279, 276 in acute ischemic stroke
Krams M., Lees K.R., Hacke W., et al. Acute stroke therapy by inhibition of neutrophils (astin): an adaptive dose-response study of UK-279, 276 in acute ischemic stroke. Stroke 34 (2003) 2543-2548
NXY-059 for the treatment of acute stroke: Pooled analysis of the SAINT I and II trials
Diener H.-C., Lees K.R., Lyden P., et al. NXY-059 for the treatment of acute stroke: Pooled analysis of the SAINT I and II trials. Stroke 39 (2008) 1751-1758