Plasma hyperosmolality elevates the internal temperature threshold for active thermoregulatory vasodilation during heat stress in humans

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 6, 2009, Pages

  Shibasaki, Manabu ^a   Aoki, Ken ^b   Morimoto, Keiko ^a   Johnson, John M ^c   Takamata, Akira ^a  

^a NARA WOMEN'S UNIVERSITY   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Body fluid; Osmoregulation; Skin blood flow; Sweating; Thermoregulation

Indexed keywords

AMMONIUM CHLORIDE; BRETYLIUM TOSYLATE; GLUCOSE; SODIUM CHLORIDE;

ADULT; ARTICLE; BODY FLUID; CLINICAL ARTICLE; COLD STRESS; CONTROLLED STUDY; HEAT STRESS; HUMAN; HUMAN EXPERIMENT; HUMIDITY; HYPEROSMOLALITY; LASER DOPPLER FLOWMETRY; MALE; OSMOREGULATION; PRIORITY JOURNAL; ROOM TEMPERATURE; SKIN BLOOD FLOW; SKIN TEMPERATURE; SWEATING; THERMOREGULATION; VASODILATATION;

ADMINISTRATION, CUTANEOUS; ADRENERGIC ANTAGONISTS; BLOOD FLOW VELOCITY; BODY TEMPERATURE REGULATION; BRETYLIUM TOSYLATE; HEART RATE; HEAT STRESS DISORDERS; HUMANS; IMMERSION; INFUSIONS, INTRAVENOUS; IONTOPHORESIS; ISOTONIC SOLUTIONS; LASER-DOPPLER FLOWMETRY; MALE; OSMOLAR CONCENTRATION; REGIONAL BLOOD FLOW; SALINE SOLUTION, HYPERTONIC; SENSORY THRESHOLDS; SKIN; SODIUM CHLORIDE; TIME FACTORS; VASODILATION; YOUNG ADULT;

EID: 72449209676     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00242.2009     Document Type: Article

References (38)

1. Aoki K, Stephens DP, Johnson JM. Diurnal variation in cutaneous vasodilator and vasoconstrictor systems during heat stress. Am J Physiol Regul Integr Comp Physiol 281: R591-R595, 2001. (Pubitemid 32756154)
2. Aoki K, Stephens DP, Zhao K, Kosiba WA, Johnson JM. Modification of cutaneous vasodilator response to heat stress by daytime exogenous melatonin administration. Am J Physiol Regul Integr Comp Physiol 291: R619-R624, 2006. (Pubitemid 44352344)
3. Bennett LA, Johnson JM, Stephens DP, Saad AR, Kellogg DL Jr. Evidence for a role for vasoactive intestinal peptide in active vasodilatation in the cutaneous vasculature of humans. J Physiol (Lond) 552: 223-232, 2003.
4. Boulant JA, Silva NL. Neuronal sensitivities in preoptic tissue slices: interactions among homeostatic systems. Brain Res Bul 20: 871-878, 1988.
5. Brengelmann GL, Savage MV. Temperature regulation in the neutral zone. Ann NY Acad Sci 813: 39-50, 1997.
6. Charkoudian N, Johnson JM. Altered reflex control of cutaneous circulation by female sex steroids is independent of prostaglandins. Am J Physiol Heart Circ Physiol 276: H1634-H1640, 1999. (Pubitemid 29246551)
7. Charkoudian N, Johnson JM. Female reproductive hormones and thermoregulatory control of skin blood flow. Exerc Sport Sci Rev 28: 108-112, 2000.
8. Charkoudian N, Johnson JM. Modification of active cutaneous vasodilation by oral contraceptive hormones. J Appl Physiol 83: 2012-2018, 1997. (Pubitemid 28006503)
9. Fortney SM, Nadel ER, Wenger CB, Bove JR. Effect of acute alterations of blood volume on circulatory performance in humans. J Appl Physiol 50: 292-298, 1981. (Pubitemid 11138208)
10. Fortney SM, Wenger CB, Bove JR, Nadel ER. Effect of hyperosmolality on control of blood flow and sweating. J Appl Physiol 57: 1688-1695, 1984. (Pubitemid 15191364)
11. Hardy JD, DuBois EF. The technic of measuring radiation and convection. J Nutr 15: 461-475, 1938.
12. Helyar R, Green H, Zappe D, Sutton J. Comparative effects of acute volume expansion and short-term training on thermal and cardiovascular responses to prolonged exercise. Can J Physiol Pharmacol 74: 1087-1094, 1996. (Pubitemid 27013999)
13. Johnson JM, Brengelmann GL, Hales JR, Vanhoutte PM, Wenger CB. Regulation of the cutaneous circulation. Fed Proc 45: 2841-2850, 1986.
14. Johnson JM, O'Leary DS, Taylor WF, Kosiba W. Effect of local warming on forearm reactive hyperaemia. Clin Physiol 6: 337-346, 1986. (Pubitemid 16005910)
15. Johnson JM, Proppe DW. Cardiovascular adjustments to heat stress. In: Handbook of Physiology: Environmental Physiology. New York, NY: Oxford Univ Press, 1996, sect. 4, vol.1, chapt. 11, p. 215-243.
16. Kellogg DL Jr, Johnson JM, Kosiba WA. Control of internal temperature threshold for active cutaneous vasodilation by dynamic exercise. J Appl Physiol 71: 2476-2482, 1991.
17. Kellogg DL Jr, Johnson JM, Kosiba WA. Selective abolition of adrenergic vasoconstrictor responses in skin by local iontophoresis of bretylium. Am J Physiol Heart Circ Physiol 257: H1599-H1606, 1989.
18. Kellogg DL Jr, Pergola PE, Piest KL, Kosiba WA, Crandall CG, Grossmann M, Johnson JM. Cutaneous active vasodilation in humans is mediated by cholinergic nerve cotransmission. Circ Res 77: 1222-1228, 1995.
19. Kellogg DL Jr, Zhao JL, Wu Y. Neuronal nitric oxide synthase control mechanisms in the cutaneous vasculature of humans in vivo. J Physiol (Lond) 586: 847-857, 2008. (Pubitemid 351194122)
20. McCord GR, Cracowski JL, Minson CT. Prostanoids contribute to cutaneous active vasodilation in humans. Am J Physiol Regul Integr Comp Physiol 291: R596-R602, 2006.
21. Mitono H, Endoh H, Okazaki K, Ichinose T, Masuki S, Takamata A, Nose H. Acute hypoosmolality attenuates the suppression of cutaneous vasodilation with increased exercise intensity. J Appl Physiol 99: 902-908, 2005. (Pubitemid 41214501)
22. Montain SJ, Coyle EF. Fluid ingestion during exercise increases skin blood flow independent of increases in blood volume. J Appl Physiol 73: 903-910, 1992.
23. Morimoto T, Itoh T. Thermoregulation and body fluid osmolality. J Basic Clin Physiol Pharmacol 9: 51-72, 1998.
24. Nadel ER, Fortney SM, Wenger CB. Effect of hydration state of circulatory and thermal regulations. J Appl Physiol 49: 715-721, 1980. (Pubitemid 10018653)
25. Nakashima T, Hori T, Kiyohara T, Shibata M. Osmosensitivity of preoptic thermosensitive neurons in hypothalamic slices in vitro. Pflugers Arch 405: 112-117, 1985. (Pubitemid 16255599)
26. Sawka MN, Montain SJ, Latzka WA. Hydration effects on thermoregulation and performance in the heat. Comp Biochem Physiol A Mol Integr Physiol 128: 679-690, 2001.
27. Shibasaki M. Nonthermoregulatory modification of sweating and skin blood flow. In: Exercise, Nutrition, and Environmental Stress, edited by Nose H, Joyner MJ, and Miki K. Traverse City, MI: Cooper Publishing Group, 2005, vol.4, p. 227-243.
28. Shibasaki M, Wilson TE, Cui J, Crandall CG. Acetylcholine released from cholinergic nerves contributes to cutaneous vasodilation during heat stress. J Appl Physiol 93: 1947-1951, 2002.
29. Silva NL, Boulant JA. Effects of osmotic pressure, glucose, and temperature on neurons in preoptic tissue slices. Am J Physiol Regul Integr Comp Physiol 247: R335-R345, 1984.
30. Takamata A, Mack GW, Gillen CM, Jozsi AC, Nadel ER. Osmoregulatory modulation of thermal sweating in humans: reflex effects of drinking. Am J Physiol Regul Integr Comp Physiol 268: R414-R422, 1995.
31. Takamata A, Morimoto T, Nose H. Interrelationship between osmoregulation and thermoregulation in a hot environment and during exercise. In: Exercise, Nutrition, and Environmental Stress, edited by Nose H, Gisolfi CV, and Imaizumi K. Traverse City, MI: Cooper, 2001, vol.1, p. 179-219.
32. Takamata A, Nagashima K, Nose H, Morimoto T. Osmoregulatory inhibition of thermally induced cutaneous vasodilation in passively heated humans. Am J Physiol Regul Integr Comp Physiol 273: R197-R204, 1997. (Pubitemid 127751403)
33. Takamata A, Nagashima K, Nose H, Morimoto T. Role of plasma osmolality in the delayed onset of thermal cutaneous vasodilation during exercise in humans. Am J Physiol Regul Integr Comp Physiol 275: R286-R290, 1998. (Pubitemid 28376319)
34. Takamata A, Yoshida T, Nishida N, Morimoto T. Relationship of osmotic inhibition in thermoregulatory responses and sweat sodium concentration in humans. Am J Physiol Regul Integr Comp Physiol 280: R623-R629, 2001. (Pubitemid 32494064)
35. Takeno Y, Kamijo Y, Nose H. Thermoregulatory and aerobic changes after endurance training in a hypobaric hypoxic and warm environment. J Appl Physiol 91: 1520-1528, 2001. (Pubitemid 32900342)
36. Taylor WF, Johnson JM, O'Leary D, Park MK. Effect of high local temperature on reflex cutaneous vasodilation. J Appl Physiol 57: 191-196, 1984. (Pubitemid 14098698)
37. Wong BJ, Minson CT. Neurokinin-1 receptor desensitization attenuates cutaneous active vasodilatation in humans. J Physiol (Lond) 577: 1043-1051, 2006.
38. Wong BJ, Wilkins BW, Minson CT. H1 but not H2 histamine receptor activation contributes to the rise in skin blood flow during whole body heating in humans. J Physiol (Lond) 560: 941-948, 2004.