Proneurotrophin-3 is a neuronal apoptotic ligand: Evidence for retrograde-directed cell killing

Journal of Neuroscience

Volumn 29, Issue 47, 2009, Pages 14790-14802

  Yano, Hiroko ^a,d   Torkin, Risa ^b,c,e   Martin, Laura Andrés ^b   Chao, Moses V ^a   Teng, Kenneth K ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e ACORDA THERAPEUTICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; LIGAND; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR P75; PRONEUROTROPHIN 3; PROTEIN ANTIBODY; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; SORTILIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL KILLING; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INNERVATION; MEMBRANE DEPOLARIZATION; NERVE CELL; NERVE CELL NECROSIS; NERVE FIBER; NERVOUS SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL NERVE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SYMPATHETIC NERVE CELL; WESTERN BLOTTING;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; AXONAL TRANSPORT; CELL LINE; CELLS, CULTURED; GANGLIA, SYMPATHETIC; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIGANDS; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; NERVE DEGENERATION; NERVE GROWTH FACTOR; NERVOUS SYSTEM; NEURONS; NEUROTROPHIN 3; PC12 CELLS; RATS; RECEPTORS, NERVE GROWTH FACTOR;

EID: 72449207064     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2059-09.2009     Document Type: Article

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