Antiangiogenesis therapy might have the unintended effect of promoting tumor metastasis by increasing an alternative circulatory system

Medical Hypotheses

Volumn 74, Issue 2, 2010, Pages 360-361

  Qu, Bo ^a   Guo, Long ^a   Ma, Jinlu ^a   Lv, Yi ^a  

^a First Affiliated Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOSTATIN; ENDOSTATIN;

ANTIANGIOGENIC THERAPY; ARTICLE; CANCER THERAPY; CARDIOVASCULAR SYSTEM; CELL PROLIFERATION; DISEASE ASSOCIATION; DISEASE COURSE; ENDOTHELIUM CELL; GENE EXPRESSION; GENETIC ASSOCIATION; HUMAN; HYPOTHESIS; HYPOXIA; METASTASIS; MULTIPLE CANCER; ONCOLOGICAL PARAMETERS; PRIORITY JOURNAL; PROGNOSIS; TUMOR CELL; TUMOR GROWTH; TUMOR VASCULARIZATION; VASCULOGENIC MIMICRY;

ANGIOGENESIS INHIBITORS; HUMANS; MICROCIRCULATION; MODELS, BIOLOGICAL; NEOPLASM METASTASIS; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; NEOVASCULARIZATION, PATHOLOGIC;

EID: 72449192192     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.08.020     Document Type: Article

References (17)

1. Carmeliet P., and Jain R.K. Angiogenesis in cancer and other diseases. Nature 407 6801 (2000) 249-257
2. Jain R.K. Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy. Science 307 5706 (2005) 58-62
3. Hillen F., and Griffioen A.W. Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev (2007)
4. Maniotis A.J., Folberg R., Hess A., et al. Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry. Am J Pathol 155 3 (1999) 739-752
5. Folberg R., and Maniotis A.J. Vasculogenic mimicry. APMIS 112 7-8 (2004) 508-525
6. Frenkel S., Barzel I., Levy J., et al. Demonstrating circulation in vasculogenic mimicry patterns of uveal melanoma by confocal indocyanine green angiography. Eye (2007)
7. Lin A.Y., Ai Z., Lee S.C., et al. Comparing vasculogenic mimicry with endothelial cell-lined vessels: techniques for 3D reconstruction and quantitative analysis of tissue components from archival paraffin blocks. Appl Immunohistochem Mol Morphol 15 1 (2007) 113-119
8. Chen X., Ai Z., Rasmussen M., et al. Three-dimensional reconstruction of extravascular matrix patterns and blood vessels in human uveal melanoma tissue: techniques and preliminary findings. Invest Ophthalmol Vis Sci 44 7 (2003) 2834-2840
9. Guzman G., Cotler S.J., Lin A.Y., Maniotis A.J., and Folberg R. A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma. Arch Pathol Lab Med 131 12 (2007) 1776-1781
10. Zhao H., and Gu X.M. Study on vasculogenic mimicry in malignant esophageal stromal tumors. World J Gastroenterol 14 15 (2008) 2430-2433
11. Sun B., Zhang S., Zhang D., et al. Vasculogenic mimicry is associated with high tumor grade, invasion and metastasis, and short survival in patients with hepatocellular carcinoma. Oncol Rep 16 4 (2006) 693-698
12. Fan Y.Z., Sun W., Zhang W.Z., and Ge C.Y. Vasculogenic mimicry in human primary gallbladder carcinoma and clinical significance thereof. Zhonghua Yi Xue Za Zhi 87 3 (2007) 145-149
13. der Schaft D.W.v., Seftor R.E., Seftor E.A., et al. Effects of angiogenesis inhibitors on vascular network formation by human endothelial and melanoma cells. J Natl Cancer Inst 96 19 (2004) 1473-1477
14. Rybak S.M., Sanovich E., Hollingshead M.G., et al. "Vasocrine" formation of tumor cell-lined vascular spaces: implications for rational design of antiangiogenic therapies. Cancer Res 63 11 (2003) 2812-2819
15. der Schaft D.W.J.v., Hillen F., Pauwels P., et al. Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer Res 65 24 (2005) 11520-11528
16. Robertson G.P. Mig-7 linked to vasculogenic mimicry. Am J Pathol 170 5 (2007) 1454-1456
17. Petty A.P., Garman K.L., Winn V.D., Spidel C.M., and Lindsey J.S. Overexpression of carcinoma and embryonic cytotrophoblast cell-specific Mig-7 induces invasion and vessel-like structure formation. Am J Pathol 170 5 (2007) 1763-1780