Hydrophobic solvent induced phase transition extraction to extract drugs from plasma for high performance liquid chromatography-mass spectrometric analysis

Journal of Chromatography A

Volumn 1217, Issue 3, 2010, Pages 243-249

  Liu, Guozhu ^a   Zhou, Naiyuan ^a,b   Zhang, Mingshan ^a   Li, Shengjun ^a   Tian, Qingqing ^a   Chen, Jitao ^a   Chen, Bo ^a   Wu, Yongning ^c   Yao, Shouzhuo ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

^b China National Center for Biotechnology Development   (China)

^c CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

Acetonitrile; HPLC MS; Plasma; Solvent induced phase transition extraction

Indexed keywords

ALTERNATIVE APPROACH; ANALYTES; AQUEOUS MIXTURES; BIOANALYSIS; HPLC-MS; HPLC-MS ANALYSIS; HYDROPHOBIC SOLVENT; LIQUID-LIQUID EXTRACTION; MASS SPECTROMETRIC ANALYSIS; MOLECULAR INTERFERENCE; PLASMA SAMPLES; POTENTIAL PROBLEMS; PRE-CONCENTRATION; SALTING-OUT; SAMPLE PREPARATION; SAMPLE SOLVENT; SOLVENT INDUCED; SOLVENT INDUCED PHASE TRANSITION EXTRACTION; SUB-ZERO TEMPERATURES;

ACETONITRILE; CHROMATOGRAPHIC ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROPHOBIC CHROMATOGRAPHY; HYDROPHOBICITY; LIQUIDS; ORGANIC SOLVENTS; PHASE SEPARATION; PHASE TRANSITIONS; PLASMAS; SOLVENTS;

SOLVENT EXTRACTION;

ACETONITRILE; ANDROGRAPHOLIDE; FINASTERIDE; SILDENAFIL;

ANALYTIC METHOD; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; EXPERIMENTAL DESIGN; EXPERIMENTAL TEST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROPHOBICITY; INTERMETHOD COMPARISON; MASS SPECTROMETRY; PHASE SEPARATION; PLASMA; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SOLVENT INDUCED PHASE TRANSITION EXTRACTION; VALIDATION PROCESS;

ACETONITRILES; CHEMICAL FRACTIONATION; CHLOROFORM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES; FINASTERIDE; HUMANS; HYDROPHOBICITY; MASS SPECTROMETRY; MODELS, MOLECULAR; PHARMACEUTICAL PREPARATIONS; PIPERAZINES; PURINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFONES;

EID: 72449188292     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2009.11.037     Document Type: Article

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