Complete remission of nephrotic syndrome and improvement of renal function in a patient with light chain deposition disease following high dose chemotherapy with transplantation of autologous haematopoietic stem cells. A case study and review of literature;Vymizení nefrotického syndromu a zlepšení funkce ledvin u nemocné s light chain deposition disease po vysokodávkované chemoterapii s autologní transplantací kmenových krvetvorných buněk. Popis případu a přehled literatury

Vnitrni Lekarstvi

Volumn 55, Issue 11, 2009, Pages 1089-1096

  Adam, Zdeněk ^a   Krejci M ^a   Pour, L ^a   Stepankova S ^b   Cermakova Z ^c   Voska, L ^d   Teplan, V ^d   Krivanova A ^a   Hajek R ^a   Mayer, J ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL BRNO   (Czech Republic)

^c Oddeleni Klinicke Biochemie   (Czech Republic)

^d INSTITUTE FOR CLINICAL AND EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

High dose chemotherapy with autologous peripheral stem cell transplantation; Light chain deposition disease; Monoclonal gammapathy; Multiple myeloma; Nephrotic syndrome; Renal insuficiency

Indexed keywords

CREATININE; DEXAMETHASONE; DOXORUBICIN; MELPHALAN; PARAPROTEIN; VINCRISTINE;

ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; BONE MARROW BIOPSY; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CANCER STAGING; CASE REPORT; CREATININE BLOOD LEVEL; FEMALE; GLOMERULUS FILTRATION; HEALTH SURVEY; HUMAN; HYPOALBUMINEMIA; HYPONATREMIA; KIDNEY AMYLOIDOSIS; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY INJURY; LIGHT CHAIN DEPOSITION DISEASE; MULTIPLE CYCLE TREATMENT; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; NEPHROTOXICITY;

ADULT; ANTINEOPLASTIC AGENTS, ALKYLATING; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COMBINED MODALITY THERAPY; DRUG RESISTANCE, NEOPLASM; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; KIDNEY; MELPHALAN; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; REMISSION INDUCTION; TRANSPLANTATION, AUTOLOGOUS;

EID: 72449178345     PISSN: 0042773X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Randall RE, Williamson WC jr, Mulinax F et al. Manifestation of systemic light chain deposition. Am J Med 1976; 60: 293-299.
2. Heilman RL, Velosa JA, Holley KE et al. Long term follow up and response to chemotherapy in patients with light chain deposition disease. Am J Kidney Dis 1992; 20: 34-41.
3. Pozzi C, Fogazzi GB, Banfi G et al. Renal disease and patient survival in light chain deposition disease. Clin Nephrol 1995; 43: 281-287.
4. Cogné M, Preud'homme JL, Bauwens M. Structure of monoclonal kappa chain of the V kappa IV subgroup in the kidney and plasma cells in light chain deposition disease. J Clin Invest 1991; 87: 2186-2190.
5. Wahner-Roedler DL, Kyle RA. Heavy chain diseases. Best Pract Res Clin Hematol 2005; 18: 729-746.
6. van Ingen G, van Bronswijk H, Meijer CJ et al. Light chain deposition disease without detectable light chains in serum or urine. Report of a case and review of the literature. Neth J Med 1991; 39: 142-147.
7. Sakakima M, Fujigaki Y, Tsuji T et al. High dose chemotherapy and stem cell support in a patient of light- and heavy-chain deposition disease with abnormal marrow cell surface antigens and no monoclonal protein. Intern Med 2005; 44: 970-974. (Pubitemid 41644098)
8. Steuhl KP, Knorr C, Rohrbach JM et al. Paraproteinemic corneal deposits in plasma cell myeloma. Am J Ophthalmol 1991; 111: 312-318.
9. Pelletier G, Fabre M, Attali P et al. Light chain deposition disease presenting with hepatomegaly: an association with amyloid-like fibrils. Postgrad Med J 1988; 64: 804-808. (Pubitemid 18260280)
10. Kijner CH, Yousem SA. Systemic light chain deposition disease presenting as multiple pulmonary nodules. A case report and review of the literature. Am J Surg Pathol 1988; 12: 405-413.
11. Girelli CM, Lodi G, Rocca F. Kappa light chain deposition of the liver. Eur J Gastroenterol Hepatol 1998; 10: 429-430. (Pubitemid 28241431)
12. Wohl P, Chadimová M, Englis M et al. Light chain deposition disease as a cause of renal failure. Čas Lék Česk 1998; 137: 721-724.
13. Merta M, Rysavá R, Zabka J et al. Kidney involvement in light-chain deposition disease. Sb Lek 2002; 103: 397-403.
14. Zhu L, Herrera GA, Murphy-Ullrich JE et al. Pathogenesis of glomerulosclerosis in light chain deposition disease. Role for transforming growth factor-beta. Am J Pathol 1995; 147: 375-385.
15. Preud'homme JL, Aucouturier P, Touchard G et al. Monoclonal immunoglobulin deposition disease (Randall type). Relationship with structural abnormalities of immunoglobulin chains. Kidney Int 1994; 46: 965-972.
16. Venkataseshan VS, Faraggiana T, Hughson MD et al. Morphologic variants of light-chain deposition disease in the kidney. Am J Nephrol 1988; 8: 272-279.
17. Salant DJ, Sanchorawala V, D'Agati VD. A case of atypical light chain deposition disease - diagnosis and treatment. Clin J Am Soc Nephrol 2007; 2: 858-867.
18. Baur A, Stäbler A, Lamerz R et al. Light chain deposition disease in multiple myeloma: MR imaging features correlated with histopathological findings. Skeletal Radiol 1998; 27: 173-176. (Pubitemid 28181765)
19. Ferrario F, Rastaldi MP. Histopathological atlas of renal diseases: light chain deposition disease. J Nephrol 2005; 18: 499-502. (Pubitemid 41824468)
20. Gokden N, Barlogie B, Liapis H. Morphologic heterogeneity of renal light-chain deposition disease. Ultrastruct Pathol 2008; 32: 17-24. (Pubitemid 351323398)
21. Joh K. Pathology of glomerular deposition diseases. Pathol Int 2007; 57: 551-565.
22. Gu X, Herrera AG. Light chain mediated acute tubular interstitial nephritis: a poorly recognized pattern of renal disease in patients with plasma cell dyscrasia. Arch Pathol Lab Med 2006; 130: 165-169. (Pubitemid 43237983)
23. Ganeval D, Noël LH, Preud'homme JL et al. Light chain deposition disease: Its relation with AL type amyloidosis. Kidney Int 1984; 26: 1-9.
24. Hofmann-Guilaine C, Nochy D, Jacquot C et al. Association light chain deposition disease (LCDD) and amyloidosis. One case. Pathol Res Pract 1985; 180: 214-219.
25. Jacquot C, Saint-Andre JP, Touchard G et al. Association of systemic light-chain deposition disease and amyloidosis: a report of three patients with renal involvement. Clin Nephrol 1985; 24: 93-98. (Pubitemid 15023014)
26. Lin J, Markowitz GS, Valeri AM et al. Renal monoclonal immunoglobulin deposition disease. The disease spectrum. J Am Soc Nephrol 2001; 12: 1482-1492. (Pubitemid 32666331)
27. Pozzi C, D'Amico M, Fogazzi GB et al. Light chain deposition disease with renal involvement: clinical characteristics and prognostic factor. Am J Kidney Dis 2003; 42: 1154-1163. (Pubitemid 37486758)
28. Leung N, Lager DJ, Gertz MA et al. Long-term outcome of renal transplantation in light-chain deposition disease. Am J Kidney Dis 2004; 43: 147-153. (Pubitemid 38049446)
29. Royer B, Arnulf B, Martinez F et al. High dose chemotherapy in light chain or light and heavy chain deposition disease. Kidney Int 2004; 65: 642-648. (Pubitemid 38130660)
30. Barraclough KA, Dowling JP, Schwarer AP et al. Sequential autologous peripheral blood stem cell transplantation and kidney transplantation of light chain deposition disease. Nephrol Dial Transplant 2007; 22: 1268-1269.
31. Brockhurst I, Harris KP, Chapman CS. Diagnosis and monitoring a case of light-chain deposition disease in the kidney using a new, sensitive immunoassay. Nephrol Dial Transplant 2005; 20: 1251-1253. (Pubitemid 40862121)
32. Firkin F, Hill PA, Dwyer K et al. Reversal of dialysis dependent renal failure in light chain deposition disease by autologous peripheral blood stem cell transplantation. Am J Kidney Dis 2004; 44: 551-555. (Pubitemid 39164631)
33. Gertz MA, Lacy MQ, Lust JA et al. Phase II trial of high-dose dexamethasone for untreated patients with primary systemic amyloidosis. Med Oncol 1999; 16: 104-109.
34. Hassoun H, Flombaum C, D'Agati VD et al. High-dose melphalan and auto-SCT in patients with monoclonal Ig deposition disease. Bone Marrow Transplant 2008; 42: 405-412.
35. Kastritis E, Migkou M, Gavriatopoulou M et al. Treatment of light chain deposition disease with bortezomib and dexamethasone. Haematologica 2009; 94: 300-302.
36. Kirkpatrick CJ, Curry A, Galle J et al. Systemic kappa light chain deposition and amyloidosis in multiple myeloma: novel morphological observations. Histopathology 1986; 10: 1065-1076. (Pubitemid 16008604)
37. Lambotte O, Dürrbach A, Ammor M et al. Association of a POEMS syndrome and light chain deposit disease: first case report. Clin Nephrol 2001; 55: 482-486. (Pubitemid 32499504)
38. Lorenz EC, Gertz MA, Fervenza FC et al. Long-term outcome of autologous stem cell transplantation in light chain deposition disease. Nephrol Dial Transplant 2008; 23: 2052-2057.
39. Pineda-Roman M, Tricot G. High-dose therapy in patients with plasma cell dyscrasias and renal dysfunction. Contrib Nephrol 2007; 153: 182-194. (Pubitemid 44836021)
40. Samanez C, Domingo A, Cibeira MT. Development of rapidly progressive liver light chain deposition under VAD chemotherapy in multiple myeloma. Eur J Haematol 2006; 76: 83-85.
41. Sanchorawala V, Wright DG, Seldin DC et al. An overview of the use of high-dose melphalan with autologous stem cell transplantation for the treatment of AL amyloidosis. Bone Marrow Transplant 2001; 28: 637-642.
42. Weichman K, Dember LM, Prokaeva T et al. Clinical and molecular characteristics of patients with non-amyloid light chain deposition disorders, and outcome following treatment with high dose melphalan and autologous stem cell transplantation. Bone Marrow Transplantatin 2006; 38: 339-343. (Pubitemid 44241542)
43. Leung N, Slezak JM, Bertstralh EJ. Acute renal insufficiency after high dose melphalan in patients with primary systemic amyloidosis during stem cell transplantation. Am J Kidney Dis 2005; 45: 102-111. (Pubitemid 40038050)
44. Comezo RL. Managing systemic light chain amyloidosis. J Natl Compr Canc Netw 2007; 5: 179-187.
45. Bedossa P, Fabre M, Paraf F et al. Light chain deposition disease with liver dysfunction. Hum Pathol 1988; 19: 1008-1014. (Pubitemid 18239497)
46. Bhargava P, Rushin JM, Rusnock EJ et al. Pulmonary light chain deposition disease. Report of five cases and review of literature. Am J Surg Pathol 2007; 31: 267-276. (Pubitemid 46175028)
47. Popovic M, Tavcar R, Glavac D et al. Light chain deposition disease restricted to the brain: the first case report. Hum Pathol 2007; 38: 179-184. (Pubitemid 44880214)
48. Doubek M, Brychtova Y, Tomiska M et al. Idiopathic systemic capillary leak syndrome misdiagnosed and treated as polycythemia vera. Acta Haematol 2005; 113: 150-151. (Pubitemid 40522821)