Bacterial growth rate and host factors as determinants of intracellular bacterial distributions in systemic Salmonella enterica infections

Infection and Immunity

Volumn 77, Issue 12, 2009, Pages 5608-5611

  Grant, Andrew J ^a   Foster, Gemma L ^a   McKinley, Trevelyan J ^a   Brown, Sam P ^b   Clare, Simon ^c   Maskell, Duncan J ^a   Mastroeni, Pietro ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; BACTERIAL STRAIN; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DYNAMICS; GROWTH RATE; IN VIVO STUDY; INTRACELLULAR BACTERIUM; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; TYPHOID FEVER;

ANIMALS; COLONY COUNT, MICROBIAL; CYTOPLASM; FEMALE; HOST-PATHOGEN INTERACTIONS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MODELS, THEORETICAL; PHAGOCYTES; SALMONELLA ENTERICA; SALMONELLA INFECTIONS, ANIMAL;

EID: 72449174257     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00827-09     Document Type: Article

References (18)

1. Brown, S. P., S. J. Cornell, M. Sheppard, A. J. Grant, D. J. Maskell, B. T. Grenfell, and P. Mastroeni. 2006. Intracellular demography and the dynamics of Salmonella enterica infections. PLoS Biol. 4:2091-2098.
2. Foster, G. L., T. A. Barr, A. J. Grant, T. J. McKinley, C. E. Bryant, A. MacDonald, D. Gray, M. Yamamoto, S. Akira, D. J. Maskell, and P. Mastroeni. 2008. Virulent Salmonella enterica infections can be exacerbated by concomitant infection of the host with a live attenuated Salmonella enterica vaccine via TLR4-dependent IL-10 production with the involvement of both TRIF and MyD88. Immunology 124:469-479.
3. Grant, A. J., O. Restif, T. J. McKinley, M. Sheppard, D. J. Maskell, and P. Mastroeni. 2008. Modelling within-host spatiotemporal dynamics of invasive bacterial disease. PLoS Biol. 6:e74.
4. - Salmonella typhimurium is enhanced by neutralization of gamma interferon and tumor necrosis factor alpha. Infect. Immun. 65:5191-5197.
5. Hess, J., C. Ladel, D. Miko, and S. H. Kaufmann. 1996. Salmonella typhimurium aroA- infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location. J. Immunol. 156:3321-3326.
6. Hormaeche, C. E. 1979. Natural resistance to Salmonella typhimurium in different inbred mouse strains. Immunology 37:311-318.
7. Mastroeni, P., J. N. Skepper, and C. E. Hormaeche. 1995. Effect of antitumor necrosis factor alpha antibodies on histopathology of primary Salmonella infections. Infect. Immun. 63:3674-3682.
8. Mastroeni, P., J. A. Harrison, J. H. Robinson, S. Clare, S. Khan, D. J. Maskell, G. Dougan, and C. E. Hormaeche. 1998. Interleukin-12 is required for control of the growth of attenuated aromatic-compound-dependent salmonellae in BALB/c mice: role of gamma interferon and macrophage activation. Infect. Immun. 66:4767-4776.
9. Mastroeni, P., S. Clare, S. Khan, J. A. Harrison, C. E. Hormaeche, H. Okamura, M. Kurimoto, and G. Dougan. 1999. Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect. Immun. 67:478-483.
10. Mastroeni, P., A. Vazquez-Torres, F. C. Fang, Y. Xu, S. Khan, C. E. Hormaeche, and G. Dougan. 2000. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo. J. Exp. Med. 192:237-248.
11. Mastroeni, P., and M. Sheppard. 2004. Salmonella infections in the mouse model: host resistance factors and in vivo dynamics of bacterial spread and distribution in the tissues. Microbes Infect. 6:398-405.
12. Muotiala, A., and P. H. Makela. 1990. The role of IFN-gamma in murine Salmonella typhimurium infection. Microb. Pathog. 8:135-141.
13. Muotiala, A., and P. H. Mäkelä. 1993. Role of gamma interferon in late stages of murine salmonellosis. Infect. Immun. 61:4248-4253.
14. R Development Core Team. 2008. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. http://www.R-project.org.
15. Richter-Dahlfors, A., A. M. J. Buchan, and B. B. Finlay. 1997. Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo. J. Exp. Med. 186:569-580.
16. Sheppard, M., C. Webb, F. Heath, V. Mallows, R. Emilianus, D. Maskell, and P. Mastroeni. 2003. Dynamics of bacterial growth and distribution within the liver during Salmonella infection. Cell. Microbiol. 5:593-600.
17. Vazquez-Torres, A., J. Jones-Carson, P. Mastroeni, H. Ischiropoulos, and F. C. Fang. 2000. Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. I. Effects on microbial killing by activated peritoneal macrophages in vitro. J. Exp. Med. 192:227-236.
18. White, J. A., P. Mastroeni, J.-F. Popoff, C. A. Evans, and J. M. Blackwell. 2004. Slc11a1-mediated resistance to Salmonella enterica serovar Typhimurium and Leishmania donovani does not require functional inducible nitric oxide synthase or phagocyte oxidase activity. J. Leukoc. Biol. 77:311-320.